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The map label for this gene is glpR [H]

Identifier: 227081708

GI number: 227081708

Start: 1613369

End: 1614130

Strand: Direct

Name: glpR [H]

Synonym: VCM66_1494

Alternate gene names: 227081708

Gene position: 1613369-1614130 (Clockwise)

Preceding gene: 227081707

Following gene: 227081709

Centisome position: 55.78

GC content: 48.82

Gene sequence:

>762_bases
GTGACTTTATTATCCCACCGCCAAAAACAGATCTTGGAATACTTGCAACAAACTCACGGGGTGCTTTCGAGCGCCCTACT
TTCGGAACGCTTTGAGGTGTCGGTACAAACCATTCGCAAAGATATGAATGATTTGAGCGATAAAGGCATGGTGCGCCGCG
TGCATGGCGGCATTTCCCTGCCCAGTCCGAATGACAATTTATCGTTCAGTAATCGCGATTTGATCAACCTGACAGCAAAA
CAGCGAATCGCGCAGAGGGTGGCGCAAGAATTACCGGAAGGATGCAGTATTTTTCTGGGTATCGGGACAACCCCGAAACA
AGTGGCGCAAGCGCTGCTCGATCATCCCGGTTTGACTGTGGTGACCAACAACCTCAATGCCGCACTGACCTTAAGCCGTA
ACCCCAACATCAATTTGCACCTTGCGGGCGGGCTGGTTCGCCATTCCGATGAAGATACCGTCGGCGAAGCGACAACCCGC
TTTTATCGTAGCTTTAATATTAAGGTTGGAATTTTTGGTGTAGGCGGGCTCAATTCTCGCGGTCAATTGCTTGATTTTAC
GCCAGAAGAAGCCAATTTAACCCGCGCCATCATAGAACATAGCGAACAGTGTTGGTTAGTTGCAGACAAAAGCAAATTAG
AGCGTTATGCTCCCGTGGTCAGTGGTGAACTGTCTGAAATGCATCGCCTCTTCGTCGATAAAAGTACGCCTGCTTTTCAA
CAGTTGTCCCTTTTGTACCACGTCGAACTTATTGAATCGTGA

Upstream 100 bases:

>100_bases
ACAAGGTAAACGCTTTGTCCAGTCACACCGTTCTTGTACACAGAGCAGCAAAGTCGCTAGCACTCGTCAGCAATAAAATT
CGTCAACAGTAAGGAAGCTT

Downstream 100 bases:

>100_bases
TTTGAGTGTGATTCTCACTAAGGAAGCATGATGCCTTCAATCATCGTCGGCCACCGTGGGGTGGCTGGAACGTATCCAGA
AAATACCCGTGTCAGTGTAC

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTLLSHRQKQILEYLQQTHGVLSSALLSERFEVSVQTIRKDMNDLSDKGMVRRVHGGISLPSPNDNLSFSNRDLINLTAK
QRIAQRVAQELPEGCSIFLGIGTTPKQVAQALLDHPGLTVVTNNLNAALTLSRNPNINLHLAGGLVRHSDEDTVGEATTR
FYRSFNIKVGIFGVGGLNSRGQLLDFTPEEANLTRAIIEHSEQCWLVADKSKLERYAPVVSGELSEMHRLFVDKSTPAFQ
QLSLLYHVELIES

Sequences:

>Translated_253_residues
MTLLSHRQKQILEYLQQTHGVLSSALLSERFEVSVQTIRKDMNDLSDKGMVRRVHGGISLPSPNDNLSFSNRDLINLTAK
QRIAQRVAQELPEGCSIFLGIGTTPKQVAQALLDHPGLTVVTNNLNAALTLSRNPNINLHLAGGLVRHSDEDTVGEATTR
FYRSFNIKVGIFGVGGLNSRGQLLDFTPEEANLTRAIIEHSEQCWLVADKSKLERYAPVVSGELSEMHRLFVDKSTPAFQ
QLSLLYHVELIES
>Mature_252_residues
TLLSHRQKQILEYLQQTHGVLSSALLSERFEVSVQTIRKDMNDLSDKGMVRRVHGGISLPSPNDNLSFSNRDLINLTAKQ
RIAQRVAQELPEGCSIFLGIGTTPKQVAQALLDHPGLTVVTNNLNAALTLSRNPNINLHLAGGLVRHSDEDTVGEATTRF
YRSFNIKVGIFGVGGLNSRGQLLDFTPEEANLTRAIIEHSEQCWLVADKSKLERYAPVVSGELSEMHRLFVDKSTPAFQQ
LSLLYHVELIES

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=247, Percent_Identity=40.4858299595142, Blast_Score=183, Evalue=8e-48,
Organism=Escherichia coli, GI87082344, Length=232, Percent_Identity=33.6206896551724, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI226510968, Length=234, Percent_Identity=32.9059829059829, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789059, Length=238, Percent_Identity=29.8319327731092, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1789519, Length=241, Percent_Identity=24.896265560166, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788069, Length=214, Percent_Identity=26.6355140186916, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789170, Length=235, Percent_Identity=28.0851063829787, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790753, Length=236, Percent_Identity=26.6949152542373, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28081; Mature: 27950

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLSHRQKQILEYLQQTHGVLSSALLSERFEVSVQTIRKDMNDLSDKGMVRRVHGGISL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
PSPNDNLSFSNRDLINLTAKQRIAQRVAQELPEGCSIFLGIGTTPKQVAQALLDHPGLTV
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCEE
VTNNLNAALTLSRNPNINLHLAGGLVRHSDEDTVGEATTRFYRSFNIKVGIFGVGGLNSR
EECCCCEEEEECCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCC
GQLLDFTPEEANLTRAIIEHSEQCWLVADKSKLERYAPVVSGELSEMHRLFVDKSTPAFQ
CCEEECCCCHHHHHHHHHHCCCCEEEEECHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHH
QLSLLYHVELIES
HHHHHHHHEECCC
>Mature Secondary Structure 
TLLSHRQKQILEYLQQTHGVLSSALLSERFEVSVQTIRKDMNDLSDKGMVRRVHGGISL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
PSPNDNLSFSNRDLINLTAKQRIAQRVAQELPEGCSIFLGIGTTPKQVAQALLDHPGLTV
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCEE
VTNNLNAALTLSRNPNINLHLAGGLVRHSDEDTVGEATTRFYRSFNIKVGIFGVGGLNSR
EECCCCEEEEECCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCC
GQLLDFTPEEANLTRAIIEHSEQCWLVADKSKLERYAPVVSGELSEMHRLFVDKSTPAFQ
CCEEECCCCHHHHHHHHHHCCCCEEEEECHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHH
QLSLLYHVELIES
HHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]