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The map label for this gene is 227827447

Identifier: 227827447

GI number: 227827447

Start: 1103437

End: 1105731

Strand: Direct

Name: 227827447

Synonym: M1425_1167

Alternate gene names: NA

Gene position: 1103437-1105731 (Clockwise)

Preceding gene: 227827441

Following gene: 227827456

Centisome position: 42.3

GC content: 37.52

Gene sequence:

>2295_bases
ATGCAGTCAGTTAAGGGATTAAGAAGAGATTTACGGAAGACATCATTCATAGATTTACCCCTAATAGTAGGTCTTTCATT
AGTTTCGATATTAATTAGAAGCCTAAGTGCTAATTGGCCTTTAGCAGTTAACGAATTCGATCCTTGGTATCTTTTCTATA
ATGCATTATTGATAGCTCAAGTTCATGGAAATTGGTACGCAGTACCTCCAGACGTATTAGGTTGGTTACCATGGGGATAC
TTCATTGAATTGGGGAATACTATAGGTTTGCCCTTCTTAGTAGCATTAGCCTCTTTGCCCTTCTATGGAACTTACGGAGC
AAACGCAGTATATACGGTGGCAATATTTTCTGATATTTTGTTAGCTGGACTAGGAGTTGTAGCATCATATCTTTCGATAG
AGTCCATAACTAATAGCAGATTAGCTGGTTATATGGCAGCTGCAATAATCGCAGTTTCTCCTGCGTTAACATATAAGAAC
TTGTTAGGTGGTCTTCCTAAGACATCTTGGGGTGCAGTGTTTATCCTATTTGCAATTTTCCTCTTTAATCAAGGCTTAAA
GAAGAAGAACATCTGGTATGGTGTACCCGCAGGTTTTGTGTTATTTTTAGCCGAGATCTCTTGGGGAGGTTATACATATA
TTGACTTAAGTTTGCTCGTAGCAGCGTTCTTACTAATTTTACTGAATAGAAATGATGAGACTACTGCAAACTTGTACACA
ATAATGGTAGTTGTAACTTCATTTCTAACTTCATTAGCCCCAAATAATATAGGTTTCATGTCTGGGTTAGCACACGGCCT
ATCACTACTCTTAATTTCAGCAGTTCTTTATTTAGACTTATATCTATCTAAAACGCTACCTAAAGAAATCGTAGATTCAA
GAAATCTAATAGTAATTGCAGTACTAATTTTCATATTCACCATAGGATTATCTGGGCTATCAATACTAAGACCTACATCA
GCGCCAATACCATCAAGGTATTACGCTATAATAAACCCGTTTTATCAAGTTACAATACCGATAGATAAGACAGTAGCAGA
GTATATTCCCCAGCCGATAACTGCAATGATACAAGATTTCGGAATAGCACTATTTTTGTCAGTCATAGGGATGTATTACT
TGATAAGAAAAGGAAACCTAGTAGGTTTATGGTTATTGGTATTGGGAGTTGCTAGCATATTTGGCACATCACAACAGCCC
TACCTATTTAACTATACAGCCTATATGGTAGCTGCCTTAGGAGGTTTAGGAGTTTATTACATTGCAGATAACCTACTAAA
GGGAGTGAAAAATGGAAACAGCAGCAAAATTTTAGTAGGCTTTTTCTTAGCTATTGTAGGAATATCCTTAGTAGCAGATG
CTGGATTGGCAACACTAGCGAGCAATGAACCTCCGGCAATAACCAATGCTGCTACAAGCTTCTTAACAACTAACTACTCT
TGGGTATCTGCAGCAAATTGGATAAGAACCCATTCACCACAACACGCGTTTGTATTATCCTGGTGGGATTATGGGTATTG
GCTGGAGGTCTTGACAAATAGGAGCGTTATAGATGAAAATAATACGCTTAATGGTACACAAATTAAACTAATGGCAGAAA
TGTTCTTGAACAATGAAACTTTCGCAGCGAATGTCCTAGAAAAATATTTCCACCTGTATCCTTATGGTAGTCCAAACTAT
ACTATACCAGTTTATATAGTGGCATATGATGCTGTTACGCTAGTATATTCTGGCAATCAAGCCCAATGGTACGTAGGATA
CCCACCTAGTTTACCTAATGCGTTCTTTGGATATACAACAAGTTTAGGAGATATTGGAAAGGCTATGGGAGCAATGACAA
CAATAGCTGGATATCCTCTAGAAGAATACATAAACCTAACCGAATTAAATAATACAATAACACAAATAATTAATACCTAT
GCAACTACTAATCCAACTATTGCCCAAGCATTAGCTTCACAAGTTTCACAAGCTGAACCATTTGCATGGACCCCTAAAGC
ATATAACTCACTTATAGTCCAAATGTTCATTGAGAGTCTGTATCAAATAGGATACGGACAACCAATAGCTCCATTCACAA
CACAAATAATTCCTAGCAGTTCTGGATATATTATAACGGGATCTCCATTACCACGTGTTCAACTAATGTATTTCCAACCT
GCATATATAGCACTATTCCCGGTAGGAAATGGAGGTGCTGGAGGAGTTCCCTACACTACTTACATAATGGTCATGGTATA
CCAGTTTACACAGCCCGGTGTTATACTAAAACCTACAGTAGTAATCAACAGTTAA

Upstream 100 bases:

>100_bases
TATGAAGTTAGAGCTTTATTTTTAAAATGATTCTCTGTAAACTAAAACTGTATGCTTGGAATAAGTTTAATAAATGTATA
ATACTTAATACACTACAGCC

Downstream 100 bases:

>100_bases
GCTTTACTCCTTTTTTTAATTCAATCCTATATTTTACGTATTTATCTTCTGGAGAAAATCTAGATGGATGAGGAATCATA
GTCTTAGAGCCGCATACAGG

Product: oligosaccharyl transferase STT3 subunit

Products: NA

Alternate protein names: Dolichyl-Diphosphooligosaccharide-Protein Glycotransferase; Oligosaccharyl Transferase

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MQSVKGLRRDLRKTSFIDLPLIVGLSLVSILIRSLSANWPLAVNEFDPWYLFYNALLIAQVHGNWYAVPPDVLGWLPWGY
FIELGNTIGLPFLVALASLPFYGTYGANAVYTVAIFSDILLAGLGVVASYLSIESITNSRLAGYMAAAIIAVSPALTYKN
LLGGLPKTSWGAVFILFAIFLFNQGLKKKNIWYGVPAGFVLFLAEISWGGYTYIDLSLLVAAFLLILLNRNDETTANLYT
IMVVVTSFLTSLAPNNIGFMSGLAHGLSLLLISAVLYLDLYLSKTLPKEIVDSRNLIVIAVLIFIFTIGLSGLSILRPTS
APIPSRYYAIINPFYQVTIPIDKTVAEYIPQPITAMIQDFGIALFLSVIGMYYLIRKGNLVGLWLLVLGVASIFGTSQQP
YLFNYTAYMVAALGGLGVYYIADNLLKGVKNGNSSKILVGFFLAIVGISLVADAGLATLASNEPPAITNAATSFLTTNYS
WVSAANWIRTHSPQHAFVLSWWDYGYWLEVLTNRSVIDENNTLNGTQIKLMAEMFLNNETFAANVLEKYFHLYPYGSPNY
TIPVYIVAYDAVTLVYSGNQAQWYVGYPPSLPNAFFGYTTSLGDIGKAMGAMTTIAGYPLEEYINLTELNNTITQIINTY
ATTNPTIAQALASQVSQAEPFAWTPKAYNSLIVQMFIESLYQIGYGQPIAPFTTQIIPSSSGYIITGSPLPRVQLMYFQP
AYIALFPVGNGGAGGVPYTTYIMVMVYQFTQPGVILKPTVVINS

Sequences:

>Translated_764_residues
MQSVKGLRRDLRKTSFIDLPLIVGLSLVSILIRSLSANWPLAVNEFDPWYLFYNALLIAQVHGNWYAVPPDVLGWLPWGY
FIELGNTIGLPFLVALASLPFYGTYGANAVYTVAIFSDILLAGLGVVASYLSIESITNSRLAGYMAAAIIAVSPALTYKN
LLGGLPKTSWGAVFILFAIFLFNQGLKKKNIWYGVPAGFVLFLAEISWGGYTYIDLSLLVAAFLLILLNRNDETTANLYT
IMVVVTSFLTSLAPNNIGFMSGLAHGLSLLLISAVLYLDLYLSKTLPKEIVDSRNLIVIAVLIFIFTIGLSGLSILRPTS
APIPSRYYAIINPFYQVTIPIDKTVAEYIPQPITAMIQDFGIALFLSVIGMYYLIRKGNLVGLWLLVLGVASIFGTSQQP
YLFNYTAYMVAALGGLGVYYIADNLLKGVKNGNSSKILVGFFLAIVGISLVADAGLATLASNEPPAITNAATSFLTTNYS
WVSAANWIRTHSPQHAFVLSWWDYGYWLEVLTNRSVIDENNTLNGTQIKLMAEMFLNNETFAANVLEKYFHLYPYGSPNY
TIPVYIVAYDAVTLVYSGNQAQWYVGYPPSLPNAFFGYTTSLGDIGKAMGAMTTIAGYPLEEYINLTELNNTITQIINTY
ATTNPTIAQALASQVSQAEPFAWTPKAYNSLIVQMFIESLYQIGYGQPIAPFTTQIIPSSSGYIITGSPLPRVQLMYFQP
AYIALFPVGNGGAGGVPYTTYIMVMVYQFTQPGVILKPTVVINS
>Mature_764_residues
MQSVKGLRRDLRKTSFIDLPLIVGLSLVSILIRSLSANWPLAVNEFDPWYLFYNALLIAQVHGNWYAVPPDVLGWLPWGY
FIELGNTIGLPFLVALASLPFYGTYGANAVYTVAIFSDILLAGLGVVASYLSIESITNSRLAGYMAAAIIAVSPALTYKN
LLGGLPKTSWGAVFILFAIFLFNQGLKKKNIWYGVPAGFVLFLAEISWGGYTYIDLSLLVAAFLLILLNRNDETTANLYT
IMVVVTSFLTSLAPNNIGFMSGLAHGLSLLLISAVLYLDLYLSKTLPKEIVDSRNLIVIAVLIFIFTIGLSGLSILRPTS
APIPSRYYAIINPFYQVTIPIDKTVAEYIPQPITAMIQDFGIALFLSVIGMYYLIRKGNLVGLWLLVLGVASIFGTSQQP
YLFNYTAYMVAALGGLGVYYIADNLLKGVKNGNSSKILVGFFLAIVGISLVADAGLATLASNEPPAITNAATSFLTTNYS
WVSAANWIRTHSPQHAFVLSWWDYGYWLEVLTNRSVIDENNTLNGTQIKLMAEMFLNNETFAANVLEKYFHLYPYGSPNY
TIPVYIVAYDAVTLVYSGNQAQWYVGYPPSLPNAFFGYTTSLGDIGKAMGAMTTIAGYPLEEYINLTELNNTITQIINTY
ATTNPTIAQALASQVSQAEPFAWTPKAYNSLIVQMFIESLYQIGYGQPIAPFTTQIIPSSSGYIITGSPLPRVQLMYFQP
AYIALFPVGNGGAGGVPYTTYIMVMVYQFTQPGVILKPTVVINS

Specific function: Unknown

COG id: COG1287

COG function: function code R; Uncharacterized membrane protein, required for N-linked glycosylation

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI22749415, Length=590, Percent_Identity=21.6949152542373, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI30578410, Length=370, Percent_Identity=22.7027027027027, Blast_Score=67, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17555006, Length=578, Percent_Identity=23.1833910034602, Blast_Score=113, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6321416, Length=545, Percent_Identity=22.0183486238532, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129103, Length=593, Percent_Identity=23.2715008431703, Blast_Score=127, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 83692; Mature: 83692

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00251 TNF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVKGLRRDLRKTSFIDLPLIVGLSLVSILIRSLSANWPLAVNEFDPWYLFYNALLIAQ
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHEEE
VHGNWYAVPPDVLGWLPWGYFIELGNTIGLPFLVALASLPFYGTYGANAVYTVAIFSDIL
ECCCEEECCHHHHHHCCHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LAGLGVVASYLSIESITNSRLAGYMAAAIIAVSPALTYKNLLGGLPKTSWGAVFILFAIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LFNQGLKKKNIWYGVPAGFVLFLAEISWGGYTYIDLSLLVAAFLLILLNRNDETTANLYT
HHCCCCCCCCCEEECCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHH
IMVVVTSFLTSLAPNNIGFMSGLAHGLSLLLISAVLYLDLYLSKTLPKEIVDSRNLIVIA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHH
VLIFIFTIGLSGLSILRPTSAPIPSRYYAIINPFYQVTIPIDKTVAEYIPQPITAMIQDF
HHHHHHHHCCCCCEEECCCCCCCCCCHHEEECCEEEEEECHHHHHHHHCCCHHHHHHHHH
GIALFLSVIGMYYLIRKGNLVGLWLLVLGVASIFGTSQQPYLFNYTAYMVAALGGLGVYY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCHHHH
IADNLLKGVKNGNSSKILVGFFLAIVGISLVADAGLATLASNEPPAITNAATSFLTTNYS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHCCCCC
WVSAANWIRTHSPQHAFVLSWWDYGYWLEVLTNRSVIDENNTLNGTQIKLMAEMFLNNET
HHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHCCCH
FAANVLEKYFHLYPYGSPNYTIPVYIVAYDAVTLVYSGNQAQWYVGYPPSLPNAFFGYTT
HHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEEEEECCCEEEEEECCCCCCCCHHCCCC
SLGDIGKAMGAMTTIAGYPLEEYINLTELNNTITQIINTYATTNPTIAQALASQVSQAEP
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
FAWTPKAYNSLIVQMFIESLYQIGYGQPIAPFTTQIIPSSSGYIITGSPLPRVQLMYFQP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCCCCEEEECCCCCCEEEEEECC
AYIALFPVGNGGAGGVPYTTYIMVMVYQFTQPGVILKPTVVINS
EEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEECEEEECC
>Mature Secondary Structure
MQSVKGLRRDLRKTSFIDLPLIVGLSLVSILIRSLSANWPLAVNEFDPWYLFYNALLIAQ
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHEEE
VHGNWYAVPPDVLGWLPWGYFIELGNTIGLPFLVALASLPFYGTYGANAVYTVAIFSDIL
ECCCEEECCHHHHHHCCHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LAGLGVVASYLSIESITNSRLAGYMAAAIIAVSPALTYKNLLGGLPKTSWGAVFILFAIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LFNQGLKKKNIWYGVPAGFVLFLAEISWGGYTYIDLSLLVAAFLLILLNRNDETTANLYT
HHCCCCCCCCCEEECCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHH
IMVVVTSFLTSLAPNNIGFMSGLAHGLSLLLISAVLYLDLYLSKTLPKEIVDSRNLIVIA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHH
VLIFIFTIGLSGLSILRPTSAPIPSRYYAIINPFYQVTIPIDKTVAEYIPQPITAMIQDF
HHHHHHHHCCCCCEEECCCCCCCCCCHHEEECCEEEEEECHHHHHHHHCCCHHHHHHHHH
GIALFLSVIGMYYLIRKGNLVGLWLLVLGVASIFGTSQQPYLFNYTAYMVAALGGLGVYY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCHHHH
IADNLLKGVKNGNSSKILVGFFLAIVGISLVADAGLATLASNEPPAITNAATSFLTTNYS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHCCCCC
WVSAANWIRTHSPQHAFVLSWWDYGYWLEVLTNRSVIDENNTLNGTQIKLMAEMFLNNET
HHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHCCCH
FAANVLEKYFHLYPYGSPNYTIPVYIVAYDAVTLVYSGNQAQWYVGYPPSLPNAFFGYTT
HHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEEEEECCCEEEEEECCCCCCCCHHCCCC
SLGDIGKAMGAMTTIAGYPLEEYINLTELNNTITQIINTYATTNPTIAQALASQVSQAEP
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
FAWTPKAYNSLIVQMFIESLYQIGYGQPIAPFTTQIIPSSSGYIITGSPLPRVQLMYFQP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCCCCEEEECCCCCCEEEEEECC
AYIALFPVGNGGAGGVPYTTYIMVMVYQFTQPGVILKPTVVINS
EEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA