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The map label for this gene is frvA [H]

Identifier: 227081949

GI number: 227081949

Start: 1897488

End: 1897928

Strand: Direct

Name: frvA [H]

Synonym: VCM66_1743

Alternate gene names: 227081949

Gene position: 1897488-1897928 (Clockwise)

Preceding gene: 227081948

Following gene: 227081950

Centisome position: 65.6

GC content: 37.41

Gene sequence:

>441_bases
ATGATCACCGAGCTCACCAACATCCATTTAATTAAAGGCAATCTTCAAGCAAATAGTAAAAATGAAGTTTTTGCAGAATT
GGCGCAAATGTTACTTGAGAATAACCGCATCAGTAACAAAGAGGATTTTTTAAACGACATTGAAATACGTGAAAGATTAA
GTGTCACGTCAATGGACGGCATCGCCTACCCACACTCAAAAAGTAAAGCCGTTACAAAACCTGCCATCGCTGTTGGTGTA
AAGCACGAAGGCATTGAATATGGAGATGAAGAAGGCATCAAACCGACCGTATTCTTCATGATTGCCTCTCCCGACAACGG
CGCAGACCACCATATTTATGTTCTTCAAGAATTATTCGGAAAATTTAGCGAAGAATTTATTGAAGATATTCATAACGCAA
AAAATGAACATCAGATCCTTAATATTTCAATTCAATCATAA

Upstream 100 bases:

>100_bases
GTGGTACAAATCTATAGTGAGTGAATTATTTTTGCTATTTCAGTAAAACTCGACATCCATTAATTTTAGCTCATCAGTTA
AATACTTTATGAGCCAATAA

Downstream 100 bases:

>100_bases
GGCGTGAAATTATGAGTACCCTAACCGCTCAAGCTACCAATAATAGTAGCAATTTCAAAAAACTCCTCAGTACCATGAAA
GGCCACCTTTTATTTGGCAC

Product: PTS system, fructose-specific IIA component

Products: NA

Alternate protein names: EIIBCA-Man; EII-Man; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component; Mannose permease IIC component; PTS system mannose-specific EIIC component; Mannose-specific phosphotransferase enzyme IIA component; PTS system mannose-specific EIIA component [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MITELTNIHLIKGNLQANSKNEVFAELAQMLLENNRISNKEDFLNDIEIRERLSVTSMDGIAYPHSKSKAVTKPAIAVGV
KHEGIEYGDEEGIKPTVFFMIASPDNGADHHIYVLQELFGKFSEEFIEDIHNAKNEHQILNISIQS

Sequences:

>Translated_146_residues
MITELTNIHLIKGNLQANSKNEVFAELAQMLLENNRISNKEDFLNDIEIRERLSVTSMDGIAYPHSKSKAVTKPAIAVGV
KHEGIEYGDEEGIKPTVFFMIASPDNGADHHIYVLQELFGKFSEEFIEDIHNAKNEHQILNISIQS
>Mature_146_residues
MITELTNIHLIKGNLQANSKNEVFAELAQMLLENNRISNKEDFLNDIEIRERLSVTSMDGIAYPHSKSKAVTKPAIAVGV
KHEGIEYGDEEGIKPTVFFMIASPDNGADHHIYVLQELFGKFSEEFIEDIHNAKNEHQILNISIQS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 16449; Mature: 16449

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITELTNIHLIKGNLQANSKNEVFAELAQMLLENNRISNKEDFLNDIEIRERLSVTSMDG
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
IAYPHSKSKAVTKPAIAVGVKHEGIEYGDEEGIKPTVFFMIASPDNGADHHIYVLQELFG
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHH
KFSEEFIEDIHNAKNEHQILNISIQS
HHHHHHHHHHHCCCCCCEEEEEEECC
>Mature Secondary Structure
MITELTNIHLIKGNLQANSKNEVFAELAQMLLENNRISNKEDFLNDIEIRERLSVTSMDG
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
IAYPHSKSKAVTKPAIAVGVKHEGIEYGDEEGIKPTVFFMIASPDNGADHHIYVLQELFG
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHH
KFSEEFIEDIHNAKNEHQILNISIQS
HHHHHHHHHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]