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The map label for this gene is lsrR [H]

Identifier: 227814217

GI number: 227814217

Start: 1490125

End: 1491075

Strand: Reverse

Name: lsrR [H]

Synonym: BAMEG_1625

Alternate gene names: 227814217

Gene position: 1491075-1490125 (Counterclockwise)

Preceding gene: 227814220

Following gene: 227814216

Centisome position: 28.51

GC content: 38.8

Gene sequence:

>951_bases
TTGAAAGGGATGAAAAGTATGACTCAGCTGAACTTTGAAGAGAATTTATTAACGAAAGTAGCTTGGTACTATTATAAGGA
CCAATTAACACAACAGGAGATCGCTTCACTTCTTCATATTTCAAGAAATAAAGTCGTCCGGTTATTAGATAAGGCGCGGA
GTGAAGGTATCGTTACATTTCACGTAAAAGGGACTGGTTTGCACTGTTTAAGTATTGAGCGTGACCTAATGAAAAAATTC
CACTTAAAAGATGCTTTTATTATCCCGACCCCATTAAACAATTATCACGATTCTCTCGGAAAAGCTGCTGCACAATATTT
AGAAACTCAGCTCCAGCAAGGCGATTTACTCGGTATTGGCTGGGGAGAAACAATTAGCAAAATGCTAGAAAACATTCATT
TCGAAAGTTCTATTAATCTCTCAATCGTAACGTTAACAGGCGGAGTAAATCACTATCTCCCGAGAAAACAAAACTATTTA
CATTACATGCAAGGTGATCTTCACATTATCCCTACGCCGTTTCTAGCGTCTACAACCGAAATGGCACAAAGTATTCTATC
AGAACCGAGCGTAAAAGATATGCTTCATGTCGCTTCACTTGCTCATACGGCTGTTGTCGGTATTGGAGGACTATCTCAAG
ATGCTACGATTGTAAAAGAAGAAAAATTAACTTTACGTGAGATGACATATATTCGTAGTCAAAACGGTGCTGGCGATATT
TTAGGACAGTTTTATGATACAAATGGCGGTTTATTAGAGCTCTCGCATCACAATCGTCTAATTGGCACGCCCCTCCCTGT
TTTGCGCAATATGAAGCATGTCGTCGGTGTTGCTGGAGGTACTGAAAAGATAGATGCAATTTATGGTGCCTTAAAAGGAA
AGTTTATTCATACATTAATTACCGATGAGGAAACTGCCCTTTCCTTATTACGAAAGGATGGTGATTGTTAA

Upstream 100 bases:

>100_bases
TCCTTTTTTATATCTAGAACACTTTTTTCTACGTACTATTAATCGCTTCAACTGGAATAAACAAAATATATGGTACATAT
GTTTAAGCTGTGGTCAATTG

Downstream 100 bases:

>100_bases
TGTCCAATTTATTAGCTTTCGATGCTGGTACAGGAAGTATTCGAGCAGTTCTTTTTGATTTACATGGTAATCAAATTGCA
GTAAGTCAAAAAGAATGGAT

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKGMKSMTQLNFEENLLTKVAWYYYKDQLTQQEIASLLHISRNKVVRLLDKARSEGIVTFHVKGTGLHCLSIERDLMKKF
HLKDAFIIPTPLNNYHDSLGKAAAQYLETQLQQGDLLGIGWGETISKMLENIHFESSINLSIVTLTGGVNHYLPRKQNYL
HYMQGDLHIIPTPFLASTTEMAQSILSEPSVKDMLHVASLAHTAVVGIGGLSQDATIVKEEKLTLREMTYIRSQNGAGDI
LGQFYDTNGGLLELSHHNRLIGTPLPVLRNMKHVVGVAGGTEKIDAIYGALKGKFIHTLITDEETALSLLRKDGDC

Sequences:

>Translated_316_residues
MKGMKSMTQLNFEENLLTKVAWYYYKDQLTQQEIASLLHISRNKVVRLLDKARSEGIVTFHVKGTGLHCLSIERDLMKKF
HLKDAFIIPTPLNNYHDSLGKAAAQYLETQLQQGDLLGIGWGETISKMLENIHFESSINLSIVTLTGGVNHYLPRKQNYL
HYMQGDLHIIPTPFLASTTEMAQSILSEPSVKDMLHVASLAHTAVVGIGGLSQDATIVKEEKLTLREMTYIRSQNGAGDI
LGQFYDTNGGLLELSHHNRLIGTPLPVLRNMKHVVGVAGGTEKIDAIYGALKGKFIHTLITDEETALSLLRKDGDC
>Mature_316_residues
MKGMKSMTQLNFEENLLTKVAWYYYKDQLTQQEIASLLHISRNKVVRLLDKARSEGIVTFHVKGTGLHCLSIERDLMKKF
HLKDAFIIPTPLNNYHDSLGKAAAQYLETQLQQGDLLGIGWGETISKMLENIHFESSINLSIVTLTGGVNHYLPRKQNYL
HYMQGDLHIIPTPFLASTTEMAQSILSEPSVKDMLHVASLAHTAVVGIGGLSQDATIVKEEKLTLREMTYIRSQNGAGDI
LGQFYDTNGGLLELSHHNRLIGTPLPVLRNMKHVVGVAGGTEKIDAIYGALKGKFIHTLITDEETALSLLRKDGDC

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=304, Percent_Identity=38.1578947368421, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87082414, Length=314, Percent_Identity=25.796178343949, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35151; Mature: 35151

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGMKSMTQLNFEENLLTKVAWYYYKDQLTQQEIASLLHISRNKVVRLLDKARSEGIVTF
CCCHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
HVKGTGLHCLSIERDLMKKFHLKDAFIIPTPLNNYHDSLGKAAAQYLETQLQQGDLLGIG
EEECCCEEEEHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEC
WGETISKMLENIHFESSINLSIVTLTGGVNHYLPRKQNYLHYMQGDLHIIPTPFLASTTE
CHHHHHHHHHHCCCCCCCCEEEEEEECCCHHCCCCCCCHHHHCCCCEEEECCCHHHHHHH
MAQSILSEPSVKDMLHVASLAHTAVVGIGGLSQDATIVKEEKLTLREMTYIRSQNGAGDI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCHH
LGQFYDTNGGLLELSHHNRLIGTPLPVLRNMKHVVGVAGGTEKIDAIYGALKGKFIHTLI
HHHEECCCCCEEEECCCCCCCCCCHHHHHCHHHHHCCCCCHHHHHHHHHHHCCCEEEEEE
TDEETALSLLRKDGDC
CCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKGMKSMTQLNFEENLLTKVAWYYYKDQLTQQEIASLLHISRNKVVRLLDKARSEGIVTF
CCCHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
HVKGTGLHCLSIERDLMKKFHLKDAFIIPTPLNNYHDSLGKAAAQYLETQLQQGDLLGIG
EEECCCEEEEHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEC
WGETISKMLENIHFESSINLSIVTLTGGVNHYLPRKQNYLHYMQGDLHIIPTPFLASTTE
CHHHHHHHHHHCCCCCCCCEEEEEEECCCHHCCCCCCCHHHHCCCCEEEECCCHHHHHHH
MAQSILSEPSVKDMLHVASLAHTAVVGIGGLSQDATIVKEEKLTLREMTYIRSQNGAGDI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCHH
LGQFYDTNGGLLELSHHNRLIGTPLPVLRNMKHVVGVAGGTEKIDAIYGALKGKFIHTLI
HHHEECCCCCEEEECCCCCCCCCCHHHHHCHHHHHCCCCCHHHHHHHHHHHCCCEEEEEE
TDEETALSLLRKDGDC
CCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]