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The map label for this gene is ectB [H]

Identifier: 227813907

GI number: 227813907

Start: 1189853

End: 1191127

Strand: Direct

Name: ectB [H]

Synonym: BAMEG_1313

Alternate gene names: 227813907

Gene position: 1189853-1191127 (Clockwise)

Preceding gene: 227813906

Following gene: 227813908

Centisome position: 22.75

GC content: 33.65

Gene sequence:

>1275_bases
ATGGTAGTTAGTTCAAAAATGGATATATTTAATGAACTAGAATCCCAAGTTCGAAGTTATAGCAGAAGCTTTCCAACGAT
CTTCACTAAGTCTAAAGGATATAAATTATGGGATGTAGATGGAAAAGAGTATATTGACTTTTTCTCAGGTGCTGGTGCTC
TTAATTATGGACATAATGATGATAAAATGAAGCAGGTATTAATAGATTATCTTTTAGAAGATGGTATTATTCATAGTCTT
GATATGGGAACAAGCGCTAAAGTGAATTTTTTAAAGCACTTTAACAAAATTATTTTGGAACCACGTGATTTAAATTATAA
AATTATGTTTCCTGGTCCAACAGGTACAAATTCTGTTGAAAGTGCACTGAAAATTGCTCGAAAAGTGACCGGGCGCACAA
ATATTATAAGTTTTTCTAATGCTTTTCATGGAATGAGTTTAGGATCACTTTCGATAACGAGTAATCATTTTAAGCGAAAG
GGTGCTGGAGTACCACTAAATAATAGTATTATCATGCCGTATGAAAATTATTTAGATTCTCTTAATTCTTTATCATATTT
AGAAAAAGTATTGGGCGATAGTGGAAGTGGAGTGGCTTTACCTGCTGCAATTATTCTAGAAACAGTTCAAGGTGAGGGTG
GTTTAAATACCGCTAGCTCCCAATGGTTAAAGGGAATTGACAGACTGTGTAAAAAATATAATATATTATTGATTGTCGAT
GATATTCAAGCAGGGTGCGGACGTACGGGGACATTTTTTAGCTTTGAACCTGCGAGCATTAAACCAGACATAATTTGTTT
GTCAAAATCTATAAGTGGCATTGGCCTTCCGATGGCTATTACACTAATTAAACCGGAATATGATAAGTGGGAACCAGGAG
AACATAATGGAACGTTTCGAGGGAATAATCTAGCATTTTTAGCAGCTACAGAAGCATTGAGTTATTGGAAAGATATAGAG
TTTATTAATGCTTTAAAATGGAAAAGTGAAAAAATCACTAGTTTTCTTAATGAGATTTGTTTGAAATACCCCCAACTTCA
AGGAGAAGTACGAGGGAGAGGCTTTATGCAGGGCATAGCGTGTAATACTTTTGGAATAGCTAAAAAGATTTGCTCAGTTG
CATTTGAAAATGGTCTAATTATTGAAACATCTGGACCTAATGATGAAGTTATTAAGTTGTTACCTTCTTTAACAATAGAC
TTAGAAGGATTAAGTAAAGGATTGGAAATGTTAGAGGATAGTATTTCTACTATTTTAAAAGAGGTAACTCACTAA

Upstream 100 bases:

>100_bases
TAAAGATATGCATTCGGTATAAATTTACAATAGCAATTATATAACTTTTCATTATTCTTTGTGAGTATAGTAAAAACGAA
AAATTAGGAGGTGCTCTTTT

Downstream 100 bases:

>100_bases
GTTTGAACGACTTGCACTTAATAACCTTGCGGACCGTTTGCAGTAGTTGCGGTAGAAGAAGGAAAAGAAGCGGCCCACAA
AGTGGATCTAACATTCTTAT

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MVVSSKMDIFNELESQVRSYSRSFPTIFTKSKGYKLWDVDGKEYIDFFSGAGALNYGHNDDKMKQVLIDYLLEDGIIHSL
DMGTSAKVNFLKHFNKIILEPRDLNYKIMFPGPTGTNSVESALKIARKVTGRTNIISFSNAFHGMSLGSLSITSNHFKRK
GAGVPLNNSIIMPYENYLDSLNSLSYLEKVLGDSGSGVALPAAIILETVQGEGGLNTASSQWLKGIDRLCKKYNILLIVD
DIQAGCGRTGTFFSFEPASIKPDIICLSKSISGIGLPMAITLIKPEYDKWEPGEHNGTFRGNNLAFLAATEALSYWKDIE
FINALKWKSEKITSFLNEICLKYPQLQGEVRGRGFMQGIACNTFGIAKKICSVAFENGLIIETSGPNDEVIKLLPSLTID
LEGLSKGLEMLEDSISTILKEVTH

Sequences:

>Translated_424_residues
MVVSSKMDIFNELESQVRSYSRSFPTIFTKSKGYKLWDVDGKEYIDFFSGAGALNYGHNDDKMKQVLIDYLLEDGIIHSL
DMGTSAKVNFLKHFNKIILEPRDLNYKIMFPGPTGTNSVESALKIARKVTGRTNIISFSNAFHGMSLGSLSITSNHFKRK
GAGVPLNNSIIMPYENYLDSLNSLSYLEKVLGDSGSGVALPAAIILETVQGEGGLNTASSQWLKGIDRLCKKYNILLIVD
DIQAGCGRTGTFFSFEPASIKPDIICLSKSISGIGLPMAITLIKPEYDKWEPGEHNGTFRGNNLAFLAATEALSYWKDIE
FINALKWKSEKITSFLNEICLKYPQLQGEVRGRGFMQGIACNTFGIAKKICSVAFENGLIIETSGPNDEVIKLLPSLTID
LEGLSKGLEMLEDSISTILKEVTH
>Mature_424_residues
MVVSSKMDIFNELESQVRSYSRSFPTIFTKSKGYKLWDVDGKEYIDFFSGAGALNYGHNDDKMKQVLIDYLLEDGIIHSL
DMGTSAKVNFLKHFNKIILEPRDLNYKIMFPGPTGTNSVESALKIARKVTGRTNIISFSNAFHGMSLGSLSITSNHFKRK
GAGVPLNNSIIMPYENYLDSLNSLSYLEKVLGDSGSGVALPAAIILETVQGEGGLNTASSQWLKGIDRLCKKYNILLIVD
DIQAGCGRTGTFFSFEPASIKPDIICLSKSISGIGLPMAITLIKPEYDKWEPGEHNGTFRGNNLAFLAATEALSYWKDIE
FINALKWKSEKITSFLNEICLKYPQLQGEVRGRGFMQGIACNTFGIAKKICSVAFENGLIIETSGPNDEVIKLLPSLTID
LEGLSKGLEMLEDSISTILKEVTH

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=422, Percent_Identity=28.436018957346, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI284507298, Length=314, Percent_Identity=28.343949044586, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI13994255, Length=388, Percent_Identity=25, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI188536080, Length=412, Percent_Identity=22.3300970873786, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38679950, Length=412, Percent_Identity=22.3300970873786, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38679946, Length=412, Percent_Identity=22.3300970873786, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI24119277, Length=440, Percent_Identity=22.2727272727273, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI37574042, Length=434, Percent_Identity=22.5806451612903, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=22.737819025522, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI226442709, Length=336, Percent_Identity=24.4047619047619, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789016, Length=422, Percent_Identity=29.8578199052133, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789759, Length=404, Percent_Identity=27.4752475247525, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI145693181, Length=375, Percent_Identity=30.1333333333333, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=29.8994974874372, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787560, Length=393, Percent_Identity=30.7888040712468, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1786991, Length=305, Percent_Identity=28.1967213114754, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786349, Length=316, Percent_Identity=26.2658227848101, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25144271, Length=413, Percent_Identity=28.0871670702179, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=291, Percent_Identity=28.5223367697594, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32564660, Length=428, Percent_Identity=25.9345794392523, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=446, Percent_Identity=21.9730941704036, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71992977, Length=339, Percent_Identity=21.2389380530973, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324432, Length=423, Percent_Identity=28.8416075650118, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6323470, Length=435, Percent_Identity=29.1954022988506, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6321456, Length=430, Percent_Identity=22.093023255814, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21357415, Length=407, Percent_Identity=28.009828009828, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=25.0569476082005, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28574759, Length=445, Percent_Identity=24.7191011235955, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281366494, Length=431, Percent_Identity=22.0417633410673, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24667139, Length=431, Percent_Identity=22.0417633410673, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24667143, Length=431, Percent_Identity=22.0417633410673, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46749; Mature: 46749

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVSSKMDIFNELESQVRSYSRSFPTIFTKSKGYKLWDVDGKEYIDFFSGAGALNYGHND
CCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCHHHHHHHCCCCCCCCCCCH
DKMKQVLIDYLLEDGIIHSLDMGTSAKVNFLKHFNKIILEPRDLNYKIMFPGPTGTNSVE
HHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
SALKIARKVTGRTNIISFSNAFHGMSLGSLSITSNHFKRKGAGVPLNNSIIMPYENYLDS
HHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECHHHHHHCCCCCCCCCCEECCHHHHHHH
LNSLSYLEKVLGDSGSGVALPAAIILETVQGEGGLNTASSQWLKGIDRLCKKYNILLIVD
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEE
DIQAGCGRTGTFFSFEPASIKPDIICLSKSISGIGLPMAITLIKPEYDKWEPGEHNGTFR
CCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
GNNLAFLAATEALSYWKDIEFINALKWKSEKITSFLNEICLKYPQLQGEVRGRGFMQGIA
CCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHC
CNTFGIAKKICSVAFENGLIIETSGPNDEVIKLLPSLTIDLEGLSKGLEMLEDSISTILK
CCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHH
EVTH
HHCC
>Mature Secondary Structure
MVVSSKMDIFNELESQVRSYSRSFPTIFTKSKGYKLWDVDGKEYIDFFSGAGALNYGHND
CCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCHHHHHHHCCCCCCCCCCCH
DKMKQVLIDYLLEDGIIHSLDMGTSAKVNFLKHFNKIILEPRDLNYKIMFPGPTGTNSVE
HHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
SALKIARKVTGRTNIISFSNAFHGMSLGSLSITSNHFKRKGAGVPLNNSIIMPYENYLDS
HHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECHHHHHHCCCCCCCCCCEECCHHHHHHH
LNSLSYLEKVLGDSGSGVALPAAIILETVQGEGGLNTASSQWLKGIDRLCKKYNILLIVD
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEE
DIQAGCGRTGTFFSFEPASIKPDIICLSKSISGIGLPMAITLIKPEYDKWEPGEHNGTFR
CCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
GNNLAFLAATEALSYWKDIEFINALKWKSEKITSFLNEICLKYPQLQGEVRGRGFMQGIA
CCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHC
CNTFGIAKKICSVAFENGLIIETSGPNDEVIKLLPSLTIDLEGLSKGLEMLEDSISTILK
CCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHH
EVTH
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]