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The map label for this gene is rpiA [H]

Identifier: 227827517

GI number: 227827517

Start: 1183694

End: 1184377

Strand: Direct

Name: rpiA [H]

Synonym: M1425_1244

Alternate gene names: 227827517

Gene position: 1183694-1184377 (Clockwise)

Preceding gene: 227827515

Following gene: 227827532

Centisome position: 45.37

GC content: 34.5

Gene sequence:

>684_bases
GTGGATCCAAAGGAATTATTGGCAACGTATACTTTGAACTATCTAAGAGAAAAGAAGATAATAGGTGTTGGTACAGGAAA
AACTGTTAAAAAATTGATAGAAGTTTTGAGTAAAGAAGAAAATCTTAAAGAAACTGTATTGTTCGTTGCGAGTTCGCTCG
ATACTGAAATCGAATTGAGTAAACACGGTTTTAAAGTAATTTCACTCCTTTCCGCTATTCAACCTGAAATTTACGTTGAT
AGTTTCGATGTAGTTACCAAAGACGGTATAATGATAAAGGGTGGAGGAGGTGCCTTGCTTAGAGAGAAGCTTTTAACATA
TTTTTCTAAGTATAGGATTTTTATAGGAGAATTCAATAAGTTAAAGGACTCTAAACTAATTGACGTTCCAATTGAGGTCG
TAAGCGTCGGCGTAAGTTATGTCAAAGATAAGCTAGAGAAAATGGGATTTGCTGTAAAAATAAGAGAGGGAAGCGGTAAA
ATGGGACCAATTATTTCAGATAATGGAAATGCGATTTTAGATGTTTCTGTTAAGACTGAAAATTTATGCGAGTTTGACAG
AATGATAAAGACCATTCCATCAGTAGTAGAAACTGGGATTTTCTGTAAGGAATTATATAATAAGATAATATTGGCTAATG
AAGAAGGTAGGATTGAGGAAATGTATGCGGGGGACGGGATTTGA

Upstream 100 bases:

>100_bases
TAATTTGTTTATAAGTGATGAGCTTCCAGGCTTAGATCGATGAAGAGGGATGTGCAAACGCTGAGTTAGGTTTTATATTT
ACTTTACCAACCATTTACTC

Downstream 100 bases:

>100_bases
ACCCGCGAAGGCCTTCGCCAGCGGATCTCTTACTAAAGGGTCTTGAGTCCGCCCCCTTTGACCAGCTCGGGCACCCCCGC
ACATTTTAAATATAAACTCG

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MDPKELLATYTLNYLREKKIIGVGTGKTVKKLIEVLSKEENLKETVLFVASSLDTEIELSKHGFKVISLLSAIQPEIYVD
SFDVVTKDGIMIKGGGGALLREKLLTYFSKYRIFIGEFNKLKDSKLIDVPIEVVSVGVSYVKDKLEKMGFAVKIREGSGK
MGPIISDNGNAILDVSVKTENLCEFDRMIKTIPSVVETGIFCKELYNKIILANEEGRIEEMYAGDGI

Sequences:

>Translated_227_residues
MDPKELLATYTLNYLREKKIIGVGTGKTVKKLIEVLSKEENLKETVLFVASSLDTEIELSKHGFKVISLLSAIQPEIYVD
SFDVVTKDGIMIKGGGGALLREKLLTYFSKYRIFIGEFNKLKDSKLIDVPIEVVSVGVSYVKDKLEKMGFAVKIREGSGK
MGPIISDNGNAILDVSVKTENLCEFDRMIKTIPSVVETGIFCKELYNKIILANEEGRIEEMYAGDGI
>Mature_227_residues
MDPKELLATYTLNYLREKKIIGVGTGKTVKKLIEVLSKEENLKETVLFVASSLDTEIELSKHGFKVISLLSAIQPEIYVD
SFDVVTKDGIMIKGGGGALLREKLLTYFSKYRIFIGEFNKLKDSKLIDVPIEVVSVGVSYVKDKLEKMGFAVKIREGSGK
MGPIISDNGNAILDVSVKTENLCEFDRMIKTIPSVVETGIFCKELYNKIILANEEGRIEEMYAGDGI

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=198, Percent_Identity=30.8080808080808, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=31.3364055299539, Blast_Score=87, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17551758, Length=220, Percent_Identity=29.5454545454545, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324669, Length=225, Percent_Identity=29.3333333333333, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281364072, Length=197, Percent_Identity=30.9644670050761, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 25226; Mature: 25226

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPKELLATYTLNYLREKKIIGVGTGKTVKKLIEVLSKEENLKETVLFVASSLDTEIELS
CCHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEH
KHGFKVISLLSAIQPEIYVDSFDVVTKDGIMIKGGGGALLREKLLTYFSKYRIFIGEFNK
HHHHHHHHHHHHHCCCEEECCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHEEECCCC
LKDSKLIDVPIEVVSVGVSYVKDKLEKMGFAVKIREGSGKMGPIISDNGNAILDVSVKTE
CCCCCEEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCEEEEEEECCH
NLCEFDRMIKTIPSVVETGIFCKELYNKIILANEEGRIEEMYAGDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHCCCCC
>Mature Secondary Structure
MDPKELLATYTLNYLREKKIIGVGTGKTVKKLIEVLSKEENLKETVLFVASSLDTEIELS
CCHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEH
KHGFKVISLLSAIQPEIYVDSFDVVTKDGIMIKGGGGALLREKLLTYFSKYRIFIGEFNK
HHHHHHHHHHHHHCCCEEECCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHEEECCCC
LKDSKLIDVPIEVVSVGVSYVKDKLEKMGFAVKIREGSGKMGPIISDNGNAILDVSVKTE
CCCCCEEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCEEEEEEECCH
NLCEFDRMIKTIPSVVETGIFCKELYNKIILANEEGRIEEMYAGDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA