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The map label for this gene is nagA-2 [H]

Identifier: 227081928

GI number: 227081928

Start: 1878883

End: 1880019

Strand: Direct

Name: nagA-2 [H]

Synonym: VCM66_1721

Alternate gene names: 227081928

Gene position: 1878883-1880019 (Clockwise)

Preceding gene: 227081927

Following gene: 227081929

Centisome position: 64.96

GC content: 44.94

Gene sequence:

>1137_bases
ATGGCATTAAAGGCAATTTCAGCCACACGGCTTTTTGATGGAATTCAGTATTACGAGAATGCGGCAATGGTTTGGGAAGG
TTCACACATTCACTCCATTGTTCCTATTGAGTCTCTGACGGAGGATATTGAGCATCAACATTTTGATGGTGCATTGATCG
CTCCAGGATTCATTGACTTACAAGTTAATGGCGGTGGCGATGTCATGTTCAATAATGACATGACTCTTGCGGGTATTGAT
TCGATCTGCCGAGCACACAGAACTCACGGCACCGCCTATCTGCTTCCAACCTTAATCAGTGCAACACCGGAACACATCAA
CCGTGCACTTGATGCCATTCAATCTGCAATCGAAAATCAAGTCTCGGGTGTGTTGGGTATTCACTTAGAGGGGCCTTGGT
TAAACCCAGAAAAGAAAGGCGCTCATAACCCAGATCTGTTCTATTCCCCGACACCCGAACAACTTTCACAGTTTCACTGG
CCAACCAAAGGCAAAGTTCTTGTAACGGTCGCGGCTGAAAACCTCTCCATCGACTCACTAAAGTGGTTAAAGGATCATCA
TGTTACTCTCTCGTGTGGTCACAGTAATGCCACTACAGCCCAATTAACCACTGAGAAGTTAGCTCTCATTGATGGATTTA
CCCACTTATTTAATGCCATGTCGCCTTTTGAGAGTCGTGAACCCGGAGTTGTCGGTACAGCATTGAATACCGATCATGCT
TGGTGTTCAGTAATAACTGATGGAATTCATGTCCATCCACAAAGTTTTTTACTCGCTAAGCGAATCAAACCTAAAGACAA
ACTTCTTATTGTTACCGATGCCATGGCTAGCCTTGGCAGTGTGACTAGCCAGTTTGAATTGGATGGGGAAACCATTCGCG
TCATCGATAATAAACTGATTAATAGCAGAGGCAATCTTGCGGGAGCACACATCGGGATGGATGAATCGGTTGCCAATGTT
ATTCGTTGGGGAATCGCGGAAGATGAAGCATTAAAAATGGCCTCGTCTTATCCGGCTCAAGCAATTCAATGTGATGATTT
AGGGCAACTAAAACCCAATTATCGAGCCGCCGCCACTGTATTAAACTCCAAATATGAAAGCTTGGCTGTAGTCAGTGAAG
GCGTGCTCTACAACTGA

Upstream 100 bases:

>100_bases
TCAATCTAGGCCATCCGTATTTCACATCCCTGTCACTCCTGCTCATGGCGATTATGATGCTTGCCTACTCGGAGCAGCAT
TTCAGTTTAAGGAGTAAACG

Downstream 100 bases:

>100_bases
GCTATCGATCAAACATGCCTATCCGTTATTGACCAGATCGTTCACTATTCCAATGTTCAGCAGAGATCATTGGAATAGCT
CTTCCCAAAAAATCTATATG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MALKAISATRLFDGIQYYENAAMVWEGSHIHSIVPIESLTEDIEHQHFDGALIAPGFIDLQVNGGGDVMFNNDMTLAGID
SICRAHRTHGTAYLLPTLISATPEHINRALDAIQSAIENQVSGVLGIHLEGPWLNPEKKGAHNPDLFYSPTPEQLSQFHW
PTKGKVLVTVAAENLSIDSLKWLKDHHVTLSCGHSNATTAQLTTEKLALIDGFTHLFNAMSPFESREPGVVGTALNTDHA
WCSVITDGIHVHPQSFLLAKRIKPKDKLLIVTDAMASLGSVTSQFELDGETIRVIDNKLINSRGNLAGAHIGMDESVANV
IRWGIAEDEALKMASSYPAQAIQCDDLGQLKPNYRAAATVLNSKYESLAVVSEGVLYN

Sequences:

>Translated_378_residues
MALKAISATRLFDGIQYYENAAMVWEGSHIHSIVPIESLTEDIEHQHFDGALIAPGFIDLQVNGGGDVMFNNDMTLAGID
SICRAHRTHGTAYLLPTLISATPEHINRALDAIQSAIENQVSGVLGIHLEGPWLNPEKKGAHNPDLFYSPTPEQLSQFHW
PTKGKVLVTVAAENLSIDSLKWLKDHHVTLSCGHSNATTAQLTTEKLALIDGFTHLFNAMSPFESREPGVVGTALNTDHA
WCSVITDGIHVHPQSFLLAKRIKPKDKLLIVTDAMASLGSVTSQFELDGETIRVIDNKLINSRGNLAGAHIGMDESVANV
IRWGIAEDEALKMASSYPAQAIQCDDLGQLKPNYRAAATVLNSKYESLAVVSEGVLYN
>Mature_377_residues
ALKAISATRLFDGIQYYENAAMVWEGSHIHSIVPIESLTEDIEHQHFDGALIAPGFIDLQVNGGGDVMFNNDMTLAGIDS
ICRAHRTHGTAYLLPTLISATPEHINRALDAIQSAIENQVSGVLGIHLEGPWLNPEKKGAHNPDLFYSPTPEQLSQFHWP
TKGKVLVTVAAENLSIDSLKWLKDHHVTLSCGHSNATTAQLTTEKLALIDGFTHLFNAMSPFESREPGVVGTALNTDHAW
CSVITDGIHVHPQSFLLAKRIKPKDKLLIVTDAMASLGSVTSQFELDGETIRVIDNKLINSRGNLAGAHIGMDESVANVI
RWGIAEDEALKMASSYPAQAIQCDDLGQLKPNYRAAATVLNSKYESLAVVSEGVLYN

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=346, Percent_Identity=30.9248554913295, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI224922791, Length=348, Percent_Identity=30.7471264367816, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1786892, Length=376, Percent_Identity=33.2446808510638, Blast_Score=214, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI17553768, Length=320, Percent_Identity=30.3125, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI19920392, Length=315, Percent_Identity=33.015873015873, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281361140, Length=328, Percent_Identity=32.0121951219512, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41101; Mature: 40970

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKAISATRLFDGIQYYENAAMVWEGSHIHSIVPIESLTEDIEHQHFDGALIAPGFIDL
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEECCHHHHHHHHHHHCCCCEEECCCEEEE
QVNGGGDVMFNNDMTLAGIDSICRAHRTHGTAYLLPTLISATPEHINRALDAIQSAIENQ
EECCCCCEEECCCCEEECHHHHHHHHHCCCCEEHHHHHHHCCHHHHHHHHHHHHHHHHHH
VSGVLGIHLEGPWLNPEKKGAHNPDLFYSPTPEQLSQFHWPTKGKVLVTVAAENLSIDSL
HCCEEEEEEECCCCCCCCCCCCCCCCEECCCHHHHHHCCCCCCCCEEEEEEECCCCCHHH
KWLKDHHVTLSCGHSNATTAQLTTEKLALIDGFTHLFNAMSPFESREPGVVGTALNTDHA
HHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCH
WCSVITDGIHVHPQSFLLAKRIKPKDKLLIVTDAMASLGSVTSQFELDGETIRVIDNKLI
HHHHEECCEEECCHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCEEEECCCEEEEEHHHHH
NSRGNLAGAHIGMDESVANVIRWGIAEDEALKMASSYPAQAIQCDDLGQLKPNYRAAATV
CCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHH
LNSKYESLAVVSEGVLYN
HHCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALKAISATRLFDGIQYYENAAMVWEGSHIHSIVPIESLTEDIEHQHFDGALIAPGFIDL
CCCHHHHHHHHHHHHHHCCCEEEEECCCCEEECCHHHHHHHHHHHCCCCEEECCCEEEE
QVNGGGDVMFNNDMTLAGIDSICRAHRTHGTAYLLPTLISATPEHINRALDAIQSAIENQ
EECCCCCEEECCCCEEECHHHHHHHHHCCCCEEHHHHHHHCCHHHHHHHHHHHHHHHHHH
VSGVLGIHLEGPWLNPEKKGAHNPDLFYSPTPEQLSQFHWPTKGKVLVTVAAENLSIDSL
HCCEEEEEEECCCCCCCCCCCCCCCCEECCCHHHHHHCCCCCCCCEEEEEEECCCCCHHH
KWLKDHHVTLSCGHSNATTAQLTTEKLALIDGFTHLFNAMSPFESREPGVVGTALNTDHA
HHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCH
WCSVITDGIHVHPQSFLLAKRIKPKDKLLIVTDAMASLGSVTSQFELDGETIRVIDNKLI
HHHHEECCEEECCHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCEEEECCCEEEEEHHHHH
NSRGNLAGAHIGMDESVANVIRWGIAEDEALKMASSYPAQAIQCDDLGQLKPNYRAAATV
CCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHH
LNSKYESLAVVSEGVLYN
HHCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]