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The map label for this gene is 227827543

Identifier: 227827543

GI number: 227827543

Start: 1209864

End: 1210949

Strand: Direct

Name: 227827543

Synonym: M1425_1270

Alternate gene names: NA

Gene position: 1209864-1210949 (Clockwise)

Preceding gene: 227827542

Following gene: 227827544

Centisome position: 46.38

GC content: 36.56

Gene sequence:

>1086_bases
ATGTACAATATGCAAAGTAATTTAAGGATCGATACAGTAAGTGAGATATTTAAAGAGTTACAAAAAGAGAAATACCACAT
CATTGGCACTCACAGTGCATATAAAAAATGTCATTGGACTCATTCTGCTCTTGTAGCTAATAGATCTTGCTATAAGGGCA
AATTCTACGGAATTGAGAGTCATAGATGCGTACAAATGACTCCAACTGCAGCCTGGTGCTGGTTTAGATGCGTACATTGT
TGGAGATTAGAACCAGAGGATGTTGGACTAGAGTGGGACGATACGAAAATGCCCGCATATGATGATCCTGAATATATTGT
AGAGAGGAGTATAGAAGAACATAAGAAGGCCGTTTCTGGATATCTAGGAAGAAATGATGTTAACATCCAAAAGGTAAAAG
ATGCGATGAGACCCGCGCATGTTGCAATAAGTTTGACTGGAGAACCTACACTTTATGAGAAACTTGGTGATCTTATAAAG
GAGTATCATAAAAGAGGAATGACAACCTTTCTTGTAACAAGTGGTGTAAGACCAGATATATTAGCAAGCTTAGAAGAAGA
GCCTACTCAGTTATTTGTATCTCTACAAGCTCCGAATGAGATAAAACACAAGATGATTAATAGACCAGTAGTTGCTAATT
CTTGGCAATTAGTTATGAAGACTTTAGAGATCTTACCTAGTTTTAGTTCTCCAACTGTGATAAGATTTACAATGATAAAG
GGATACAATATGAGTGAGCAAGATGCAAGAGAATTTGCGAAGTTAATGGAAATTGCAATGCCCACATATATAGAAATTAA
AGCTTATATGCACGTTGGACCATCAACCTATAGATTAAGTAGAGATGCGATGCCAAAACATAAAGAGATAAGAGAATTCG
CAAAAACCTTAGCACAATACACTGGATATAAAATCTTATCAGAGCACGTGCCCAGTAGAATAGTTCTTCTAAGTAAATTG
GATAAGCCAATTAAGATTGGAAATGCGTGGAATGAGAAATGGGATTGGTCTACTATTGATATAGAAGATGATATGAGTGG
AGAATATAAGGAAGCAGAACAAGGTTGTACAGAGGGATCAACTTGA

Upstream 100 bases:

>100_bases
AATTAACATTTCATCCTATATAGAGAGAAATGTTACAAAATTGTACAATTTAACAGCACCAATTAAGATCTAATAATTTT
TTAATCCTATATGCGGTAGA

Downstream 100 bases:

>100_bases
AAAGATGAGTCAAACGCTTGTATATTAGCTAAAATTATAGCCTATTCAAAGGGCAAATCATACGTAACGCAGTCAGAGCT
AGCTAAGATGCTCAATTTCT

Product: tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MYNMQSNLRIDTVSEIFKELQKEKYHIIGTHSAYKKCHWTHSALVANRSCYKGKFYGIESHRCVQMTPTAAWCWFRCVHC
WRLEPEDVGLEWDDTKMPAYDDPEYIVERSIEEHKKAVSGYLGRNDVNIQKVKDAMRPAHVAISLTGEPTLYEKLGDLIK
EYHKRGMTTFLVTSGVRPDILASLEEEPTQLFVSLQAPNEIKHKMINRPVVANSWQLVMKTLEILPSFSSPTVIRFTMIK
GYNMSEQDAREFAKLMEIAMPTYIEIKAYMHVGPSTYRLSRDAMPKHKEIREFAKTLAQYTGYKILSEHVPSRIVLLSKL
DKPIKIGNAWNEKWDWSTIDIEDDMSGEYKEAEQGCTEGST

Sequences:

>Translated_361_residues
MYNMQSNLRIDTVSEIFKELQKEKYHIIGTHSAYKKCHWTHSALVANRSCYKGKFYGIESHRCVQMTPTAAWCWFRCVHC
WRLEPEDVGLEWDDTKMPAYDDPEYIVERSIEEHKKAVSGYLGRNDVNIQKVKDAMRPAHVAISLTGEPTLYEKLGDLIK
EYHKRGMTTFLVTSGVRPDILASLEEEPTQLFVSLQAPNEIKHKMINRPVVANSWQLVMKTLEILPSFSSPTVIRFTMIK
GYNMSEQDAREFAKLMEIAMPTYIEIKAYMHVGPSTYRLSRDAMPKHKEIREFAKTLAQYTGYKILSEHVPSRIVLLSKL
DKPIKIGNAWNEKWDWSTIDIEDDMSGEYKEAEQGCTEGST
>Mature_361_residues
MYNMQSNLRIDTVSEIFKELQKEKYHIIGTHSAYKKCHWTHSALVANRSCYKGKFYGIESHRCVQMTPTAAWCWFRCVHC
WRLEPEDVGLEWDDTKMPAYDDPEYIVERSIEEHKKAVSGYLGRNDVNIQKVKDAMRPAHVAISLTGEPTLYEKLGDLIK
EYHKRGMTTFLVTSGVRPDILASLEEEPTQLFVSLQAPNEIKHKMINRPVVANSWQLVMKTLEILPSFSSPTVIRFTMIK
GYNMSEQDAREFAKLMEIAMPTYIEIKAYMHVGPSTYRLSRDAMPKHKEIREFAKTLAQYTGYKILSEHVPSRIVLLSKL
DKPIKIGNAWNEKWDWSTIDIEDDMSGEYKEAEQGCTEGST

Specific function: Unknown

COG id: COG0731

COG function: function code C; Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0026 family [H]

Homologues:

Organism=Homo sapiens, GI50726981, Length=335, Percent_Identity=34.9253731343284, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI224282123, Length=307, Percent_Identity=30.9446254071661, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI224282125, Length=273, Percent_Identity=31.8681318681319, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6325049, Length=333, Percent_Identity=33.033033033033, Blast_Score=187, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR013917 [H]

Pfam domain/function: PF04055 Radical_SAM; PF08608 Wyosine_form [H]

EC number: NA

Molecular weight: Translated: 41730; Mature: 41730

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNMQSNLRIDTVSEIFKELQKEKYHIIGTHSAYKKCHWTHSALVANRSCYKGKFYGIES
CCCCCCCCEEHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCC
HRCVQMTPTAAWCWFRCVHCWRLEPEDVGLEWDDTKMPAYDDPEYIVERSIEEHKKAVSG
CCEEEECCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YLGRNDVNIQKVKDAMRPAHVAISLTGEPTLYEKLGDLIKEYHKRGMTTFLVTSGVRPDI
CCCCCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHH
LASLEEEPTQLFVSLQAPNEIKHKMINRPVVANSWQLVMKTLEILPSFSSPTVIRFTMIK
HHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
GYNMSEQDAREFAKLMEIAMPTYIEIKAYMHVGPSTYRLSRDAMPKHKEIREFAKTLAQY
CCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHH
TGYKILSEHVPSRIVLLSKLDKPIKIGNAWNEKWDWSTIDIEDDMSGEYKEAEQGCTEGS
HCHHHHHHHCCHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCC
T
C
>Mature Secondary Structure
MYNMQSNLRIDTVSEIFKELQKEKYHIIGTHSAYKKCHWTHSALVANRSCYKGKFYGIES
CCCCCCCCEEHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCC
HRCVQMTPTAAWCWFRCVHCWRLEPEDVGLEWDDTKMPAYDDPEYIVERSIEEHKKAVSG
CCEEEECCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YLGRNDVNIQKVKDAMRPAHVAISLTGEPTLYEKLGDLIKEYHKRGMTTFLVTSGVRPDI
CCCCCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHH
LASLEEEPTQLFVSLQAPNEIKHKMINRPVVANSWQLVMKTLEILPSFSSPTVIRFTMIK
HHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
GYNMSEQDAREFAKLMEIAMPTYIEIKAYMHVGPSTYRLSRDAMPKHKEIREFAKTLAQY
CCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHH
TGYKILSEHVPSRIVLLSKLDKPIKIGNAWNEKWDWSTIDIEDDMSGEYKEAEQGCTEGS
HCHHHHHHHCCHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]