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The map label for this gene is yfbQ [H]

Identifier: 227082104

GI number: 227082104

Start: 2066269

End: 2067483

Strand: Direct

Name: yfbQ [H]

Synonym: VCM66_1901

Alternate gene names: 227082104

Gene position: 2066269-2067483 (Clockwise)

Preceding gene: 227082097

Following gene: 227082105

Centisome position: 71.43

GC content: 49.88

Gene sequence:

>1215_bases
ATGCAAAATATCGGGATGTCGTCAAAACTCGATAATGTCTGCTATGACATTCGAGGACCAGTGCTTAAACATGCTAAACG
CATGGAAGAAGAAGGGCATAAAATACTGAAGCTTAACATCGGTAACCCTGCCCCGTTTGGTTTCGACGCCCCAGACGAGA
TCCTAGTCGATGTGATCCGTAACCTACCTACTTCACAAGGTTACTGTGACTCGAAAGGCATTTATTCCGCTCGTAAAGCG
GTGGTGCAGTACTACCAGAAAAAAGGTATCCGCAGTCTGGACGTCGAAGATGTGTACATCGGCAACGGTGCATCAGAGCT
TATCGTGATGGCGATGCAAGCCCTGCTCAACAATGGCGATGAAATGCTGGTACCTGCCCCTGATTACCCACTGTGGACAG
CCGCGGTAGCACTTTCTGGCGGCAAAGCCGTGCACTACATCTGTGATGAAGAAGCCGATTGGTATCCTGACCTCGACGAT
ATTCGCAGCAAAATCACCCCGAAAACCCGTGGCATTGTGCTGATCAACCCCAATAACCCAACCGGTGCGGTTTACAGTCG
TGATTTCTTGCTGGAAATCATCGAGATTGCTCGCAAGCACAAGCTGATGATTTTCGCCGATGAGATTTACGACAAAGTGC
TGTACGACGGCGCGGTGCATACCTCAATCGCCACCTTAGCGGATGATGTATTAGTCGTCACCTTCAACGGCTTATCCAAA
GCTTACCGTGTTTGTGGTTTCCGTGGTGGCTGGATGTTCCTGACTGGCCCCAAACAGCAAGCACAAGGCTATATTGCAGG
GCTCGATATGCTGGCCTCGATGCGCTTGTGTGCCAACGTGCCAATGCAACATGCCATTCAAACCGCACTCGGCGGCTATC
AAAGTATCAATGAGCTGATTTTGCCGGGCGGCCGACTGCTGGAACAGCGTGATCGCGCATGGGAGCTGATTAACCAGATC
CCGGGGATTTCTTGCGTGAAGCCAAAAGGCGCGATGTACCTGTTCCCGAAAATTGATACCAAAATGTATCCGATCAAAGA
TGACCAGAAAATGGTGCTTGATTTCCTAGTGCAAGAAAAAGTGCTGCTAGTACAAGGCAGCGGCTTTAACTGGCCAAAAC
CGGATCACTTCCGCATTGTGACTCTGCCTCATGTGGAAGATCTGGAAATCGCCATCAGTCGCTTTGAACGCTTTATCACG
ACTTACAGCCAATAA

Upstream 100 bases:

>100_bases
CTTCTGATTTTAAAACCAGGTTGTCTTAGATTTTTATTCTAAAAAATGGCAAGTTAGTGTAGTTTGATCAAGAAAACAGA
TTATTTTCAGGAATATTACA

Downstream 100 bases:

>100_bases
TAGATTGGCAGCAAGTCGCAAAATGACTTGCTGTCGTGGGTAGGCGAAGCAGGCTCTCTTTCGGTACACTGAAGAGAGCC
TGTTTTTTTATCTTCTTTTC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MQNIGMSSKLDNVCYDIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIRNLPTSQGYCDSKGIYSARKA
VVQYYQKKGIRSLDVEDVYIGNGASELIVMAMQALLNNGDEMLVPAPDYPLWTAAVALSGGKAVHYICDEEADWYPDLDD
IRSKITPKTRGIVLINPNNPTGAVYSRDFLLEIIEIARKHKLMIFADEIYDKVLYDGAVHTSIATLADDVLVVTFNGLSK
AYRVCGFRGGWMFLTGPKQQAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELILPGGRLLEQRDRAWELINQI
PGISCVKPKGAMYLFPKIDTKMYPIKDDQKMVLDFLVQEKVLLVQGSGFNWPKPDHFRIVTLPHVEDLEIAISRFERFIT
TYSQ

Sequences:

>Translated_404_residues
MQNIGMSSKLDNVCYDIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIRNLPTSQGYCDSKGIYSARKA
VVQYYQKKGIRSLDVEDVYIGNGASELIVMAMQALLNNGDEMLVPAPDYPLWTAAVALSGGKAVHYICDEEADWYPDLDD
IRSKITPKTRGIVLINPNNPTGAVYSRDFLLEIIEIARKHKLMIFADEIYDKVLYDGAVHTSIATLADDVLVVTFNGLSK
AYRVCGFRGGWMFLTGPKQQAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELILPGGRLLEQRDRAWELINQI
PGISCVKPKGAMYLFPKIDTKMYPIKDDQKMVLDFLVQEKVLLVQGSGFNWPKPDHFRIVTLPHVEDLEIAISRFERFIT
TYSQ
>Mature_404_residues
MQNIGMSSKLDNVCYDIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIRNLPTSQGYCDSKGIYSARKA
VVQYYQKKGIRSLDVEDVYIGNGASELIVMAMQALLNNGDEMLVPAPDYPLWTAAVALSGGKAVHYICDEEADWYPDLDD
IRSKITPKTRGIVLINPNNPTGAVYSRDFLLEIIEIARKHKLMIFADEIYDKVLYDGAVHTSIATLADDVLVVTFNGLSK
AYRVCGFRGGWMFLTGPKQQAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELILPGGRLLEQRDRAWELINQI
PGISCVKPKGAMYLFPKIDTKMYPIKDDQKMVLDFLVQEKVLLVQGSGFNWPKPDHFRIVTLPHVEDLEIAISRFERFIT
TYSQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=467, Percent_Identity=26.5524625267666, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI215599424, Length=370, Percent_Identity=28.6486486486486, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=28.6472148541114, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI4885351, Length=450, Percent_Identity=26.2222222222222, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI95147551, Length=261, Percent_Identity=24.5210727969349, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI169881279, Length=261, Percent_Identity=24.5210727969349, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI56713256, Length=287, Percent_Identity=26.4808362369338, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI56713254, Length=287, Percent_Identity=26.4808362369338, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI149944424, Length=350, Percent_Identity=24.2857142857143, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI187936925, Length=377, Percent_Identity=25.1989389920424, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI14211921, Length=377, Percent_Identity=25.1989389920424, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI169881281, Length=155, Percent_Identity=26.4516129032258, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=77.2277227722772, Blast_Score=679, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=377, Percent_Identity=27.5862068965517, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1786816, Length=234, Percent_Identity=24.7863247863248, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=29.1891891891892, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=459, Percent_Identity=26.797385620915, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=27.6450511945392, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=203, Percent_Identity=30.0492610837438, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=203, Percent_Identity=30.0492610837438, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=200, Percent_Identity=26, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323118, Length=360, Percent_Identity=29.4444444444444, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320317, Length=362, Percent_Identity=27.9005524861878, Blast_Score=132, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6322401, Length=245, Percent_Identity=28.1632653061224, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=28.6096256684492, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI45551451, Length=460, Percent_Identity=26.9565217391304, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641770, Length=460, Percent_Identity=26.9565217391304, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641760, Length=460, Percent_Identity=26.9565217391304, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641768, Length=460, Percent_Identity=26.9565217391304, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641766, Length=460, Percent_Identity=26.9565217391304, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641764, Length=460, Percent_Identity=26.9565217391304, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573069, Length=174, Percent_Identity=28.735632183908, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646114, Length=174, Percent_Identity=28.735632183908, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573067, Length=174, Percent_Identity=28.735632183908, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573065, Length=174, Percent_Identity=28.735632183908, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45220; Mature: 45220

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNIGMSSKLDNVCYDIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIR
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTSQGYCDSKGIYSARKAVVQYYQKKGIRSLDVEDVYIGNGASELIVMAMQALLNNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVALSGGKAVHYICDEEADWYPDLDDIRSKITPKTRGIVLINPNNP
EEEEECCCCCHHHHHEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSRDFLLEIIEIARKHKLMIFADEIYDKVLYDGAVHTSIATLADDVLVVTFNGLSK
CCCEEHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCHHH
AYRVCGFRGGWMFLTGPKQQAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELI
HHHHHCCCCCEEEEECCHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRDRAWELINQIPGISCVKPKGAMYLFPKIDTKMYPIKDDQKMVLDFLVQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCEEECCCCCHHHHHHHHHHCC
VLLVQGSGFNWPKPDHFRIVTLPHVEDLEIAISRFERFITTYSQ
EEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNIGMSSKLDNVCYDIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIR
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTSQGYCDSKGIYSARKAVVQYYQKKGIRSLDVEDVYIGNGASELIVMAMQALLNNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVALSGGKAVHYICDEEADWYPDLDDIRSKITPKTRGIVLINPNNP
EEEEECCCCCHHHHHEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSRDFLLEIIEIARKHKLMIFADEIYDKVLYDGAVHTSIATLADDVLVVTFNGLSK
CCCEEHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCHHH
AYRVCGFRGGWMFLTGPKQQAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELI
HHHHHCCCCCEEEEECCHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRDRAWELINQIPGISCVKPKGAMYLFPKIDTKMYPIKDDQKMVLDFLVQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCEEECCCCCHHHHHHHHHHCC
VLLVQGSGFNWPKPDHFRIVTLPHVEDLEIAISRFERFITTYSQ
EEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]