Click here to switch to the map view.

The map label for this gene is nanE [H]

Identifier: 227081926

GI number: 227081926

Start: 1877306

End: 1878028

Strand: Direct

Name: nanE [H]

Synonym: VCM66_1719

Alternate gene names: 227081926

Gene position: 1877306-1878028 (Clockwise)

Preceding gene: 227081925

Following gene: 227081927

Centisome position: 64.9

GC content: 47.16

Gene sequence:

>723_bases
ATGAGGCCCGTCGTGAGAAAGAATTTTTTGAATATCGAAGAGTTAAAGCGATTTTTAAACGGCCAAACTGTCGTTTCCAT
ACAACCTGTAACAGGCAGCCCACTCGATAAAACAGATTTCATTGTGGCGATGGCGATCGCCGTCGAACAAGCGGGTGCAA
AAGCGCTGCGCATTGAAGGTGTGAATAACGTGGCTGCTGTATCCGCCGCAGTAACAATTCCGATTATAGGTATCGTTAAG
CGTGACTTGCCTGATAGCCCAATTCGAATCACTCCTTTTGTTTCAGATGTTGATGGCTTAGCAAATGCTGGCGCAACGGT
CATTGCTTTTGATGCCACCGATAGAACACGCCCTGAAAGTCGAGAACGTATTGCGCAAGCAATCAAAAACACGGGATGTT
TTGCGATGGCCGATTGCTCCACATTCGAGGATGGATTATGGGCTAACTCACAAGGTGTTGAAATTGTTGGATCAACACTG
TCAGGCTATGTCGGAGATATTGAGCCCACGGTTCCAGATTTCCAACTTGTGAAAGCGTTTTCTGAAGCCGGCTTTTTTAC
CATGGCGGAAGGTCGATACAATACGCCTGAGTTAGCAGCGAAAGCTATTGAGTCTGGTGCGGTTGCCGTAACGGTTGGTT
CTGCATTGACTCGATTAGAAGTGGTTACTCAATGGTTCAATAACGCAACCCAAGCTGCGGGAGAAAGGAAATGCGCACAC
TAG

Upstream 100 bases:

>100_bases
CAAACCACCTTTTTTCAAAGTGTGATGGCGAACAAAATTTGGTTACAAGAGTCCTTTTGTTCATCAAGTCAGGAATTAAA
AACGTTTTTAGAAAAGAAAA

Downstream 100 bases:

>100_bases
CCATCGATATCGGCGGAACAAAAATAGCATTAGCGATTGTAGAAGAAGGTACGATCATACAGCGTTACCAGATAGCAACG
CCTGTGGTGCAGGACGTCAC

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRPVVRKNFLNIEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVEQAGAKALRIEGVNNVAAVSAAVTIPIIGIVK
RDLPDSPIRITPFVSDVDGLANAGATVIAFDATDRTRPESRERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTL
SGYVGDIEPTVPDFQLVKAFSEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWFNNATQAAGERKCAH

Sequences:

>Translated_240_residues
MRPVVRKNFLNIEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVEQAGAKALRIEGVNNVAAVSAAVTIPIIGIVK
RDLPDSPIRITPFVSDVDGLANAGATVIAFDATDRTRPESRERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTL
SGYVGDIEPTVPDFQLVKAFSEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWFNNATQAAGERKCAH
>Mature_240_residues
MRPVVRKNFLNIEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVEQAGAKALRIEGVNNVAAVSAAVTIPIIGIVK
RDLPDSPIRITPFVSDVDGLANAGATVIAFDATDRTRPESRERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTL
SGYVGDIEPTVPDFQLVKAFSEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWFNNATQAAGERKCAH

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=214, Percent_Identity=57.4766355140187, Blast_Score=227, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 25502; Mature: 25502

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPVVRKNFLNIEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVEQAGAKALRIEG
CCCCHHHHCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEC
VNNVAAVSAAVTIPIIGIVKRDLPDSPIRITPFVSDVDGLANAGATVIAFDATDRTRPES
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCEEEEEECCCCCCCHH
RERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTLSGYVGDIEPTVPDFQLVKAF
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEECHHCCCCCCCCCCCCHHHHHHHH
SEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWFNNATQAAGERKCAH
HHCCCEEEECCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRPVVRKNFLNIEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVEQAGAKALRIEG
CCCCHHHHCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEC
VNNVAAVSAAVTIPIIGIVKRDLPDSPIRITPFVSDVDGLANAGATVIAFDATDRTRPES
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCEEEEEECCCCCCCHH
RERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTLSGYVGDIEPTVPDFQLVKAF
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEECHHCCCCCCCCCCCCHHHHHHHH
SEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWFNNATQAAGERKCAH
HHCCCEEEECCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA