Click here to switch to the map view.

The map label for this gene is hdrB2 [H]

Identifier: 227826567

GI number: 227826567

Start: 137887

End: 138759

Strand: Direct

Name: hdrB2 [H]

Synonym: M1425_0157

Alternate gene names: 227826567

Gene position: 137887-138759 (Clockwise)

Preceding gene: 227826566

Following gene: 227826568

Centisome position: 5.29

GC content: 37.23

Gene sequence:

>873_bases
ATGAAAATAGCTTACTATCCTGGATGTGCAACTCATGGTTTATCTAAGGATGTAGATATAGCAACAAAAAAGGTAGCAGA
AGTACTTGGAGTTGAGCTGATAGAAGTACCAGATTGGAACTGTTGTGGTGGTGGATTTTATGACGAATATGATGAAGTTG
GTCATGTAGCTCTTAACTTAAGGAATTTATCACAAGTAGAAAAGATGGGTCTTACGAAGATGGTAACACCTTGTAGCGTA
TGTCTTCATAGCCATAGACTAGCAACATACAAATATAAGGAAGATAGAGATATTAAAAGAAAGACTGATAAAAGACTAGA
AGGCACTTCAGTTAAATATGAGGGAAAGGTGGATGCGGAACATATAGTTTGGGTTTTATTAAGAGATGTAGGAGTAGAGA
ATATTAAGAAACACGTTAAGAAAACTTTAACTGGACTTAAAGTAGGCACTTATTACGGATGTCAAATGCTAAGACCAGAA
CAAATAATGGGATTTGAGAAGGCATACAATCCCACTAGTTTATCTGAATTGGTTGCAGTAACTGGAGCTATACCAGTTCC
TTTCCCTACCATGACCTCATGTTGCGGATTTCCCCTAGTTGGAAGCAATCCTAAGGGCGCTTTAAAGTTAGCATTTAACG
TTCTTAATGGTGCCAAACAAGCTGGAGCTGATTTAGTAATACACCCGTGTAGTTTATGTCATCTTCAGCTGGACTCTTTA
CAGTTAAAGGTTAAGGCTGAATTTAACGTAAGTTGGACTATGCCTGCAATATATGTAACACAACTATTGGGTTTATCCTT
TGGTTTCAGTCCTGAAGAACTAGGAATAGGAAAGATTGCAATTGACGTATTACGAAATAAGGGAGTGATATAA

Upstream 100 bases:

>100_bases
TGTATATGTCGAGGGCAGGAAAGCTTAAGTACATATTAGTTCAAGAGAAACCCGTACAAAATATAAACGAAATTAAAAAG
ATAATAGGTGAGTGATAAGA

Downstream 100 bases:

>100_bases
ATGAGTGAGGAAATTAAGAAAATTATTCAAGATGTTGGAGGAAAGCCGGAGGAATGGATTAGTGTTTCCGAAAGGCCGGG
GAAGGAACCATTTGCTAAGG

Product: CoB--CoM heterodisulfide reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKIAYYPGCATHGLSKDVDIATKKVAEVLGVELIEVPDWNCCGGGFYDEYDEVGHVALNLRNLSQVEKMGLTKMVTPCSV
CLHSHRLATYKYKEDRDIKRKTDKRLEGTSVKYEGKVDAEHIVWVLLRDVGVENIKKHVKKTLTGLKVGTYYGCQMLRPE
QIMGFEKAYNPTSLSELVAVTGAIPVPFPTMTSCCGFPLVGSNPKGALKLAFNVLNGAKQAGADLVIHPCSLCHLQLDSL
QLKVKAEFNVSWTMPAIYVTQLLGLSFGFSPEELGIGKIAIDVLRNKGVI

Sequences:

>Translated_290_residues
MKIAYYPGCATHGLSKDVDIATKKVAEVLGVELIEVPDWNCCGGGFYDEYDEVGHVALNLRNLSQVEKMGLTKMVTPCSV
CLHSHRLATYKYKEDRDIKRKTDKRLEGTSVKYEGKVDAEHIVWVLLRDVGVENIKKHVKKTLTGLKVGTYYGCQMLRPE
QIMGFEKAYNPTSLSELVAVTGAIPVPFPTMTSCCGFPLVGSNPKGALKLAFNVLNGAKQAGADLVIHPCSLCHLQLDSL
QLKVKAEFNVSWTMPAIYVTQLLGLSFGFSPEELGIGKIAIDVLRNKGVI
>Mature_290_residues
MKIAYYPGCATHGLSKDVDIATKKVAEVLGVELIEVPDWNCCGGGFYDEYDEVGHVALNLRNLSQVEKMGLTKMVTPCSV
CLHSHRLATYKYKEDRDIKRKTDKRLEGTSVKYEGKVDAEHIVWVLLRDVGVENIKKHVKKTLTGLKVGTYYGCQMLRPE
QIMGFEKAYNPTSLSELVAVTGAIPVPFPTMTSCCGFPLVGSNPKGALKLAFNVLNGAKQAGADLVIHPCSLCHLQLDSL
QLKVKAEFNVSWTMPAIYVTQLLGLSFGFSPEELGIGKIAIDVLRNKGVI

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrB may have a function in energy transduction [H]

COG id: COG2048

COG function: function code C; Heterodisulfide reductase, subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017678
- InterPro:   IPR004017 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 31850; Mature: 31850

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAYYPGCATHGLSKDVDIATKKVAEVLGVELIEVPDWNCCGGGFYDEYDEVGHVALNL
CEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHEEEEH
RNLSQVEKMGLTKMVTPCSVCLHSHRLATYKYKEDRDIKRKTDKRLEGTSVKYEGKVDAE
HHHHHHHHHCHHHHHHHHHHHHHHCHHEEEEECCCCCHHHHHHCCCCCCCEEECCCCCHH
HIVWVLLRDVGVENIKKHVKKTLTGLKVGTYYGCQMLRPEQIMGFEKAYNPTSLSELVAV
HHHHHHHHHCCHHHHHHHHHHHHHHCEECHHHCCEECCHHHHHCHHHCCCCCHHHHHHHH
TGAIPVPFPTMTSCCGFPLVGSNPKGALKLAFNVLNGAKQAGADLVIHPCSLCHLQLDSL
HCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHEEEECCE
QLKVKAEFNVSWTMPAIYVTQLLGLSFGFSPEELGIGKIAIDVLRNKGVI
EEEEEEEEEEEECHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIAYYPGCATHGLSKDVDIATKKVAEVLGVELIEVPDWNCCGGGFYDEYDEVGHVALNL
CEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHEEEEH
RNLSQVEKMGLTKMVTPCSVCLHSHRLATYKYKEDRDIKRKTDKRLEGTSVKYEGKVDAE
HHHHHHHHHCHHHHHHHHHHHHHHCHHEEEEECCCCCHHHHHHCCCCCCCEEECCCCCHH
HIVWVLLRDVGVENIKKHVKKTLTGLKVGTYYGCQMLRPEQIMGFEKAYNPTSLSELVAV
HHHHHHHHHCCHHHHHHHHHHHHHHCEECHHHCCEECCHHHHHCHHHCCCCCHHHHHHHH
TGAIPVPFPTMTSCCGFPLVGSNPKGALKLAFNVLNGAKQAGADLVIHPCSLCHLQLDSL
HCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHEEEECCE
QLKVKAEFNVSWTMPAIYVTQLLGLSFGFSPEELGIGKIAIDVLRNKGVI
EEEEEEEEEEEECHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]