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The map label for this gene is torC [H]

Identifier: 227081842

GI number: 227081842

Start: 1774311

End: 1775495

Strand: Reverse

Name: torC [H]

Synonym: VCM66_1633

Alternate gene names: 227081842

Gene position: 1775495-1774311 (Counterclockwise)

Preceding gene: 227081843

Following gene: 227081841

Centisome position: 61.38

GC content: 49.54

Gene sequence:

>1185_bases
ATGAAATCGTTAATTTTAAAAATGTGGCACACCATGACGCGTCCCGCGGTACACATTAGCTTGGGGGTATTGACTCTCGG
TGGCTTTATCGCTGGGGTAATTTTCTGGGGCGGCTTTAACACCGCTTTGGAAGCGACCAACACGGAAGAGTTCTGTATCA
GTTGTCACACCATGCGTGACAACGTGTACCAAGAGCTGCAAACCACAGTGCACTGGAAAAACCACTCTGGCGTGCGAGCG
ACCTGTCCTGATTGTCACGTCCCGCATGAGTGGACGGCGAAAATTGCACGTAAGATGCAAGCTTCAAAAGAAGTATTCGC
ACAGATCTTTGGTGATTTAGATACGCCAGAAAAGTTTGAAGAGCGCCGAATTGAATTGGCAAAACACGAATGGGATCGCT
TTGCGGCGAACAAATCTCTGGAGTGTAAAAACTGCCATAACTACGAATCGATGGATTTTGACCAGATGTCCGCAACGGCG
CGTATCCAAATGAAGCAAGCGGCAGAGCGCGATCAAAGCTGTATCGATTGTCACAAGGGGATTGCCCACAACTTGCCGAA
AAACATGGAGAGCTCAAGCGGCTTGATTGGTGAGCTCGAAGGTATGGCATCCAACACCAAATACTCCAATGGTGAAACCT
TAGTCAGCGTGCGTTTCCTCCCTGTGTATGAAGATGATCAAGCCAAAGTGGAAGCGGGTCTACTCAACCCTGCTTCTGAA
GTGAAAGTGCTGACTGAAAAAGGCGACATGATGCAAGTGGAGATCAACGGCTGGCGTAAATCGAAAGGCTTTGGCCGTGT
GATCCAAGAAGATTTCGGTATGAACATCGCGGTGGCGTCGCTACTGAAAGAGGCCGCCATGTCGGATGCGATTGTGACCA
CGGGTGAGCAGAAAGTCGATGACATGACGGGTCTACCTTGGGAGCAAGTCAGCGCGAAAGTGTGGATGAAAAAAGAAGCC
ATGCTGAACGACATCAACCCAGTTTGGGAAAAAGCGCGTGAAGCTTACAAGACCAACTGTTCTGTCTGTCACACCCAACC
GGATGAAGCGCACTTTGATGCCAACACTTGGCCTGGCATGTTCGACGGTATGTTGGCATTCGTCAACTTCGATACCGACA
GTGAAGCGCTGGTACTGAAGTACCTGCAAAAACACTCTTCAGATTTCGCTGAAGGCCACCACTAA

Upstream 100 bases:

>100_bases
TGGATGCTGCAGATGTTCGTGTTTGGTCCTCCAGGTCTGCACGGCGGTTTCTAACCACCTCCATTTCTACTGTTGAATGA
CTTAGCTAAGAGAAGAAAGC

Downstream 100 bases:

>100_bases
GCAACGTCATACGGAGTTATAACATGGCGATTACACGAAGAAGTTTTCTGAAAGGTGTCGCAACCACCAGTGCGGCGTCG
ATCATTGGCCCAAGCCTACT

Product: cytochrome c-type protein TorC

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKSLILKMWHTMTRPAVHISLGVLTLGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRDNVYQELQTTVHWKNHSGVRA
TCPDCHVPHEWTAKIARKMQASKEVFAQIFGDLDTPEKFEERRIELAKHEWDRFAANKSLECKNCHNYESMDFDQMSATA
RIQMKQAAERDQSCIDCHKGIAHNLPKNMESSSGLIGELEGMASNTKYSNGETLVSVRFLPVYEDDQAKVEAGLLNPASE
VKVLTEKGDMMQVEINGWRKSKGFGRVIQEDFGMNIAVASLLKEAAMSDAIVTTGEQKVDDMTGLPWEQVSAKVWMKKEA
MLNDINPVWEKAREAYKTNCSVCHTQPDEAHFDANTWPGMFDGMLAFVNFDTDSEALVLKYLQKHSSDFAEGHH

Sequences:

>Translated_394_residues
MKSLILKMWHTMTRPAVHISLGVLTLGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRDNVYQELQTTVHWKNHSGVRA
TCPDCHVPHEWTAKIARKMQASKEVFAQIFGDLDTPEKFEERRIELAKHEWDRFAANKSLECKNCHNYESMDFDQMSATA
RIQMKQAAERDQSCIDCHKGIAHNLPKNMESSSGLIGELEGMASNTKYSNGETLVSVRFLPVYEDDQAKVEAGLLNPASE
VKVLTEKGDMMQVEINGWRKSKGFGRVIQEDFGMNIAVASLLKEAAMSDAIVTTGEQKVDDMTGLPWEQVSAKVWMKKEA
MLNDINPVWEKAREAYKTNCSVCHTQPDEAHFDANTWPGMFDGMLAFVNFDTDSEALVLKYLQKHSSDFAEGHH
>Mature_394_residues
MKSLILKMWHTMTRPAVHISLGVLTLGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRDNVYQELQTTVHWKNHSGVRA
TCPDCHVPHEWTAKIARKMQASKEVFAQIFGDLDTPEKFEERRIELAKHEWDRFAANKSLECKNCHNYESMDFDQMSATA
RIQMKQAAERDQSCIDCHKGIAHNLPKNMESSSGLIGELEGMASNTKYSNGETLVSVRFLPVYEDDQAKVEAGLLNPASE
VKVLTEKGDMMQVEINGWRKSKGFGRVIQEDFGMNIAVASLLKEAAMSDAIVTTGEQKVDDMTGLPWEQVSAKVWMKKEA
MLNDINPVWEKAREAYKTNCSVCHTQPDEAHFDANTWPGMFDGMLAFVNFDTDSEALVLKYLQKHSSDFAEGHH

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=389, Percent_Identity=41.3881748071979, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1788530, Length=193, Percent_Identity=53.3678756476684, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI1788181, Length=350, Percent_Identity=30, Blast_Score=175, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 44382; Mature: 44382

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLILKMWHTMTRPAVHISLGVLTLGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRD
CHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHHH
NVYQELQTTVHWKNHSGVRATCPDCHVPHEWTAKIARKMQASKEVFAQIFGDLDTPEKFE
HHHHHHHHHEEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ERRIELAKHEWDRFAANKSLECKNCHNYESMDFDQMSATARIQMKQAAERDQSCIDCHKG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAHNLPKNMESSSGLIGELEGMASNTKYSNGETLVSVRFLPVYEDDQAKVEAGLLNPASE
HHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHCCCCCHHH
VKVLTEKGDMMQVEINGWRKSKGFGRVIQEDFGMNIAVASLLKEAAMSDAIVTTGEQKVD
HEEEECCCCEEEEEECCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHEECCCHHHH
DMTGLPWEQVSAKVWMKKEAMLNDINPVWEKAREAYKTNCSVCHTQPDEAHFDANTWPGM
HHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCH
FDGMLAFVNFDTDSEALVLKYLQKHSSDFAEGHH
HHCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKSLILKMWHTMTRPAVHISLGVLTLGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRD
CHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHHH
NVYQELQTTVHWKNHSGVRATCPDCHVPHEWTAKIARKMQASKEVFAQIFGDLDTPEKFE
HHHHHHHHHEEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ERRIELAKHEWDRFAANKSLECKNCHNYESMDFDQMSATARIQMKQAAERDQSCIDCHKG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAHNLPKNMESSSGLIGELEGMASNTKYSNGETLVSVRFLPVYEDDQAKVEAGLLNPASE
HHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHCCCCCHHH
VKVLTEKGDMMQVEINGWRKSKGFGRVIQEDFGMNIAVASLLKEAAMSDAIVTTGEQKVD
HEEEECCCCEEEEEECCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHEECCCHHHH
DMTGLPWEQVSAKVWMKKEAMLNDINPVWEKAREAYKTNCSVCHTQPDEAHFDANTWPGM
HHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCH
FDGMLAFVNFDTDSEALVLKYLQKHSSDFAEGHH
HHCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]