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The map label for this gene is aroA [H]

Identifier: 227081880

GI number: 227081880

Start: 1817658

End: 1818938

Strand: Reverse

Name: aroA [H]

Synonym: VCM66_1672

Alternate gene names: 227081880

Gene position: 1818938-1817658 (Counterclockwise)

Preceding gene: 227081886

Following gene: 227081878

Centisome position: 62.88

GC content: 50.74

Gene sequence:

>1281_bases
ATGGAAAGTTTGACTCTACAACCGATTGAACTCATCTCTGGGGAAGTGAATCTTCCCGGTTCCAAAAGCGTTTCAAACCG
TGCGCTCTTGCTGGCTGCGCTAGCTTCAGGCACGACTCGTCTTACTAACTTGCTCGATAGCGACGATATTCGTCATATGC
TCAATGCTTTGACCAAGCTGGGTGTGAACTATCGCCTCTCGGCCGATAAAACCACCTGTGAAGTAGAAGGTTTGGGCCAA
GCCTTTCACACGACTCAGCCATTAGAGCTGTTTTTAGGTAACGCAGGCACTGCAATGCGTCCGCTGGCGGCGGCGTTGTG
TCTTGGACAAGGTGACTATGTACTGACTGGTGAACCGCGCATGAAAGAGCGCCCGATTGGCCACTTAGTGGATGCTCTTC
GTCAAGCCGGCGCACAAATTGAGTATCTGGAGCAGGAAAACTTTCCGCCACTGCGTATTCAAGGGACGGGCTTACAAGCA
GGAACGGTGACTATCGATGGTTCTATCTCTAGTCAGTTTTTGACCGCCTTTCTTATGTCGGCACCGTTGGCGCAGGGCAA
AGTGACCATCAAGATCGTCGGTGAGCTGGTTTCTAAGCCTTACATCGACATTACACTGCACATCATGGAGCAGTTTGGTG
TTCAGGTGATCAACCACGATTATCAAGAATTTGTGATCCCAGCGGGGCAATCTTATGTGTCTCCGGGGCAGTTCCTCGTC
GAAGGTGATGCCTCTTCTGCTTCCTATTTCCTTGCTGCGGCTGCCATTAAAGGCGGTGAGGTAAAAGTGACCGGTATTGG
TAAAAACAGCATCCAAGGGGATATTCAATTTGCGGATGCATTGGAAAAGATGGGCGCGCAAATTGAGTGGGGCGATGATT
ATGTGATTGCTCGCCGTGGTGAGCTGAATGCGGTGGATCTCGATTTTAACCATATCCCAGATGCGGCGATGACGATAGCG
ACGACGGCACTCTTTGCCAAAGGCACCACGGCCATTCGTAACGTTTACAACTGGCGCGTAAAAGAGACGGATCGCTTGGC
AGCAATGGCCACCGAACTGCGTAAAGTGGGCGCGACAGTCGAAGAGGGGGAAGATTTCATTGTGATTACGCCTCCAACTA
AGCTCATCCATGCGGCAATCGATACCTATGACGATCACCGGATGGCGATGTGTTTTTCTCTGGTTGCGTTGAGCGATACG
CCAGTGACGATCAATGATCCGAAATGCACGTCAAAAACGTTCCCCGATTACTTTGACAAGTTTGCGCAGTTAAGCCGCTA
A

Upstream 100 bases:

>100_bases
GCGCTAGCGCATGAATTTGGTTAGTCTGCGGATACGAAGAATTTTCGCCGCGACCCATTACCACAAGGACTTTCAGCGGC
GCAAGGAAACACAACATCCA

Downstream 100 bases:

>100_bases
AGTGTCACTCTCTGCCCAAAACCGATGGCGATAAAATCGGTTTCGGAATAGATGTAAGTGATTGAAAAAAGCCTCATTAC
GAGGCTTTTATTATTTTTGT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MESLTLQPIELISGEVNLPGSKSVSNRALLLAALASGTTRLTNLLDSDDIRHMLNALTKLGVNYRLSADKTTCEVEGLGQ
AFHTTQPLELFLGNAGTAMRPLAAALCLGQGDYVLTGEPRMKERPIGHLVDALRQAGAQIEYLEQENFPPLRIQGTGLQA
GTVTIDGSISSQFLTAFLMSAPLAQGKVTIKIVGELVSKPYIDITLHIMEQFGVQVINHDYQEFVIPAGQSYVSPGQFLV
EGDASSASYFLAAAAIKGGEVKVTGIGKNSIQGDIQFADALEKMGAQIEWGDDYVIARRGELNAVDLDFNHIPDAAMTIA
TTALFAKGTTAIRNVYNWRVKETDRLAAMATELRKVGATVEEGEDFIVITPPTKLIHAAIDTYDDHRMAMCFSLVALSDT
PVTINDPKCTSKTFPDYFDKFAQLSR

Sequences:

>Translated_426_residues
MESLTLQPIELISGEVNLPGSKSVSNRALLLAALASGTTRLTNLLDSDDIRHMLNALTKLGVNYRLSADKTTCEVEGLGQ
AFHTTQPLELFLGNAGTAMRPLAAALCLGQGDYVLTGEPRMKERPIGHLVDALRQAGAQIEYLEQENFPPLRIQGTGLQA
GTVTIDGSISSQFLTAFLMSAPLAQGKVTIKIVGELVSKPYIDITLHIMEQFGVQVINHDYQEFVIPAGQSYVSPGQFLV
EGDASSASYFLAAAAIKGGEVKVTGIGKNSIQGDIQFADALEKMGAQIEWGDDYVIARRGELNAVDLDFNHIPDAAMTIA
TTALFAKGTTAIRNVYNWRVKETDRLAAMATELRKVGATVEEGEDFIVITPPTKLIHAAIDTYDDHRMAMCFSLVALSDT
PVTINDPKCTSKTFPDYFDKFAQLSR
>Mature_426_residues
MESLTLQPIELISGEVNLPGSKSVSNRALLLAALASGTTRLTNLLDSDDIRHMLNALTKLGVNYRLSADKTTCEVEGLGQ
AFHTTQPLELFLGNAGTAMRPLAAALCLGQGDYVLTGEPRMKERPIGHLVDALRQAGAQIEYLEQENFPPLRIQGTGLQA
GTVTIDGSISSQFLTAFLMSAPLAQGKVTIKIVGELVSKPYIDITLHIMEQFGVQVINHDYQEFVIPAGQSYVSPGQFLV
EGDASSASYFLAAAAIKGGEVKVTGIGKNSIQGDIQFADALEKMGAQIEWGDDYVIARRGELNAVDLDFNHIPDAAMTIA
TTALFAKGTTAIRNVYNWRVKETDRLAAMATELRKVGATVEEGEDFIVITPPTKLIHAAIDTYDDHRMAMCFSLVALSDT
PVTINDPKCTSKTFPDYFDKFAQLSR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=426, Percent_Identity=75.3521126760563, Blast_Score=649, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320332, Length=443, Percent_Identity=38.1489841986456, Blast_Score=250, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46102; Mature: 46102

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLTLQPIELISGEVNLPGSKSVSNRALLLAALASGTTRLTNLLDSDDIRHMLNALTKL
CCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEHHHCCHHHHHHHHCCHHHHHHHHHHHHC
GVNYRLSADKTTCEVEGLGQAFHTTQPLELFLGNAGTAMRPLAAALCLGQGDYVLTGEPR
CCCEEEECCCCEEEEHHCCHHHCCCCCHHEEECCCCCHHHHHHHHHHCCCCCEEEECCCC
MKERPIGHLVDALRQAGAQIEYLEQENFPPLRIQGTGLQAGTVTIDGSISSQFLTAFLMS
CCCCCHHHHHHHHHHCCCEEEEHHCCCCCCEEEEECCCEECEEEECCCCHHHHHHHHHHH
APLAQGKVTIKIVGELVSKPYIDITLHIMEQFGVQVINHDYQEFVIPAGQSYVSPGQFLV
CCCCCCCEEEEEEHHHHCCCCEEEHHHHHHHHCHHHCCCCCHHEEEECCCCCCCCCCEEE
EGDASSASYFLAAAAIKGGEVKVTGIGKNSIQGDIQFADALEKMGAQIEWGDDYVIARRG
ECCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECC
ELNAVDLDFNHIPDAAMTIATTALFAKGTTAIRNVYNWRVKETDRLAAMATELRKVGATV
CCEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCEECCHHHHHHHHHHHHHHCCHH
EEGEDFIVITPPTKLIHAAIDTYDDHRMAMCFSLVALSDTPVTINDPKCTSKTFPDYFDK
CCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHH
FAQLSR
HHHHCC
>Mature Secondary Structure
MESLTLQPIELISGEVNLPGSKSVSNRALLLAALASGTTRLTNLLDSDDIRHMLNALTKL
CCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEHHHCCHHHHHHHHCCHHHHHHHHHHHHC
GVNYRLSADKTTCEVEGLGQAFHTTQPLELFLGNAGTAMRPLAAALCLGQGDYVLTGEPR
CCCEEEECCCCEEEEHHCCHHHCCCCCHHEEECCCCCHHHHHHHHHHCCCCCEEEECCCC
MKERPIGHLVDALRQAGAQIEYLEQENFPPLRIQGTGLQAGTVTIDGSISSQFLTAFLMS
CCCCCHHHHHHHHHHCCCEEEEHHCCCCCCEEEEECCCEECEEEECCCCHHHHHHHHHHH
APLAQGKVTIKIVGELVSKPYIDITLHIMEQFGVQVINHDYQEFVIPAGQSYVSPGQFLV
CCCCCCCEEEEEEHHHHCCCCEEEHHHHHHHHCHHHCCCCCHHEEEECCCCCCCCCCEEE
EGDASSASYFLAAAAIKGGEVKVTGIGKNSIQGDIQFADALEKMGAQIEWGDDYVIARRG
ECCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECC
ELNAVDLDFNHIPDAAMTIATTALFAKGTTAIRNVYNWRVKETDRLAAMATELRKVGATV
CCEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCEECCHHHHHHHHHHHHHHCCHH
EEGEDFIVITPPTKLIHAAIDTYDDHRMAMCFSLVALSDTPVTINDPKCTSKTFPDYFDK
CCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHH
FAQLSR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA