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The map label for this gene is fadH [H]

Identifier: 227082120

GI number: 227082120

Start: 2081857

End: 2083857

Strand: Reverse

Name: fadH [H]

Synonym: VCM66_1917

Alternate gene names: 227082120

Gene position: 2083857-2081857 (Counterclockwise)

Preceding gene: 227082123

Following gene: 227082117

Centisome position: 72.04

GC content: 51.77

Gene sequence:

>2001_bases
ATGTACCCAAATCTATTTCAGCCTCTCGATCTTGGTTTTACTCAGCTCAAAAATCGTGTGTTGATGGGCTCTATGCATAC
TGGCTTAGAAGAAAATAAGGAAGGGCTGCACAAGCTGGCGGCCTTTTATGAAGAACGTGCCAAAGGTGGCGTAGGCTTGA
TTGTGACGGGTGGCTTTTCGCCTAACTTGCGCGGCCGTCTGCACCCATTCAGCGCTGAATTTAGCAAAACTAAGCATGCC
AAAGCCCATAAAGTGGTGACAGAAGCGGTGCACCGTCATGGCGCTAAAATCGCTTTGCAACTGCTGCATGCGGGGCGTTA
TGCGATGCATCCATTTTCACAAAGTGCTTCCGCGATTCGTGCACCGATTGCCAAGTTTGCCCCGAGTGAAATGAGCACTC
GCCAAATCCGCAATACCATCCAAGACTTCGCCAATAGCGCCGAGCTTGCACAACTGGCGGGCTATGATGGCGTCGAAGTG
ATGGGGTCAGAAGGTTATTTGATTAACCAGTTCATCTGTAAGCGCACCAACATGCGTTACGACGAGTGGGGCGGCAGTTA
TCAAAACCGCATTCGTTTTCCAGTTGAAATTGTTAAAGCTATCCGTGAAGCGGTTGGCAAAGAGTTCATCATTATCTTTC
GTCTGTCGATGCTCGATTTGGTGGAGCAGGGCAGCACTTTTGAAGAGGTGGTGGTGCTTGCCAAAGCCTTAGAAGAGGCG
GGGGTCACCATTATCAATACCGGGATCGGCTGGCATGAAGCGCGTATTCCCACAATAGCGACCCAAGTGCCGCGTGCCGC
CTTTAGCTGGGTGACGGAGAAGATCAAACCCTATTTAAAAGTGCCTGTCGTGACCTGTAACCGCATTAACACGCCGGAGC
AAGCGGAGAAAATTTTGGCGAGTGGTCAGGCGGATATGGTGTCGATGGCGCGCCCGTTTTTAGCCGATGCGGATTTTGTA
CGCAAAGCGCAAGAAGGGCAGAGCGCGCTCATCAATACCTGTATTGGTTGTAATCAAGCTTGTTTGGACAACGTCTTTCG
TGGCAAACGTGCCAGCTGCTTGGTGAACCCGCGCGCTTGTTATGAAACTGAGATTGTGGTTAAACCCGCACAGAGCAAAA
AAATTGCGGTTGTCGGTGCTGGCCCTGCCGGTTTAGCGTTTGCGACGACCGCTTCAGAGCGTGGTCATCAAGTGGATCTG
TTTGAACGCAATGACAGAATCGGTGGCCAATTCCGTCTTGCGATGCAGATCCCCGGCAAAGAAGAGTTTCGGGAAACCAT
TCGCTATTTTGCTAACCGGATTGATCAAACTGGCGTGAAGTTGCACCTGGGTTGTGAAGTGCAATTTAGCGATCTGCGTG
GCTACGATGAAGTGGTGATCGCCACGGGCGTGACACCTCGCAAAATCGCCCTAGCGGGGCTGAGTGAATCATCAAAAGTA
GTTGATTACCAAACCTTAATTCGCGAAAAGACACCCGTAGGCCAAAAGGTCGCGATTGTCGGCGCTGGCGGTATTGGGGT
GGATGTGGCGAGCATGCTCACCGAGCCGAAAGATCAAACTTTAGATGATTGGTTATACGAATGGGGGATTGATAAAGCCA
TCGAGCACCCCGGCGGTTTGTACCCATATCCTGAGACAACCAGTGAGCGTGAAGTCTGGCTGCTGCAAAGGCGCAAAGGC
GCGGTGGGTAAAGGGCCGGGTAAAACCACGGGCTGGATCCATAAACGCACGTTAGAAAAACGCGGTGTGCATTTGGTTGG
TGGCGTGCAGTATCAGAAAATCGATGAGCAAGGTCTGCATATTGAGCGTGATGGAAAATCAGAGCTGATTGATGCTGATA
GTGTGGTGATTTGTGCAGGTCAAGAATCCGTGCGTCCTTTTGAGGCGCAGTGGGCTGAGCTGGGCGATAAGCTGCATGTG
ATTGGTGGGGCGGATGTCGCCGGAGAGCTGGATGCTGCGCGCGCGATTCGTCAAGGTGTGGAGCTGGCAGTTCGATTGTA
A

Upstream 100 bases:

>100_bases
CTTGATCGCTGTTACACAAATGTAAACACTTGTTTGATTTTTGTAATTGGCAAGAATATTCTGGTCAGACCATATCAATA
AGAAGCAAAGTGAAGTCGCT

Downstream 100 bases:

>100_bases
CTTGTTGAGTGAAAACCATGAACGGCAAAGGGCACTTCGGTGCCCTTTGTTATTGTCTACTGCTGAGGGTTCGTTACAAA
ATGACGGTCTTGTTGCCGTA

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MYPNLFQPLDLGFTQLKNRVLMGSMHTGLEENKEGLHKLAAFYEERAKGGVGLIVTGGFSPNLRGRLHPFSAEFSKTKHA
KAHKVVTEAVHRHGAKIALQLLHAGRYAMHPFSQSASAIRAPIAKFAPSEMSTRQIRNTIQDFANSAELAQLAGYDGVEV
MGSEGYLINQFICKRTNMRYDEWGGSYQNRIRFPVEIVKAIREAVGKEFIIIFRLSMLDLVEQGSTFEEVVVLAKALEEA
GVTIINTGIGWHEARIPTIATQVPRAAFSWVTEKIKPYLKVPVVTCNRINTPEQAEKILASGQADMVSMARPFLADADFV
RKAQEGQSALINTCIGCNQACLDNVFRGKRASCLVNPRACYETEIVVKPAQSKKIAVVGAGPAGLAFATTASERGHQVDL
FERNDRIGGQFRLAMQIPGKEEFRETIRYFANRIDQTGVKLHLGCEVQFSDLRGYDEVVIATGVTPRKIALAGLSESSKV
VDYQTLIREKTPVGQKVAIVGAGGIGVDVASMLTEPKDQTLDDWLYEWGIDKAIEHPGGLYPYPETTSEREVWLLQRRKG
AVGKGPGKTTGWIHKRTLEKRGVHLVGGVQYQKIDEQGLHIERDGKSELIDADSVVICAGQESVRPFEAQWAELGDKLHV
IGGADVAGELDAARAIRQGVELAVRL

Sequences:

>Translated_666_residues
MYPNLFQPLDLGFTQLKNRVLMGSMHTGLEENKEGLHKLAAFYEERAKGGVGLIVTGGFSPNLRGRLHPFSAEFSKTKHA
KAHKVVTEAVHRHGAKIALQLLHAGRYAMHPFSQSASAIRAPIAKFAPSEMSTRQIRNTIQDFANSAELAQLAGYDGVEV
MGSEGYLINQFICKRTNMRYDEWGGSYQNRIRFPVEIVKAIREAVGKEFIIIFRLSMLDLVEQGSTFEEVVVLAKALEEA
GVTIINTGIGWHEARIPTIATQVPRAAFSWVTEKIKPYLKVPVVTCNRINTPEQAEKILASGQADMVSMARPFLADADFV
RKAQEGQSALINTCIGCNQACLDNVFRGKRASCLVNPRACYETEIVVKPAQSKKIAVVGAGPAGLAFATTASERGHQVDL
FERNDRIGGQFRLAMQIPGKEEFRETIRYFANRIDQTGVKLHLGCEVQFSDLRGYDEVVIATGVTPRKIALAGLSESSKV
VDYQTLIREKTPVGQKVAIVGAGGIGVDVASMLTEPKDQTLDDWLYEWGIDKAIEHPGGLYPYPETTSEREVWLLQRRKG
AVGKGPGKTTGWIHKRTLEKRGVHLVGGVQYQKIDEQGLHIERDGKSELIDADSVVICAGQESVRPFEAQWAELGDKLHV
IGGADVAGELDAARAIRQGVELAVRL
>Mature_666_residues
MYPNLFQPLDLGFTQLKNRVLMGSMHTGLEENKEGLHKLAAFYEERAKGGVGLIVTGGFSPNLRGRLHPFSAEFSKTKHA
KAHKVVTEAVHRHGAKIALQLLHAGRYAMHPFSQSASAIRAPIAKFAPSEMSTRQIRNTIQDFANSAELAQLAGYDGVEV
MGSEGYLINQFICKRTNMRYDEWGGSYQNRIRFPVEIVKAIREAVGKEFIIIFRLSMLDLVEQGSTFEEVVVLAKALEEA
GVTIINTGIGWHEARIPTIATQVPRAAFSWVTEKIKPYLKVPVVTCNRINTPEQAEKILASGQADMVSMARPFLADADFV
RKAQEGQSALINTCIGCNQACLDNVFRGKRASCLVNPRACYETEIVVKPAQSKKIAVVGAGPAGLAFATTASERGHQVDL
FERNDRIGGQFRLAMQIPGKEEFRETIRYFANRIDQTGVKLHLGCEVQFSDLRGYDEVVIATGVTPRKIALAGLSESSKV
VDYQTLIREKTPVGQKVAIVGAGGIGVDVASMLTEPKDQTLDDWLYEWGIDKAIEHPGGLYPYPETTSEREVWLLQRRKG
AVGKGPGKTTGWIHKRTLEKRGVHLVGGVQYQKIDEQGLHIERDGKSELIDADSVVICAGQESVRPFEAQWAELGDKLHV
IGGADVAGELDAARAIRQGVELAVRL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=671, Percent_Identity=56.6318926974665, Blast_Score=771, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=345, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559802, Length=255, Percent_Identity=30.5882352941176, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17566914, Length=314, Percent_Identity=28.343949044586, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=254, Percent_Identity=27.9527559055118, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564188, Length=253, Percent_Identity=27.6679841897233, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=300, Percent_Identity=27.3333333333333, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI72001454, Length=255, Percent_Identity=28.2352941176471, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540738, Length=309, Percent_Identity=25.5663430420712, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=238, Percent_Identity=29.8319327731092, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=255, Percent_Identity=26.2745098039216, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73241; Mature: 73241

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPNLFQPLDLGFTQLKNRVLMGSMHTGLEENKEGLHKLAAFYEERAKGGVGLIVTGGFS
CCCCCCCCHHCCHHHHHCHHEECHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
PNLRGRLHPFSAEFSKTKHAKAHKVVTEAVHRHGAKIALQLLHAGRYAMHPFSQSASAIR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHCCCCHHCHHHHH
APIAKFAPSEMSTRQIRNTIQDFANSAELAQLAGYDGVEVMGSEGYLINQFICKRTNMRY
HHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCH
DEWGGSYQNRIRFPVEIVKAIREAVGKEFIIIFRLSMLDLVEQGSTFEEVVVLAKALEEA
HHCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GVTIINTGIGWHEARIPTIATQVPRAAFSWVTEKIKPYLKVPVVTCNRINTPEQAEKILA
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECEEEECCCCCHHHHHHHHH
SGQADMVSMARPFLADADFVRKAQEGQSALINTCIGCNQACLDNVFRGKRASCLVNPRAC
CCCHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCHHH
YETEIVVKPAQSKKIAVVGAGPAGLAFATTASERGHQVDLFERNDRIGGQFRLAMQIPGK
CCEEEEEECCCCCEEEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEEECCCH
EEFRETIRYFANRIDQTGVKLHLGCEVQFSDLRGYDEVVIATGVTPRKIALAGLSESSKV
HHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCHHEEEECCCCCCCH
VDYQTLIREKTPVGQKVAIVGAGGIGVDVASMLTEPKDQTLDDWLYEWGIDKAIEHPGGL
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCHHHHCCCCCC
YPYPETTSEREVWLLQRRKGAVGKGPGKTTGWIHKRTLEKRGVHLVGGVQYQKIDEQGLH
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCEEEECCCCCCE
IERDGKSELIDADSVVICAGQESVRPFEAQWAELGDKLHVIGGADVAGELDAARAIRQGV
EECCCCCCEECCCCEEEECCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCH
ELAVRL
HEEECC
>Mature Secondary Structure
MYPNLFQPLDLGFTQLKNRVLMGSMHTGLEENKEGLHKLAAFYEERAKGGVGLIVTGGFS
CCCCCCCCHHCCHHHHHCHHEECHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
PNLRGRLHPFSAEFSKTKHAKAHKVVTEAVHRHGAKIALQLLHAGRYAMHPFSQSASAIR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHCCCCHHCHHHHH
APIAKFAPSEMSTRQIRNTIQDFANSAELAQLAGYDGVEVMGSEGYLINQFICKRTNMRY
HHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCH
DEWGGSYQNRIRFPVEIVKAIREAVGKEFIIIFRLSMLDLVEQGSTFEEVVVLAKALEEA
HHCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GVTIINTGIGWHEARIPTIATQVPRAAFSWVTEKIKPYLKVPVVTCNRINTPEQAEKILA
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECEEEECCCCCHHHHHHHHH
SGQADMVSMARPFLADADFVRKAQEGQSALINTCIGCNQACLDNVFRGKRASCLVNPRAC
CCCHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCHHH
YETEIVVKPAQSKKIAVVGAGPAGLAFATTASERGHQVDLFERNDRIGGQFRLAMQIPGK
CCEEEEEECCCCCEEEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEEECCCH
EEFRETIRYFANRIDQTGVKLHLGCEVQFSDLRGYDEVVIATGVTPRKIALAGLSESSKV
HHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCHHEEEECCCCCCCH
VDYQTLIREKTPVGQKVAIVGAGGIGVDVASMLTEPKDQTLDDWLYEWGIDKAIEHPGGL
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCHHHHCCCCCC
YPYPETTSEREVWLLQRRKGAVGKGPGKTTGWIHKRTLEKRGVHLVGGVQYQKIDEQGLH
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCEEEECCCCCCE
IERDGKSELIDADSVVICAGQESVRPFEAQWAELGDKLHVIGGADVAGELDAARAIRQGV
EECCCCCCEECCCCEEEECCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCH
ELAVRL
HEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]