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The map label for this gene is hoxN [H]

Identifier: 227827484

GI number: 227827484

Start: 1138990

End: 1140084

Strand: Direct

Name: hoxN [H]

Synonym: M1425_1206

Alternate gene names: 227827484

Gene position: 1138990-1140084 (Clockwise)

Preceding gene: 227827482

Following gene: 227827485

Centisome position: 43.66

GC content: 35.71

Gene sequence:

>1095_bases
ATGATGGATAGACCATCCATATATGCGATGAGATCCATTCTCAATACGTTAACACAAACAATTAGTTACAAAAATTTAGT
CACCTTATCACTTTTCTACGTACTCAACGTATTACTAACAGCATTACTTTTTCTCTTCCTATACACATTACCACAAAAAC
CACTAACATTAAACACAGATAGCGGTGAGCTAATAGGAACCTTCATAACACTAGGAGTTTTATCATATACCTTTGGCTTA
AGACACGCAGTAGACGCTGATCACTTGGCAGCAATAGATAACGTAACTAGGAAAATGTTACAAGAAGGAAAGAATCCAGT
CTTCGTTGGCACTTTCTTCTCATTTGGTCATTCAACAGTAGTAATTTTACTATCCCTTGCAGTAATGACGGCTTCAAGGC
TGGTAACTAACTCATTACCGTCCCTCGAGAACACCGGAAATTTGATCGAGACACTAATAAGTGGAGGATTTCTTTATCTT
TTAGGCCTACTAAACACAATAGTACTCTACGAATTATACTCGTTTTATAAAGAAGGAAAATATGACAAACAAAAACTAGA
GGAAATATTGCAGAAAAGAGGTTTCATGAATAAATACTTTAACAAGTTGTTCAAAATAATAACAAACCAATGGCAAATGT
ACATTGTAGGATTCCTCTTTGGACTAGGATTTGACACCGCGACAGAAGTGGCAATACTATCAATATCGGCAATACTATCA
TCAACGTACATACACATACCAATCTACATAATCTTACTATACCCAATCCTATTTTCACTAGGAATGTCACTAGTTGACAC
TACTGATGGTCTATTCATGAGGTTCGCCTATGGCTGGGCATTCCTATCACCACTCAGAAAAATATGGTACAACTTAACGA
TGACACTAATATCAATTTTAATAGCGTTTGGAATAGGTACAATAGAGTTGTTAGGACTATTACAAGCTGAGTTCAACCTA
ACTGGATTATTCTGGGATCAAATAGCTGCGTTAAACAACGTTTACTGGGAAACAATAGGATATTATGTAATACTAACCTT
TGCCATAACTTGGATTGGGTCTGGAATGATTTACAGGATAAAGAAAATAGAGTAA

Upstream 100 bases:

>100_bases
CATTTTAGGTTATTGAAACCAGTAAAACTTGTACTATAACTTACACAAGACCATGAAATAACTGCCTTGTGGATTGCTTC
AGAATCGTAGAAAAATTTAT

Downstream 100 bases:

>100_bases
CCACAAAGGGTAAGGCAATTTTTCCTCATTAATTCCAAGAATACAGATAGAAGGAGGAATCTTTAAAACAATCTCGAACA
CTAAGTGATGCAAGCACTTT

Product: high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MMDRPSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLPQKPLTLNTDSGELIGTFITLGVLSYTFGL
RHAVDADHLAAIDNVTRKMLQEGKNPVFVGTFFSFGHSTVVILLSLAVMTASRLVTNSLPSLENTGNLIETLISGGFLYL
LGLLNTIVLYELYSFYKEGKYDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVAILSISAILS
STYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYNLTMTLISILIAFGIGTIELLGLLQAEFNL
TGLFWDQIAALNNVYWETIGYYVILTFAITWIGSGMIYRIKKIE

Sequences:

>Translated_364_residues
MMDRPSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLPQKPLTLNTDSGELIGTFITLGVLSYTFGL
RHAVDADHLAAIDNVTRKMLQEGKNPVFVGTFFSFGHSTVVILLSLAVMTASRLVTNSLPSLENTGNLIETLISGGFLYL
LGLLNTIVLYELYSFYKEGKYDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVAILSISAILS
STYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYNLTMTLISILIAFGIGTIELLGLLQAEFNL
TGLFWDQIAALNNVYWETIGYYVILTFAITWIGSGMIYRIKKIE
>Mature_364_residues
MMDRPSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLPQKPLTLNTDSGELIGTFITLGVLSYTFGL
RHAVDADHLAAIDNVTRKMLQEGKNPVFVGTFFSFGHSTVVILLSLAVMTASRLVTNSLPSLENTGNLIETLISGGFLYL
LGLLNTIVLYELYSFYKEGKYDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVAILSISAILS
STYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYNLTMTLISILIAFGIGTIELLGLLQAEFNL
TGLFWDQIAALNNVYWETIGYYVILTFAITWIGSGMIYRIKKIE

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 41249; Mature: 41249

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00079 MULTICOPPER_OXIDASE1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDRPSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLPQKPLTLNTD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
SGELIGTFITLGVLSYTFGLRHAVDADHLAAIDNVTRKMLQEGKNPVFVGTFFSFGHSTV
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCHHHH
VILLSLAVMTASRLVTNSLPSLENTGNLIETLISGGFLYLLGLLNTIVLYELYSFYKEGK
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
YDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVAILSISAILS
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
STYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYNLTMTLISIL
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFGIGTIELLGLLQAEFNLTGLFWDQIAALNNVYWETIGYYVILTFAITWIGSGMIYRI
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
KKIE
EECC
>Mature Secondary Structure
MMDRPSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLPQKPLTLNTD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
SGELIGTFITLGVLSYTFGLRHAVDADHLAAIDNVTRKMLQEGKNPVFVGTFFSFGHSTV
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCHHHH
VILLSLAVMTASRLVTNSLPSLENTGNLIETLISGGFLYLLGLLNTIVLYELYSFYKEGK
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
YDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVAILSISAILS
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
STYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYNLTMTLISIL
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFGIGTIELLGLLQAEFNLTGLFWDQIAALNNVYWETIGYYVILTFAITWIGSGMIYRI
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
KKIE
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]