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The map label for this gene is asd [H]

Identifier: 227082232

GI number: 227082232

Start: 2200829

End: 2201845

Strand: Reverse

Name: asd [H]

Synonym: VCM66_2030

Alternate gene names: 227082232

Gene position: 2201845-2200829 (Counterclockwise)

Preceding gene: 227082233

Following gene: 227082230

Centisome position: 76.12

GC content: 49.36

Gene sequence:

>1017_bases
GTGATGAGCCAACAATTTAATGTTGCCATTTTTGGCGCAACCGGCGCTGTAGGCGAAACCATGTTGGAAGTACTGCAGGA
GCGTGAGTTTCCTGTGGATGAACTTTTCCTGCTGGCCAGTGAGCGCAGTGAGGGAAAAACCTATCGCTTCAACGGTAAAA
CCGTGCGTGTGCAAAATGTCGAAGAATTTGACTGGTCGCAAGTGCATATTGCGCTGTTTTCTGCCGGTGGTGAGCTTTCT
GCCAAGTGGGCTCCGATTGCCGCAGAAGCGGGTGTTGTGGTGATCGACAACACTTCACACTTCCGTTACGACTACGACAT
TCCTCTTGTGGTACCTGAAGTGAACCCAGAGGCGATTGCCGAATTTCGTAACCGCAATATTATTGCTAACCCAAACTGCT
CAACCATTCAGATGCTTGTCGCGCTAAAGCCGATTTACGATGCGGTGGGGATTGAACGCATTAACGTGACGACTTACCAA
TCGGTCTCAGGTGCTGGGAAAGCTGGGATTGATGAGTTAGCAGGACAAACCGCTAAACTGCTCAATGGCTATCCAGCGGA
AACGAATACTTTTAGCCAGCAGATCGCGTTTAACTGTATTCCACAAATCGATCAGTTTATGGACAACGGTTATACCAAAG
AAGAGATGAAGATGGTGTGGGAAACCCAGAAAATCTTCAATGATCCTTCGATCATGGTCAACCCAACGTGCGTACGTGTA
CCGGTATTCTACGGTCATGCGGAAGCCGTACACGTGGAAACTCGCGCGCCAATTGATGCTGAGCAAGTGATGGATATGCT
AGAGCAAACCGATGGTATTGAACTGTTCCGCGGTGCGGATTTCCCAACTCAAGTGCGTGATGCCGGCGGTAAAGACCATG
TGTTGGTTGGGCGTGTACGAAATGACATTAGCCACCATAGTGGAATCAACTTGTGGGTAGTGGCGGATAACGTGCGTAAA
GGTGCTGCCACCAATGCGGTGCAAATTGCAGAGCTGCTCGTACGCGATTACTTCTAA

Upstream 100 bases:

>100_bases
CACTATTGGGATAGACGTGAATACAGCGCGGTGACTCTAGCTGGAGGCGCTGATTGCCATTTGGCTCCTTTGGCTAAACT
CGGTTTTCAAGTAGAGGTAT

Downstream 100 bases:

>100_bases
GCTTTTCATCAAGTTATAAAAAACCCACCATTCGGTGGGTTTTTACTATCTGGTTCGGTTTACAGAGCGTAAAGCCTATG
GTTATTTCTTCGGCTTGTGA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MMSQQFNVAIFGATGAVGETMLEVLQEREFPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWSQVHIALFSAGGELS
AKWAPIAAEAGVVVIDNTSHFRYDYDIPLVVPEVNPEAIAEFRNRNIIANPNCSTIQMLVALKPIYDAVGIERINVTTYQ
SVSGAGKAGIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKIFNDPSIMVNPTCVRV
PVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIELFRGADFPTQVRDAGGKDHVLVGRVRNDISHHSGINLWVVADNVRK
GAATNAVQIAELLVRDYF

Sequences:

>Translated_338_residues
MMSQQFNVAIFGATGAVGETMLEVLQEREFPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWSQVHIALFSAGGELS
AKWAPIAAEAGVVVIDNTSHFRYDYDIPLVVPEVNPEAIAEFRNRNIIANPNCSTIQMLVALKPIYDAVGIERINVTTYQ
SVSGAGKAGIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKIFNDPSIMVNPTCVRV
PVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIELFRGADFPTQVRDAGGKDHVLVGRVRNDISHHSGINLWVVADNVRK
GAATNAVQIAELLVRDYF
>Mature_338_residues
MMSQQFNVAIFGATGAVGETMLEVLQEREFPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWSQVHIALFSAGGELS
AKWAPIAAEAGVVVIDNTSHFRYDYDIPLVVPEVNPEAIAEFRNRNIIANPNCSTIQMLVALKPIYDAVGIERINVTTYQ
SVSGAGKAGIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKIFNDPSIMVNPTCVRV
PVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIELFRGADFPTQVRDAGGKDHVLVGRVRNDISHHSGINLWVVADNVRK
GAATNAVQIAELLVRDYF

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=338, Percent_Identity=47.6331360946746, Blast_Score=317, Evalue=6e-88,
Organism=Escherichia coli, GI1789841, Length=293, Percent_Identity=25.2559726962457, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320362, Length=408, Percent_Identity=28.1862745098039, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37507; Mature: 37507

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSQQFNVAIFGATGAVGETMLEVLQEREFPVDELFLLASERSEGKTYRFNGKTVRVQNV
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEEECCCEEEECCC
EEFDWSQVHIALFSAGGELSAKWAPIAAEAGVVVIDNTSHFRYDYDIPLVVPEVNPEAIA
CCCCCCEEEEEEEECCCCCCCCCCCEECCCCEEEEECCCCEEEECCCEEEEECCCHHHHH
EFRNRNIIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKAGIDELAGQTAKL
HHHCCCEEECCCCHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCCCHHHHHCHHHHH
LNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKIFNDPSIMVNPTCVRV
HCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCEEEEE
PVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIELFRGADFPTQVRDAGGKDHVLVGRVR
EEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHCCCCCCCEEEEHHH
NDISHHSGINLWVVADNVRKGAATNAVQIAELLVRDYF
HHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MMSQQFNVAIFGATGAVGETMLEVLQEREFPVDELFLLASERSEGKTYRFNGKTVRVQNV
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEEECCCEEEECCC
EEFDWSQVHIALFSAGGELSAKWAPIAAEAGVVVIDNTSHFRYDYDIPLVVPEVNPEAIA
CCCCCCEEEEEEEECCCCCCCCCCCEECCCCEEEEECCCCEEEECCCEEEEECCCHHHHH
EFRNRNIIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKAGIDELAGQTAKL
HHHCCCEEECCCCHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCCCHHHHHCHHHHH
LNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKIFNDPSIMVNPTCVRV
HCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCEEEEE
PVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIELFRGADFPTQVRDAGGKDHVLVGRVR
EEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHCCCCCCCEEEEHHH
NDISHHSGINLWVVADNVRKGAATNAVQIAELLVRDYF
HHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]