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The map label for this gene is rpl18p [H]

Identifier: 227827710

GI number: 227827710

Start: 1349344

End: 1349934

Strand: Direct

Name: rpl18p [H]

Synonym: M1425_1439

Alternate gene names: 227827710

Gene position: 1349344-1349934 (Clockwise)

Preceding gene: 227827709

Following gene: 227827711

Centisome position: 51.72

GC content: 34.52

Gene sequence:

>591_bases
TTGGCCAATGGTCCTAATTATAAGATAAAACCTAGGAGAAGAAGAGAAGGAAAAACTAACTACTATAAGAGATATGTTTA
TGTCATAAGTAAACAAATAAGGTTTATTGTAAGAATAACGAACAAATACGTTATAGTTCAAATTGCAAAAATCGATCCTA
AGGGCGATATCATGGTTGCTAGTGCTCATTCTTCAGAACTTACTAAAAAGTTTGAATGGAAGGGAGATGAAAATAATACT
CCCTCCGCATACCTTACTGGATATTTAGCAGCTTTAAGAGCTGTGAAGAAAGGCGTAACAGAGTGTGTTGCAGATATAGG
ACTTCATGTACCGTCCAAGGGTAATAAGGTGTTCTATGCAATAAAAGGTGCAATAGATGCTGGGTTGAAAATTCCGATAG
GTGATATAAGTATAGAAAACGATAGAATAAAGGGAGAGCATATAGCCAAGTATGCTGAAAAGTTGAAATCTGAGAATTTA
GATTTATATAATAAACTATTTTCAAGGTATTTGGGAAGGGGACTAAATCCTGAGAACTTACCCTCTCATTTTGAGGAGAT
ATTAAACAAGATTAAATCTTCTGGTGGTTGA

Upstream 100 bases:

>100_bases
ATAGGGAATTATACTTAAAAGCCAAGGGTGGCAACTATAAGGGAGTTTCAGATGTTAGGAACGTCTTAATACAGATGGGG
AAATTAAGAGGTGAGTAAAT

Downstream 100 bases:

>100_bases
AATGGCAGAGGAAGTACCAAGTATAAATATAGAAGAATGGAAGCCACGAACCTCCATAGGTAATCTCGTAAAGAATGGAA
AGATATCATCTATAAAGGAA

Product: 50S ribosomal protein L18P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MANGPNYKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKIDPKGDIMVASAHSSELTKKFEWKGDENNT
PSAYLTGYLAALRAVKKGVTECVADIGLHVPSKGNKVFYAIKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENL
DLYNKLFSRYLGRGLNPENLPSHFEEILNKIKSSGG

Sequences:

>Translated_196_residues
MANGPNYKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKIDPKGDIMVASAHSSELTKKFEWKGDENNT
PSAYLTGYLAALRAVKKGVTECVADIGLHVPSKGNKVFYAIKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENL
DLYNKLFSRYLGRGLNPENLPSHFEEILNKIKSSGG
>Mature_195_residues
ANGPNYKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKIDPKGDIMVASAHSSELTKKFEWKGDENNTP
SAYLTGYLAALRAVKKGVTECVADIGLHVPSKGNKVFYAIKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENLD
LYNKLFSRYLGRGLNPENLPSHFEEILNKIKSSGG

Specific function: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [H]

COG id: COG0256

COG function: function code J; Ribosomal protein L18

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L18P family [H]

Homologues:

Organism=Homo sapiens, GI14591909, Length=236, Percent_Identity=30.5084745762712, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17534333, Length=235, Percent_Identity=34.0425531914894, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6325126, Length=227, Percent_Identity=30.3964757709251, Blast_Score=89, Evalue=4e-19,
Organism=Drosophila melanogaster, GI116007384, Length=235, Percent_Identity=31.063829787234, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI116007382, Length=235, Percent_Identity=31.063829787234, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005484
- InterPro:   IPR005485 [H]

Pfam domain/function: PF00861 Ribosomal_L18p [H]

EC number: NA

Molecular weight: Translated: 22091; Mature: 21960

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANGPNYKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKIDPKGDIMVA
CCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHEEEEEECCEEEEEEEEECCCCCEEEE
SAHSSELTKKFEWKGDENNTPSAYLTGYLAALRAVKKGVTECVADIGLHVPSKGNKVFYA
ECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENLDLYNKLFSRYLGRGLNPENL
EECCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PSHFEEILNKIKSSGG
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANGPNYKIKPRRRREGKTNYYKRYVYVISKQIRFIVRITNKYVIVQIAKIDPKGDIMVA
CCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHEEEEEECCEEEEEEEEECCCCCEEEE
SAHSSELTKKFEWKGDENNTPSAYLTGYLAALRAVKKGVTECVADIGLHVPSKGNKVFYA
ECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IKGAIDAGLKIPIGDISIENDRIKGEHIAKYAEKLKSENLDLYNKLFSRYLGRGLNPENL
EECCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PSHFEEILNKIKSSGG
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726 [H]