Click here to switch to the map view.

The map label for this gene is minE

Identifier: 227082090

GI number: 227082090

Start: 2049635

End: 2049898

Strand: Direct

Name: minE

Synonym: VCM66_1885

Alternate gene names: 227082090

Gene position: 2049635-2049898 (Clockwise)

Preceding gene: 227082089

Following gene: 227082091

Centisome position: 70.86

GC content: 47.73

Gene sequence:

>264_bases
ATGTCATTGCTGGAATTTTTCCGCCCACAGAAGAAGACTTCCGCGAGCGTTGCCAAAGAGCGTCTGCAGATCATTGTGGC
TGAGCGTCGTAGCCAAAACGATCCTGCACCCAGCTATTTGCCACAACTCAAAGAAGACATTCTGAAAGTGATTGCCAAAT
ACGTCGCGATTGACCCATCCATGGTCGAACTCTCTTTTGAGCATAAAGGCGATGATATCTCGGTGCTTGAGCTCAACGTC
AAACTGCCGGATGACGAAAAATAA

Upstream 100 bases:

>100_bases
CAAGATACGGTGGCACGTCTACTTGGTGAACAAGTTGAGTTTCGTTTCCTGACTGAAGCGAAGAAAGGTATTTTCAAACG
CTTATTCGGAGGTTAACGCT

Downstream 100 bases:

>100_bases
CCGCTTCAAGACCCTCATCGATGAGGGTCTTTTATTATCTCCCTCTGGTCTCTGCTCAACAGGCTCTCTCCAAACGATTT
GGCGTTGTCGTCTGTAGGCG

Product: cell division topological specificity factor MinE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 86

Protein sequence:

>87_residues
MSLLEFFRPQKKTSASVAKERLQIIVAERRSQNDPAPSYLPQLKEDILKVIAKYVAIDPSMVELSFEHKGDDISVLELNV
KLPDDEK

Sequences:

>Translated_87_residues
MSLLEFFRPQKKTSASVAKERLQIIVAERRSQNDPAPSYLPQLKEDILKVIAKYVAIDPSMVELSFEHKGDDISVLELNV
KLPDDEK
>Mature_86_residues
SLLEFFRPQKKTSASVAKERLQIIVAERRSQNDPAPSYLPQLKEDILKVIAKYVAIDPSMVELSFEHKGDDISVLELNVK
LPDDEK

Specific function: Prevents the cell division inhibition by proteins minC and minD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the l

COG id: COG0851

COG function: function code D; Septum formation topological specificity factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minE family

Homologues:

Organism=Escherichia coli, GI1787422, Length=87, Percent_Identity=62.0689655172414, Blast_Score=107, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINE_VIBCH (Q9KQN7)

Other databases:

- EMBL:   AE003852
- PIR:   D82136
- RefSeq:   NP_231595.1
- ProteinModelPortal:   Q9KQN7
- SMR:   Q9KQN7
- GeneID:   2613465
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC1961
- TIGR:   VC_1961
- HOGENOM:   HBG449956
- OMA:   AHERVEN
- ProtClustDB:   PRK00296
- HAMAP:   MF_00262
- InterPro:   IPR005527
- TIGRFAMs:   TIGR01215

Pfam domain/function: PF03776 MinE

EC number: NA

Molecular weight: Translated: 9912; Mature: 9780

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLEFFRPQKKTSASVAKERLQIIVAERRSQNDPAPSYLPQLKEDILKVIAKYVAIDPS
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
MVELSFEHKGDDISVLELNVKLPDDEK
CEEEEECCCCCCEEEEEEEEECCCCCC
>Mature Secondary Structure 
SLLEFFRPQKKTSASVAKERLQIIVAERRSQNDPAPSYLPQLKEDILKVIAKYVAIDPS
CHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
MVELSFEHKGDDISVLELNVKLPDDEK
CEEEEECCCCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301