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The map label for this gene is torA

Identifier: 227081841

GI number: 227081841

Start: 1771825

End: 1774287

Strand: Reverse

Name: torA

Synonym: VCM66_1632

Alternate gene names: 227081841

Gene position: 1774287-1771825 (Counterclockwise)

Preceding gene: 227081842

Following gene: 227081838

Centisome position: 61.34

GC content: 51.44

Gene sequence:

>2463_bases
ATGGCGATTACACGAAGAAGTTTTCTGAAAGGTGTCGCAACCACCAGTGCGGCGTCGATCATTGGCCCAAGCCTACTGAC
CTCAGTTTCTGCCCAAGCGGCAGAAACCACGGGAACTTGGAAAGTCTCCGGTTCTCACTGGGGTGCCTTCCGCGCCCACA
TCTACGGCGGAAAGGTACAAGAGCTGAAAGCGTTGGAGTTGGATACCCACCCAACGGAAATGTTGAACGGCATTCAAGGC
ATTCTGTACAGCCCATCTCGCGTGCGTTACCCAATGGTGCGCCTCGATTGGTTGAAAAAACACAAATACAGTGCAGAAAC
GCGCGGTAACAACCGTTTTATCCGTGTGACTTGGGATGAGGCGATTGACCTATTCTACCGTGAATTAGAGCGTGTGCAGA
AGCAATACGGCCCTTGGGCACTGCACGCAGGCCAAACCGGTTGGAACCAAACCGGTGCTTTCCACAACTGTACCGCGATG
ATGCAACGCGCGGTGGGTATGCACGGTAACTACATCACCAAAGTCGGGGATTACTCGACTGGTGCTGGTCAAACCATCAT
GCCTTACGTACTGGGTTCAACCGAAGTTTACGCGCAAGGTACCTCTTGGAGCGAGATTTTAGACAACTCAGACAACATCA
TTCTGTGGGCAAACGATCCGGTGAAAAACCTGCAAGTGGGTTGGAACTGTGAAACGCACCAGTCTTTCGGCTATCTGGAT
CAACTGAAAGAGAAAGTCGCAAAAGGCGAGATCAACGTGGTTTCTGTTGACCCAGTGAAAAACAAAACGCAGCGTTTCTT
ACAAAACGATCACTTGTACATCAACCCACAAACTGACGTGGCGTTTATGCTGGCGCTCGCGCATGTGTTGTATACCGAAA
ATCTGTACGACAAGAAGTTCATTGAAACTTACTGCTTGGGATTTGAAGAGTTCATCCCTTACGTACTGGGTAAGAGCAAA
GATAAGGTTGAAAAAACGCCTGAGTGGGCAGCGACAATCTGTGGCGTGAAACCCGATGCGATCCGCGATTTCGCCCGTAT
GTTGGTCAATGGTCGTACTCAGCTGCTGTTTGGTTGGTGTATCCAACGTCAAGAGCACGGGGAGCAGCCGTACTGGATGG
GCGCGGTACTGGCGGCCATGATCGGTCAAATCGGTCTGCCGGGTGGCGGTATCTCTTATGGTCACCACTATTCAGGCATC
GGCGTACCTTCAACGGGGTTTGCGGGTCCTGGCGGCTTCCCACGTAACCTTGACCAAGGTGCGAAGCCGAAGTGGGATAA
CAATGACTTCAACGGTTACAGCCGCACGATTCCGGTTGCTCGCTGGATTGATGCGATTCTCGAACCGGGTAAGAAGATCA
ACCACAACGGAAATACAGTCACGCTGCCCGGTTTCAAGATGATGGTGATTTCGGGTTGTAATCCTTGGCACCACCATCAA
GACCGCAACAAAATGAAGCGTGCGTTCCAGAAACTGGAGACTGTGGTGACGATTGATTTCAGTTGGACGGCAACCTGCCG
CTTTTCTGACATCGTACTGCCTGCTTGCACCCAGTGGGAACGTAACGACATCGACTCTTACGGTTCCTACTCCGGTAAAG
GCCTGATTGCGATGCATCGTTTGGTTGACCCGCTGTTCCAGTCACGTACTGACTTTGAAATCATGACCGAGCTGACTCGT
CGTTTTGGCCGTGAAAAAGAGTACACCCGTGGCATGGATGAGATGGAGTGGGTACGTTCACTGTATGACGAGTGTAAGAA
AGCCAACGAAGGTAAATTTGCCATGCCAGAATTCGAAGAGTTCTGGGAAAAAGGCTTCCTTGATTTTGGTACAGGCACAC
CTTGGGTTCGTCATGCGGATTTCCGCAAAGATCCTGAAATCAATGCATTGGGTACGCCTTCTGGTTTTATCGAAATTACG
TCACGTAAGATCGGTCGCTACGGTTATGAACACTGCCAAGAACACCCAATGTGGTTTGAGAAAACCGAACGTTCACACGG
GGGGCCGGGCTCTGACAAACATCCGTTCTGGTTGCAATCATGCCACCCAGATAAGCGTCTGCACTCACAAATGTGTGAAG
CCGAAGCATTCCGCGCGACTTACGCAGTGCAGGGGCGTGAGCCAGTGTACATCAACCCACTGGATGCGAAAGCCAAAGGT
ATTAAAGATGGCGATCTGGTGCGTGTATTCAACGACCGTGGTCAGCTATTGGCGGGAGCGGTGCTGAGTGACAGCTATCC
ACGTGGCGTGATCCGCATTGAAGAGGGGGCTTGGTATGGCCCGCTGACTGAGAAAGTTGGGGCGATCTGTACTTACGGCG
ATCCCAATACACTGACTCTGGATCTTGGTACGTCAGAGCTGGCGCAAGCCACTTCTGCCAATACCTGTATCGTTGATTTT
GAGAAATTCCGTGGTGAAGTGCCTCCTGTAACCTCATTCGGTGGCCCAATCGAAGTCATCTAG

Upstream 100 bases:

>100_bases
TCGATACCGACAGTGAAGCGCTGGTACTGAAGTACCTGCAAAAACACTCTTCAGATTTCGCTGAAGGCCACCACTAAGCA
ACGTCATACGGAGTTATAAC

Downstream 100 bases:

>100_bases
TCATCTAGTCATCTCTTTAACGTAAAATGCGCGTTATCCCTCAAGCCAGCGTTCAACGCTGGCTTTTTTCTTCTCTTTTA
TCCGTAAATCCGCTTAATCT

Product: trimethylamine-N-oxide reductase

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase

Number of amino acids: Translated: 820; Mature: 819

Protein sequence:

>820_residues
MAITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQELKALELDTHPTEMLNGIQG
ILYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDEAIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAM
MQRAVGMHGNYITKVGDYSTGAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLD
QLKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKFIETYCLGFEEFIPYVLGKSK
DKVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWCIQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGI
GVPSTGFAGPGGFPRNLDQGAKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQ
DRNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHRLVDPLFQSRTDFEIMTELTR
RFGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEEFWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEIT
SRKIGRYGYEHCQEHPMWFEKTERSHGGPGSDKHPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPLDAKAKG
IKDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTLDLGTSELAQATSANTCIVDF
EKFRGEVPPVTSFGGPIEVI

Sequences:

>Translated_820_residues
MAITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQELKALELDTHPTEMLNGIQG
ILYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDEAIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAM
MQRAVGMHGNYITKVGDYSTGAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLD
QLKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKFIETYCLGFEEFIPYVLGKSK
DKVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWCIQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGI
GVPSTGFAGPGGFPRNLDQGAKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQ
DRNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHRLVDPLFQSRTDFEIMTELTR
RFGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEEFWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEIT
SRKIGRYGYEHCQEHPMWFEKTERSHGGPGSDKHPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPLDAKAKG
IKDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTLDLGTSELAQATSANTCIVDF
EKFRGEVPPVTSFGGPIEVI
>Mature_819_residues
AITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQELKALELDTHPTEMLNGIQGI
LYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDEAIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAMM
QRAVGMHGNYITKVGDYSTGAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLDQ
LKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKFIETYCLGFEEFIPYVLGKSKD
KVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWCIQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGIG
VPSTGFAGPGGFPRNLDQGAKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQD
RNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHRLVDPLFQSRTDFEIMTELTRR
FGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEEFWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEITS
RKIGRYGYEHCQEHPMWFEKTERSHGGPGSDKHPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPLDAKAKGI
KDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTLDLGTSELAQATSANTCIVDFE
KFRGEVPPVTSFGGPIEVI

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787231, Length=836, Percent_Identity=52.0334928229665, Blast_Score=882, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=825, Percent_Identity=38.1818181818182, Blast_Score=580, Evalue=1e-166,
Organism=Escherichia coli, GI145693196, Length=786, Percent_Identity=37.9134860050891, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI87081797, Length=869, Percent_Identity=28.078250863061, Blast_Score=285, Evalue=1e-77,
Organism=Escherichia coli, GI1787870, Length=863, Percent_Identity=27.8099652375435, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI171474008, Length=862, Percent_Identity=26.5661252900232, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI3868721, Length=697, Percent_Identity=22.9555236728838, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TORA_VIBCH (Q9KRF0)

Other databases:

- EMBL:   AE003852
- PIR:   G82168
- RefSeq:   NP_231328.1
- ProteinModelPortal:   Q9KRF0
- SMR:   Q9KRF0
- GeneID:   2613823
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC1692
- TIGR:   VC_1692
- HOGENOM:   HBG304064
- OMA:   GRVSEIK
- ProtClustDB:   PRK15102
- BRENDA:   1.7.2.3
- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887
- Gene3D:   G3DSA:2.40.40.20
- TIGRFAMs:   TIGR01409
- TIGRFAMs:   TIGR02164

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding; SSF50692 Asp_decarb_fold

EC number: =1.7.2.3

Molecular weight: Translated: 92306; Mature: 92174

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1; PS00490 MOLYBDOPTERIN_PROK_2; PS00932 MOLYBDOPTERIN_PROK_3; PS51318 TAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQ
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCHH
ELKALELDTHPTEMLNGIQGILYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDE
HHEEEECCCCHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
AIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAMMQRAVGMHGNYITKVGDYST
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
GAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLD
CCCCEEEHEEECCCEEEECCCCHHHHHCCCCCEEEEECCCCCCCEECCCCCCCCCCCHHH
QLKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKF
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHH
IETYCLGFEEFIPYVLGKSKDKVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWC
HHHHHCCHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
IQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGIGVPSTGFAGPGGFPRNLDQG
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQ
CCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCEECCCCCEEEECCEEEEEEECCCCHHHCC
DRNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHR
HHHHHHHHHHHHHEEEEEEECEEEEEEECCEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
LVDPLFQSRTDFEIMTELTRRFGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEE
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
FWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEITSRKIGRYGYEHCQEHPMWFE
HHHCCCEECCCCCCCEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHH
KTERSHGGPGSDKHPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPLDAKAKG
HHCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCHHCC
IKDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTL
CCCCCEEEEECCCCCEEEHHHHCCCCCCCEEEECCCCCCCCHHHHHCCEEECCCCCEEEE
DLGTSELAQATSANTCIVDFEKFRGEVPPVTSFGGPIEVI
ECCCHHHHHHCCCCEEEEEHHHHCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
AITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQ
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCHH
ELKALELDTHPTEMLNGIQGILYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDE
HHEEEECCCCHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
AIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAMMQRAVGMHGNYITKVGDYST
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
GAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLD
CCCCEEEHEEECCCEEEECCCCHHHHHCCCCCEEEEECCCCCCCEECCCCCCCCCCCHHH
QLKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKF
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHH
IETYCLGFEEFIPYVLGKSKDKVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWC
HHHHHCCHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
IQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGIGVPSTGFAGPGGFPRNLDQG
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQ
CCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCEECCCCCEEEECCEEEEEEECCCCHHHCC
DRNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHR
HHHHHHHHHHHHHEEEEEEECEEEEEEECCEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
LVDPLFQSRTDFEIMTELTRRFGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEE
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
FWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEITSRKIGRYGYEHCQEHPMWFE
HHHCCCEECCCCCCCEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHH
KTERSHGGPGSDKHPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPLDAKAKG
HHCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCHHCC
IKDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTL
CCCCCEEEEECCCCCEEEHHHHCCCCCCCEEEECCCCCCCCHHHHHCCEEECCCCCEEEE
DLGTSELAQATSANTCIVDFEKFRGEVPPVTSFGGPIEVI
ECCCHHHHHHCCCCEEEEEHHHHCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301