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The map label for this gene is ccmB [H]

Identifier: 227082183

GI number: 227082183

Start: 2149016

End: 2149684

Strand: Reverse

Name: ccmB [H]

Synonym: VCM66_1980

Alternate gene names: 227082183

Gene position: 2149684-2149016 (Counterclockwise)

Preceding gene: 227082184

Following gene: 227082182

Centisome position: 74.32

GC content: 49.48

Gene sequence:

>669_bases
ATGATGCCTGCTTTTATTCAGTTTATTCATCGTGAACTTTTAATTGCTTTTCGCCGTCAGGCGGATGTGTTTAACCCTCT
GTGGTTTTTTATCATCGTGATTACCCTGTTTCCGCTCAGTGTGGGACCAGAACCTGCCTTGTTGGCACGAATTGCGCCGG
GGATTGTTTGGGTGGCCGCTTTATTAGCGGCATTGCTCTCATTGGAGCGTTTATTTCGTGATGATTTTCAAGATGGTGCA
TTAGAGCAAGCGATGCTGACACCATTACCGCTCTCAGTGGTGGTACTGGCTAAGGTGACGGCTCATTGGCTACTGACAGG
CTTACCGCTGATTTTAATTAGCCCACTACTGGCGATCTTGCTTTCATTTGATAGCTCAGCCTGGCTTGCGGTAGTGCTGA
CTCTGTTGCTGGGGACTCCAACACTGAGTTTTATTGGGGCAATTGGGGTGGCACTCACCGTGGGTTTGCAAAAGGGTGGG
GTGCTATTGAGCTTATTGGTTTTGCCGCTCTTCATCCCTGTTTTGATATTTGCGACCTCGGCGATTGATGCGGCGGCATT
GGGAATGCCGTATAACGGCCAGCTTGCGATTTTAGCGGCTATGCTCATGGGTTCGATGACTCTAACGCCATTTGCGATCA
GCGCGGCGTTACGAGTAAGTGTGCATTGA

Upstream 100 bases:

>100_bases
TAAGCCATGCGCAGCAAGGGGGGATAGTGATACTGACGACTCACCAAGACATGTTTGCCGATAACCCTAAACTGCGCAAA
ATTCGCTTGGGTGATCCGAA

Downstream 100 bases:

>100_bases
TTGTTTTCGATCAAGCACGAAAATACTGCGTTAGATAAATTATAACAACTTAGTTAAAACTCAATAATTTGAAAGCAAAG
TGAGATAAACATGTGGAAAT

Product: heme exporter protein B

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MMPAFIQFIHRELLIAFRRQADVFNPLWFFIIVITLFPLSVGPEPALLARIAPGIVWVAALLAALLSLERLFRDDFQDGA
LEQAMLTPLPLSVVVLAKVTAHWLLTGLPLILISPLLAILLSFDSSAWLAVVLTLLLGTPTLSFIGAIGVALTVGLQKGG
VLLSLLVLPLFIPVLIFATSAIDAAALGMPYNGQLAILAAMLMGSMTLTPFAISAALRVSVH

Sequences:

>Translated_222_residues
MMPAFIQFIHRELLIAFRRQADVFNPLWFFIIVITLFPLSVGPEPALLARIAPGIVWVAALLAALLSLERLFRDDFQDGA
LEQAMLTPLPLSVVVLAKVTAHWLLTGLPLILISPLLAILLSFDSSAWLAVVLTLLLGTPTLSFIGAIGVALTVGLQKGG
VLLSLLVLPLFIPVLIFATSAIDAAALGMPYNGQLAILAAMLMGSMTLTPFAISAALRVSVH
>Mature_222_residues
MMPAFIQFIHRELLIAFRRQADVFNPLWFFIIVITLFPLSVGPEPALLARIAPGIVWVAALLAALLSLERLFRDDFQDGA
LEQAMLTPLPLSVVVLAKVTAHWLLTGLPLILISPLLAILLSFDSSAWLAVVLTLLLGTPTLSFIGAIGVALTVGLQKGG
VLLSLLVLPLFIPVLIFATSAIDAAALGMPYNGQLAILAAMLMGSMTLTPFAISAALRVSVH

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=218, Percent_Identity=67.4311926605505, Blast_Score=235, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23698; Mature: 23698

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPAFIQFIHRELLIAFRRQADVFNPLWFFIIVITLFPLSVGPEPALLARIAPGIVWVAA
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLAALLSLERLFRDDFQDGALEQAMLTPLPLSVVVLAKVTAHWLLTGLPLILISPLLAIL
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFDSSAWLAVVLTLLLGTPTLSFIGAIGVALTVGLQKGGVLLSLLVLPLFIPVLIFATS
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIDAAALGMPYNGQLAILAAMLMGSMTLTPFAISAALRVSVH
HHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMPAFIQFIHRELLIAFRRQADVFNPLWFFIIVITLFPLSVGPEPALLARIAPGIVWVAA
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLAALLSLERLFRDDFQDGALEQAMLTPLPLSVVVLAKVTAHWLLTGLPLILISPLLAIL
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFDSSAWLAVVLTLLLGTPTLSFIGAIGVALTVGLQKGGVLLSLLVLPLFIPVLIFATS
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIDAAALGMPYNGQLAILAAMLMGSMTLTPFAISAALRVSVH
HHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]