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The map label for this gene is murG [H]

Identifier: 227082524

GI number: 227082524

Start: 2506983

End: 2508047

Strand: Reverse

Name: murG [H]

Synonym: VCM66_2324

Alternate gene names: 227082524

Gene position: 2508047-2506983 (Counterclockwise)

Preceding gene: 227082525

Following gene: 227082523

Centisome position: 86.71

GC content: 52.86

Gene sequence:

>1065_bases
TTGATGAACAAGAATAAAAAATTAATGGTGATGGCCGGAGGAACCGGCGGTCACGTATTTCCCGGTTTGGCTGTCGCCAA
ACAACTACAGCAACAGGGTTGGCAAATTCGTTGGTTGGGAACGGCTGACCGAATGGAAGCGGAATTGGTTCCTAAGCACG
GCATTGAGATTGACTTTATTCAAGTCAAAGGGCTGCGCGGCCAAGGGCTGATGCGCTTACTCAAAGCACCTTTCCAAATT
GTGAACGCGATTTTGCAAGCGCGCCGCCATTTGCTGACTTATCAGCCAGATGCAGTACTCGGCATGGGCGGTTATGTGAG
CGGACCCGGCGGGATTGCCGCTTGGTTACTGGGGATTCCAGTGGTGTTGCATGAGCAAAATGCGGTTGCTGGGCTGACTA
ACCAATGGCTGGCTAAAATTGCACGGCGTGTATTTCAAGCCTTCCCCGGAGCATTTGCTGACGCGTCTGTGGTGGGTAAC
CCAGTACGTCAAGATGTGGTACAACTTGCCGCGCCAGAGCAGCGTTTTGCCACGCGTAACGGCGCCATTCGAATTTTAGT
CATGGGTGGCAGCCAAGGTGCCCGCATCCTAAACCAAACCTTGCCAGCGGTGATGGCGGCATTAGGTGAGGGTTATGAAA
TCCGTCATCAAGCCGGTAAAAACAGCCAACAAGACGTGGCTGAGGCTTATGCTGCTGCCGGAGTGGAAAGCGCGCAAGTC
ACCGAATTTATTGATGATGTGGCAGATGCATACGCTTGGGCGGATCTGCTTATCTGTCGCTCAGGCGCATTGACCGTCTC
AGAGGTCTCAGCGGCGGGCGTTGGGGCGATTTTTATCCCTTTCATGCATAAAGATCGCCAGCAAGCACTCAACGCTGATC
ATTTAGTGGCTTGTGGAGCCGCCAAAATGATTGAGCAGCCCGAATTGAGTGTGGAAAAGCTGACCCAGATGGTGCGCGAA
CTCGATAGAGCACAATTATTGTCCATGGCTCAGAAGGCGCGCCAAGCCGCCAAATTAGATGCTGACAAGGTGGTGGCGCA
AGCGATCATCGCCATTACCGAATAA

Upstream 100 bases:

>100_bases
GGTTCCAGTTTAATTATTATGTCAGTGGCGGTGTCGATTTTACTGCGCATCGATCATGAATGCCGTTTAGCGGATCGCCA
CGCACCAGAAGAAATCACAG

Downstream 100 bases:

>100_bases
CGAGAACAGAATTATGACGATTAAACATACCCAAGACCTCGCCCAAATTCGCGCTATGGTGCCAGAGATGCGCCGTGTAA
AAGCGATCCACTTTATTGGC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MMNKNKKLMVMAGGTGGHVFPGLAVAKQLQQQGWQIRWLGTADRMEAELVPKHGIEIDFIQVKGLRGQGLMRLLKAPFQI
VNAILQARRHLLTYQPDAVLGMGGYVSGPGGIAAWLLGIPVVLHEQNAVAGLTNQWLAKIARRVFQAFPGAFADASVVGN
PVRQDVVQLAAPEQRFATRNGAIRILVMGGSQGARILNQTLPAVMAALGEGYEIRHQAGKNSQQDVAEAYAAAGVESAQV
TEFIDDVADAYAWADLLICRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVACGAAKMIEQPELSVEKLTQMVRE
LDRAQLLSMAQKARQAAKLDADKVVAQAIIAITE

Sequences:

>Translated_354_residues
MMNKNKKLMVMAGGTGGHVFPGLAVAKQLQQQGWQIRWLGTADRMEAELVPKHGIEIDFIQVKGLRGQGLMRLLKAPFQI
VNAILQARRHLLTYQPDAVLGMGGYVSGPGGIAAWLLGIPVVLHEQNAVAGLTNQWLAKIARRVFQAFPGAFADASVVGN
PVRQDVVQLAAPEQRFATRNGAIRILVMGGSQGARILNQTLPAVMAALGEGYEIRHQAGKNSQQDVAEAYAAAGVESAQV
TEFIDDVADAYAWADLLICRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVACGAAKMIEQPELSVEKLTQMVRE
LDRAQLLSMAQKARQAAKLDADKVVAQAIIAITE
>Mature_354_residues
MMNKNKKLMVMAGGTGGHVFPGLAVAKQLQQQGWQIRWLGTADRMEAELVPKHGIEIDFIQVKGLRGQGLMRLLKAPFQI
VNAILQARRHLLTYQPDAVLGMGGYVSGPGGIAAWLLGIPVVLHEQNAVAGLTNQWLAKIARRVFQAFPGAFADASVVGN
PVRQDVVQLAAPEQRFATRNGAIRILVMGGSQGARILNQTLPAVMAALGEGYEIRHQAGKNSQQDVAEAYAAAGVESAQV
TEFIDDVADAYAWADLLICRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVACGAAKMIEQPELSVEKLTQMVRE
LDRAQLLSMAQKARQAAKLDADKVVAQAIIAITE

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=349, Percent_Identity=64.756446991404, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 37984; Mature: 37984

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNKNKKLMVMAGGTGGHVFPGLAVAKQLQQQGWQIRWLGTADRMEAELVPKHGIEIDFI
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCEEEEE
QVKGLRGQGLMRLLKAPFQIVNAILQARRHLLTYQPDAVLGMGGYVSGPGGIAAWLLGIP
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHCC
VVLHEQNAVAGLTNQWLAKIARRVFQAFPGAFADASVVGNPVRQDVVQLAAPEQRFATRN
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHCCHHHHHCCC
GAIRILVMGGSQGARILNQTLPAVMAALGEGYEIRHQAGKNSQQDVAEAYAAAGVESAQV
CCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHHHHCCCCHHHH
TEFIDDVADAYAWADLLICRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVACGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEHHHHHCCHHHHCCCCCEEHHCH
AKMIEQPELSVEKLTQMVRELDRAQLLSMAQKARQAAKLDADKVVAQAIIAITE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MMNKNKKLMVMAGGTGGHVFPGLAVAKQLQQQGWQIRWLGTADRMEAELVPKHGIEIDFI
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCEEEEE
QVKGLRGQGLMRLLKAPFQIVNAILQARRHLLTYQPDAVLGMGGYVSGPGGIAAWLLGIP
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHCC
VVLHEQNAVAGLTNQWLAKIARRVFQAFPGAFADASVVGNPVRQDVVQLAAPEQRFATRN
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHCCHHHHHCCC
GAIRILVMGGSQGARILNQTLPAVMAALGEGYEIRHQAGKNSQQDVAEAYAAAGVESAQV
CCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHHHHCCCCHHHH
TEFIDDVADAYAWADLLICRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVACGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEHHHHHCCHHHHCCCCCEEHHCH
AKMIEQPELSVEKLTQMVRELDRAQLLSMAQKARQAAKLDADKVVAQAIIAITE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA