Click here to switch to the map view.

The map label for this gene is ileS

Identifier: 227827689

GI number: 227827689

Start: 1336041

End: 1339190

Strand: Direct

Name: ileS

Synonym: M1425_1418

Alternate gene names: 227827689

Gene position: 1336041-1339190 (Clockwise)

Preceding gene: 227827688

Following gene: 227827690

Centisome position: 51.21

GC content: 34.51

Gene sequence:

>3150_bases
ATTAAGCCTCTTACTGGTAATTATGATCCTAAGAAGATCGAAGACGAAATAATTTCATTTTGGGAAGAGAATAAAATTTA
CAATAAATTAAGAGATATTGTAAGTAAAAGAAGGGAAAAGTTTCTGTTTATAGATGGCCCTCCATATCCTTCAAGCCCTA
CTCCTCATATAGGGACTATTTGGAATAAGGTAATAAAGGACTGTATATTGCGCTATGAAAGATTACTAGGTAAAAAAGTT
CATGACCAACCAGGATATGATACACATGGATTACCTATAGAAGTTGCAACTGAAAGGCTACTTGGAATATTAAATAAGCA
AGAGATTATAGATAAAATTGGAGTAGAGAATTTCATTAATAAATGCAAAGAGTTTGCGTTATCCAATGCGACTAAAATGA
CACAAAACTTTAAGGACGTTGGAGTCTTTATGGATTGGGAAAGGCCTTACTATACATTAGACCCTTCTTATATAAGCTCT
TCATGGAGCGTAATTAAGAAAGCTTATGAAAAAGGGATGTTAGATAAGGGTACCGCAGTATTACATTGGTGTCCTAGATG
TGAAACAACTCTATCAGATTATGAAGTGTCGGAGTATAGGGATTTAGAGGATCCTTCGATCTATGTTAAGTTTAAGATTA
AAGGAGAGGAAAATAGATACCTATTAATATGGACTACTACACCATGGACTATACCATCTAATGTTTTTGTAATGGTAAAT
AAAGACTATGATTATGCTGATGTAGAGGTTAATGGTGAGGTACTAGTACTTGCAAAAGATCGTATAGAGGCTGTTATGAA
AGAGGCAAGTATAACTAATTATAAGGTACTCAGAACCTACAAAGGCAGTGAGTTAATAGGAGTAAAATACAAGCATCCCC
TAAGAGATTTTGTTAGCGCACAAACTAAATTAGATGATTTTCATCAAGTTGTAGATGCTGGTAATGTAGTTACATTAACC
GATGGTACCGGTCTTGTACATGCTGCCACTGGACATGGTGAAGAAGACTTCTTGATAGGTCAAAAATATGGCTTTCCAGT
AGTAATGTTCGTTAATGATAGGGGAGAATTTACTGAAGAAGGTGGGAAATATAAAGGATTGAAAGTTAGAGACGCATCTA
AGGTGATAATTAACGATCTGAAGTCGAAAAACGCTTTATTCTTCGAAGGGAAAATAGTTCACCGTTATCCAGTATGTTGG
AGATGTAAGACTCCATTAGTACTTAGGGCTATTGATCAGTGGTTCATAAGAGTCACGAAAATAAAAGATGAAATGCTTAA
GGAGATAGAGAATGTAAACTGGATTCCGGATTGGGGTAAATCCAGAATATCTAACATGGTTAAGGAGCTTAGAGATTGGG
TTATAAGTAGGCAAAGGTTCTGGGGAACTCCTCTTCCTATATGGATTTGTGAAAAGTGCAATAATGTGATAGTAGTTGGA
AGTAGAGAAGACTTAGAGAGTATAGCAATAGATTCAGTTCCTAACGATTTACATAGACCGTGGATAGATAATGTAAGGGT
AAAATGTAATAAGTGCGGTGGAGTTGCTAAGAGAATTGCTGATGTGGCAGACGTTTGGTTCGATAGTGGTGTGGCTTTCT
TTGCTAGTTTAGGTAAAGATTGGCAAGAGAAGTGGAAGGAGTTAGGTCCAGTAGATCTAGTTCTAGAAGGTCATGATCAG
TTAAGGGGTTGGTTCTTTAGTTTGCTTAGATCTGGGTTAATATTGCTAGATAAAGCCCCCTATGTTTCTGTATTAGTTCA
TGGATTTATGCTAGACGAACAAGGTAGAGAAATGCATAAGAGTCTAGGCAATTATGTCGAACCTTCTGTAGTAATTCAAA
GGTATGGAAGGGATATATTACGTTTATGGCTTCTCAGAAACACTACATGGGAGGATGCAAGATTTTCATGGAGAGCGTTA
GAGCTAACTAAAAGGGATTTGCAAATAATTTGGAACACGTACGTCTTTGCATCAATGTATATGAATTTGGATAACTTTGA
ACCCGTTAAGTATACTCTTGACGATGTTATAAAATATGCTAAGATAGAAGATTTATGGATACTATCGAGATTTAACTCAA
TGTTAAAGAAGGTAAATGAGTCAATGAAGAATTATAAGGTTCATGAAATGGCTAATTACTTGATAAACTTTCTAGTTGAA
GATGTAAGCAGGTTTTACATAAGGTTAATAAGAAAAAGAGCGTGGATTGAAGCTAACACTCAGGATAAGATAGCAATGTA
TTATATTCTCTATTTCATATTAAAACAATGGATTATATTAGCATCTACTATAATTCCGTTTATTTCAGAGAAAATTTATA
AATCCTTTGTAGTTAATCCTAAGGAATCAGTATCAATGGAGTCTAGTATTAATTACGATGAGAGATTTATCGATAATGAA
TTAGAAAGAGCTTTTGAAGTTGCCAGGGAAATAAACGAGGCGTCGTTAAACGCTAGAGCTAAGGCTGGAATAAAATTAAG
ATGGCCATTGGCTAAGGTTTATATTTTCGTAGAAGATGAGGATACGTTGGCTAAGGTTAATAGAATAAAAGATGTCTTGT
TATCTCTGCTAAACGCTAAAGATATAGAAATAAGTAAAATAGAAGGATTCAAAAGTTTCAGTAAATATAAGGTCGAGCCT
AATAGGTCGATCATAGGTAAAGAGTATAAGAGTATGTCTCCTAAAATATTGGATTATATTAGAAATAATAGCGATATAAT
AGCTATAGACATACTTAATAAAAAACAGCACGTTGCTAGAATAGATAATGTTGATGTAATACTTAATACTTCGCACGTGA
TTATCTCAGAAGAGACTATTGAAGGTTATGTTTCATCTAAATTTGCTCAAGGTATAGTGGTCATAAGTAAGGAAATTTCC
GAGAGTGAAGAGGAAGAGGGATTAGTTAGGGACATCATAAGGAGGATACAATTCATGAGAAAACAACTAAAACTGAATGT
TGTAGATTATATTGAGATTAGTATAAAGGCGCCAGAAGAAAGAGTAAAAACGATACAAAAATGGGAGGAATTTATTAAGA
GTGAGACTAGGGGGAATAAGGTAATTTTAGGTGATCCTAAAGGGGATATCGTAATGGATTGGGATATAGAAGGAGAATCT
TATATAATAGGGATAAAGAAGTCTACATGA

Upstream 100 bases:

>100_bases
ATATGATATATGTGTGATGTAAGGTTGATTGGGTACGAAGTTTAATTTTTATAAACTTGTCAAGTTTAATAGGGTATGGT
GAGTTGAATTATCCACCGTT

Downstream 100 bases:

>100_bases
TGTTTCCTTTTCCACGCTATAAGCCCTTAAATGTTGTTCTTTTTTTGTCTATATTTGATATTGAAAATTCTCTTCTTGAA
ATTACGTTAAAACTTTCATT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1049; Mature: 1049

Protein sequence:

>1049_residues
MKPLTGNYDPKKIEDEIISFWEENKIYNKLRDIVSKRREKFLFIDGPPYPSSPTPHIGTIWNKVIKDCILRYERLLGKKV
HDQPGYDTHGLPIEVATERLLGILNKQEIIDKIGVENFINKCKEFALSNATKMTQNFKDVGVFMDWERPYYTLDPSYISS
SWSVIKKAYEKGMLDKGTAVLHWCPRCETTLSDYEVSEYRDLEDPSIYVKFKIKGEENRYLLIWTTTPWTIPSNVFVMVN
KDYDYADVEVNGEVLVLAKDRIEAVMKEASITNYKVLRTYKGSELIGVKYKHPLRDFVSAQTKLDDFHQVVDAGNVVTLT
DGTGLVHAATGHGEEDFLIGQKYGFPVVMFVNDRGEFTEEGGKYKGLKVRDASKVIINDLKSKNALFFEGKIVHRYPVCW
RCKTPLVLRAIDQWFIRVTKIKDEMLKEIENVNWIPDWGKSRISNMVKELRDWVISRQRFWGTPLPIWICEKCNNVIVVG
SREDLESIAIDSVPNDLHRPWIDNVRVKCNKCGGVAKRIADVADVWFDSGVAFFASLGKDWQEKWKELGPVDLVLEGHDQ
LRGWFFSLLRSGLILLDKAPYVSVLVHGFMLDEQGREMHKSLGNYVEPSVVIQRYGRDILRLWLLRNTTWEDARFSWRAL
ELTKRDLQIIWNTYVFASMYMNLDNFEPVKYTLDDVIKYAKIEDLWILSRFNSMLKKVNESMKNYKVHEMANYLINFLVE
DVSRFYIRLIRKRAWIEANTQDKIAMYYILYFILKQWIILASTIIPFISEKIYKSFVVNPKESVSMESSINYDERFIDNE
LERAFEVAREINEASLNARAKAGIKLRWPLAKVYIFVEDEDTLAKVNRIKDVLLSLLNAKDIEISKIEGFKSFSKYKVEP
NRSIIGKEYKSMSPKILDYIRNNSDIIAIDILNKKQHVARIDNVDVILNTSHVIISEETIEGYVSSKFAQGIVVISKEIS
ESEEEEGLVRDIIRRIQFMRKQLKLNVVDYIEISIKAPEERVKTIQKWEEFIKSETRGNKVILGDPKGDIVMDWDIEGES
YIIGIKKST

Sequences:

>Translated_1049_residues
MKPLTGNYDPKKIEDEIISFWEENKIYNKLRDIVSKRREKFLFIDGPPYPSSPTPHIGTIWNKVIKDCILRYERLLGKKV
HDQPGYDTHGLPIEVATERLLGILNKQEIIDKIGVENFINKCKEFALSNATKMTQNFKDVGVFMDWERPYYTLDPSYISS
SWSVIKKAYEKGMLDKGTAVLHWCPRCETTLSDYEVSEYRDLEDPSIYVKFKIKGEENRYLLIWTTTPWTIPSNVFVMVN
KDYDYADVEVNGEVLVLAKDRIEAVMKEASITNYKVLRTYKGSELIGVKYKHPLRDFVSAQTKLDDFHQVVDAGNVVTLT
DGTGLVHAATGHGEEDFLIGQKYGFPVVMFVNDRGEFTEEGGKYKGLKVRDASKVIINDLKSKNALFFEGKIVHRYPVCW
RCKTPLVLRAIDQWFIRVTKIKDEMLKEIENVNWIPDWGKSRISNMVKELRDWVISRQRFWGTPLPIWICEKCNNVIVVG
SREDLESIAIDSVPNDLHRPWIDNVRVKCNKCGGVAKRIADVADVWFDSGVAFFASLGKDWQEKWKELGPVDLVLEGHDQ
LRGWFFSLLRSGLILLDKAPYVSVLVHGFMLDEQGREMHKSLGNYVEPSVVIQRYGRDILRLWLLRNTTWEDARFSWRAL
ELTKRDLQIIWNTYVFASMYMNLDNFEPVKYTLDDVIKYAKIEDLWILSRFNSMLKKVNESMKNYKVHEMANYLINFLVE
DVSRFYIRLIRKRAWIEANTQDKIAMYYILYFILKQWIILASTIIPFISEKIYKSFVVNPKESVSMESSINYDERFIDNE
LERAFEVAREINEASLNARAKAGIKLRWPLAKVYIFVEDEDTLAKVNRIKDVLLSLLNAKDIEISKIEGFKSFSKYKVEP
NRSIIGKEYKSMSPKILDYIRNNSDIIAIDILNKKQHVARIDNVDVILNTSHVIISEETIEGYVSSKFAQGIVVISKEIS
ESEEEEGLVRDIIRRIQFMRKQLKLNVVDYIEISIKAPEERVKTIQKWEEFIKSETRGNKVILGDPKGDIVMDWDIEGES
YIIGIKKST
>Mature_1049_residues
MKPLTGNYDPKKIEDEIISFWEENKIYNKLRDIVSKRREKFLFIDGPPYPSSPTPHIGTIWNKVIKDCILRYERLLGKKV
HDQPGYDTHGLPIEVATERLLGILNKQEIIDKIGVENFINKCKEFALSNATKMTQNFKDVGVFMDWERPYYTLDPSYISS
SWSVIKKAYEKGMLDKGTAVLHWCPRCETTLSDYEVSEYRDLEDPSIYVKFKIKGEENRYLLIWTTTPWTIPSNVFVMVN
KDYDYADVEVNGEVLVLAKDRIEAVMKEASITNYKVLRTYKGSELIGVKYKHPLRDFVSAQTKLDDFHQVVDAGNVVTLT
DGTGLVHAATGHGEEDFLIGQKYGFPVVMFVNDRGEFTEEGGKYKGLKVRDASKVIINDLKSKNALFFEGKIVHRYPVCW
RCKTPLVLRAIDQWFIRVTKIKDEMLKEIENVNWIPDWGKSRISNMVKELRDWVISRQRFWGTPLPIWICEKCNNVIVVG
SREDLESIAIDSVPNDLHRPWIDNVRVKCNKCGGVAKRIADVADVWFDSGVAFFASLGKDWQEKWKELGPVDLVLEGHDQ
LRGWFFSLLRSGLILLDKAPYVSVLVHGFMLDEQGREMHKSLGNYVEPSVVIQRYGRDILRLWLLRNTTWEDARFSWRAL
ELTKRDLQIIWNTYVFASMYMNLDNFEPVKYTLDDVIKYAKIEDLWILSRFNSMLKKVNESMKNYKVHEMANYLINFLVE
DVSRFYIRLIRKRAWIEANTQDKIAMYYILYFILKQWIILASTIIPFISEKIYKSFVVNPKESVSMESSINYDERFIDNE
LERAFEVAREINEASLNARAKAGIKLRWPLAKVYIFVEDEDTLAKVNRIKDVLLSLLNAKDIEISKIEGFKSFSKYKVEP
NRSIIGKEYKSMSPKILDYIRNNSDIIAIDILNKKQHVARIDNVDVILNTSHVIISEETIEGYVSSKFAQGIVVISKEIS
ESEEEEGLVRDIIRRIQFMRKQLKLNVVDYIEISIKAPEERVKTIQKWEEFIKSETRGNKVILGDPKGDIVMDWDIEGES
YIIGIKKST

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1044, Percent_Identity=30.2681992337165, Blast_Score=489, Evalue=1e-138,
Organism=Homo sapiens, GI94721241, Length=1044, Percent_Identity=30.2681992337165, Blast_Score=489, Evalue=1e-138,
Organism=Homo sapiens, GI46852147, Length=828, Percent_Identity=29.4685990338164, Blast_Score=337, Evalue=4e-92,
Organism=Homo sapiens, GI5454158, Length=842, Percent_Identity=22.209026128266, Blast_Score=170, Evalue=7e-42,
Organism=Homo sapiens, GI268370293, Length=899, Percent_Identity=20.8008898776418, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI268370297, Length=899, Percent_Identity=20.8008898776418, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI268370295, Length=853, Percent_Identity=20.9847596717468, Blast_Score=147, Evalue=7e-35,
Organism=Homo sapiens, GI7661872, Length=234, Percent_Identity=29.4871794871795, Blast_Score=71, Evalue=5e-12,
Organism=Escherichia coli, GI2367096, Length=887, Percent_Identity=31.5670800450958, Blast_Score=430, Evalue=1e-121,
Organism=Escherichia coli, GI1790708, Length=937, Percent_Identity=21.6648879402348, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1786861, Length=770, Percent_Identity=22.0779220779221, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17541896, Length=1007, Percent_Identity=30.6852035749752, Blast_Score=476, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI71980946, Length=791, Percent_Identity=28.5714285714286, Blast_Score=285, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17510661, Length=930, Percent_Identity=22.5806451612903, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI72001587, Length=809, Percent_Identity=21.0135970333745, Blast_Score=147, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1016, Percent_Identity=31.3976377952756, Blast_Score=508, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6325217, Length=822, Percent_Identity=28.1021897810219, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6321531, Length=925, Percent_Identity=22.1621621621622, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28574730, Length=1021, Percent_Identity=29.4809010773751, Blast_Score=457, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24668547, Length=1021, Percent_Identity=29.4809010773751, Blast_Score=457, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24668543, Length=1021, Percent_Identity=29.4809010773751, Blast_Score=457, Evalue=1e-128,
Organism=Drosophila melanogaster, GI281366294, Length=836, Percent_Identity=28.4688995215311, Blast_Score=315, Evalue=1e-85,
Organism=Drosophila melanogaster, GI17864482, Length=867, Percent_Identity=23.4140715109573, Blast_Score=206, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24653289, Length=867, Percent_Identity=23.4140715109573, Blast_Score=206, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21355675, Length=939, Percent_Identity=21.9382321618743, Blast_Score=199, Evalue=6e-51,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_SULIA (C3N5S5)

Other databases:

- EMBL:   CP001401
- RefSeq:   YP_002843395.1
- GeneID:   7814234
- GenomeReviews:   CP001401_GR
- KEGG:   sim:M1627_1468
- OMA:   DCHGLPA
- ProtClustDB:   PRK06039
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 121985; Mature: 121985

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 600-600

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLTGNYDPKKIEDEIISFWEENKIYNKLRDIVSKRREKFLFIDGPPYPSSPTPHIGTI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHH
WNKVIKDCILRYERLLGKKVHDQPGYDTHGLPIEVATERLLGILNKQEIIDKIGVENFIN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH
KCKEFALSNATKMTQNFKDVGVFMDWERPYYTLDPSYISSSWSVIKKAYEKGMLDKGTAV
HHHHHHHCCHHHHHHCHHHCCEEEECCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCEE
LHWCPRCETTLSDYEVSEYRDLEDPSIYVKFKIKGEENRYLLIWTTTPWTIPSNVFVMVN
EEECCCCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCEEEEEE
KDYDYADVEVNGEVLVLAKDRIEAVMKEASITNYKVLRTYKGSELIGVKYKHPLRDFVSA
CCCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCHHHHHHHH
QTKLDDFHQVVDAGNVVTLTDGTGLVHAATGHGEEDFLIGQKYGFPVVMFVNDRGEFTEE
HHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCEEEECCCCCEEEEEECCCCCCCCC
GGKYKGLKVRDASKVIINDLKSKNALFFEGKIVHRYPVCWRCKTPLVLRAIDQWFIRVTK
CCCCCCEEECCCHHHHHHHHCCCCEEEEECEEEEECCEEEECCCHHHHHHHHHHHHHHHH
IKDEMLKEIENVNWIPDWGKSRISNMVKELRDWVISRQRFWGTPLPIWICEKCNNVIVVG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEE
SREDLESIAIDSVPNDLHRPWIDNVRVKCNKCGGVAKRIADVADVWFDSGVAFFASLGKD
CCHHHHHHHHCCCCCHHCCCCCCCCEEEEHHCCHHHHHHHHHHHHHHHCHHHHHHHHCHH
WQEKWKELGPVDLVLEGHDQLRGWFFSLLRSGLILLDKAPYVSVLVHGFMLDEQGREMHK
HHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCHHHHHHHH
SLGNYVEPSVVIQRYGRDILRLWLLRNTTWEDARFSWRALELTKRDLQIIWNTYVFASMY
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MNLDNFEPVKYTLDDVIKYAKIEDLWILSRFNSMLKKVNESMKNYKVHEMANYLINFLVE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DVSRFYIRLIRKRAWIEANTQDKIAMYYILYFILKQWIILASTIIPFISEKIYKSFVVNP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KESVSMESSINYDERFIDNELERAFEVAREINEASLNARAKAGIKLRWPLAKVYIFVEDE
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEECCEEEEEEEECCC
DTLAKVNRIKDVLLSLLNAKDIEISKIEGFKSFSKYKVEPNRSIIGKEYKSMSPKILDYI
HHHHHHHHHHHHHHHHHCCCCCEEHHHHCHHHHHHEECCCCCCHHHHHHHHCCHHHHHHH
RNNSDIIAIDILNKKQHVARIDNVDVILNTSHVIISEETIEGYVSSKFAQGIVVISKEIS
CCCCCEEEEEEECCHHHHHHCCCEEEEEECCEEEEEHHHHHHHHHHHHHCCEEEEEHHHC
ESEEEEGLVRDIIRRIQFMRKQLKLNVVDYIEISIKAPEERVKTIQKWEEFIKSETRGNK
CCHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCE
VILGDPKGDIVMDWDIEGESYIIGIKKST
EEEECCCCCEEEEEECCCCEEEEEEECCC
>Mature Secondary Structure
MKPLTGNYDPKKIEDEIISFWEENKIYNKLRDIVSKRREKFLFIDGPPYPSSPTPHIGTI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHH
WNKVIKDCILRYERLLGKKVHDQPGYDTHGLPIEVATERLLGILNKQEIIDKIGVENFIN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH
KCKEFALSNATKMTQNFKDVGVFMDWERPYYTLDPSYISSSWSVIKKAYEKGMLDKGTAV
HHHHHHHCCHHHHHHCHHHCCEEEECCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCEE
LHWCPRCETTLSDYEVSEYRDLEDPSIYVKFKIKGEENRYLLIWTTTPWTIPSNVFVMVN
EEECCCCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCEEEEEE
KDYDYADVEVNGEVLVLAKDRIEAVMKEASITNYKVLRTYKGSELIGVKYKHPLRDFVSA
CCCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCHHHHHHHH
QTKLDDFHQVVDAGNVVTLTDGTGLVHAATGHGEEDFLIGQKYGFPVVMFVNDRGEFTEE
HHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCEEEECCCCCEEEEEECCCCCCCCC
GGKYKGLKVRDASKVIINDLKSKNALFFEGKIVHRYPVCWRCKTPLVLRAIDQWFIRVTK
CCCCCCEEECCCHHHHHHHHCCCCEEEEECEEEEECCEEEECCCHHHHHHHHHHHHHHHH
IKDEMLKEIENVNWIPDWGKSRISNMVKELRDWVISRQRFWGTPLPIWICEKCNNVIVVG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEE
SREDLESIAIDSVPNDLHRPWIDNVRVKCNKCGGVAKRIADVADVWFDSGVAFFASLGKD
CCHHHHHHHHCCCCCHHCCCCCCCCEEEEHHCCHHHHHHHHHHHHHHHCHHHHHHHHCHH
WQEKWKELGPVDLVLEGHDQLRGWFFSLLRSGLILLDKAPYVSVLVHGFMLDEQGREMHK
HHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCHHHHHHHH
SLGNYVEPSVVIQRYGRDILRLWLLRNTTWEDARFSWRALELTKRDLQIIWNTYVFASMY
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MNLDNFEPVKYTLDDVIKYAKIEDLWILSRFNSMLKKVNESMKNYKVHEMANYLINFLVE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DVSRFYIRLIRKRAWIEANTQDKIAMYYILYFILKQWIILASTIIPFISEKIYKSFVVNP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KESVSMESSINYDERFIDNELERAFEVAREINEASLNARAKAGIKLRWPLAKVYIFVEDE
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEECCEEEEEEEECCC
DTLAKVNRIKDVLLSLLNAKDIEISKIEGFKSFSKYKVEPNRSIIGKEYKSMSPKILDYI
HHHHHHHHHHHHHHHHHCCCCCEEHHHHCHHHHHHEECCCCCCHHHHHHHHCCHHHHHHH
RNNSDIIAIDILNKKQHVARIDNVDVILNTSHVIISEETIEGYVSSKFAQGIVVISKEIS
CCCCCEEEEEEECCHHHHHHCCCEEEEEECCEEEEEHHHHHHHHHHHHHCCEEEEEHHHC
ESEEEEGLVRDIIRRIQFMRKQLKLNVVDYIEISIKAPEERVKTIQKWEEFIKSETRGNK
CCHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCE
VILGDPKGDIVMDWDIEGESYIIGIKKST
EEEECCCCCEEEEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA