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The map label for this gene is atoS [H]

Identifier: 227081679

GI number: 227081679

Start: 1582496

End: 1584529

Strand: Reverse

Name: atoS [H]

Synonym: VCM66_1463

Alternate gene names: 227081679

Gene position: 1584529-1582496 (Counterclockwise)

Preceding gene: 227081680

Following gene: 227081678

Centisome position: 54.78

GC content: 47.64

Gene sequence:

>2034_bases
ATGAAAGCTAAATGGGCTTGGTGGCAAAAATGGCGACACCGTTTTCAAACCACCGTGCGCTATCGGCTGTGGATTCTGAC
CTCAGCGCCAATTTTTCTCACACTGCTGGCGCTGATTGCGATCACCATTTACTGGTCACTGCATTACACCTGGAACAGTG
CTTTAATTGATGTGTCTGAGCGGTTAGGCGTGGCGCAAAACAGTGTAACTCTACTGCAACAGAAACAAGCCAATCACGTT
CGCGCGTTTGCAGAATCGTACGATTTTCGCAAGCGTCTGCAAGAGCCGGAAACCCTCAGTACTTTGCCACGTTGGGTGCA
AAATCAAAAAAATCGCTATGGCTTAGATTTCTTAAGTTTTGAGCGTGTGGATAGCTTAGAGCAGAAGTTTCGCTATCTCG
ATCTCACCAAGCGTGAATCCTTCTTTGATGTACTTAGTGCCGATGAGCTAGAAAAGCTCGATCCGGATTTAGCTAAGCAA
GCGCAAATCCCGATTCTTAATTCTCAACAGATCGAAACTCGGGGATTAGTCAGTCGTACCGTGATTCCAGTGCGCAATGA
CTTCGGTGAGATCATAGGTTTTTTGGATGGTGGTTTACTGCTCAATAACAGCACAACCTTAGTCGATCAAATTCGAGATC
TCATCTACCCAAGTCATCAAGATCAGCTTCGCCCAACGGGCACTTTAACCCTGTTTTTGGATGACTTACGCGTCAGCACC
AACGTGCCTTTAGACAGTAATATCCATGCAGGTCGCGCGATAGGCACACGGGTGTCATCCGAAGTGTTTAATCAAGTGCT
CAAAGGTGGTCAGCAGTGGGTTAATCTGGCGTATGTGTATGATGCTTGGTACATCACCGCGTATGAGCCGATTCGCGATC
AATACCACAACGAAATTGGCATGCTGTACACCGGCTACTTAATGTGGCCGTTTTTAAAAGCTTACGTGACCAATATTTTA
GAAGTCGGGATCATCACGCTTTTCCTGCTGGTGATTTCAGGCCTGTTTGTGTACCGTGGCTCGCGCGATCTGTTTCGTCC
TATCGAGCGCATTCACCGTGTAGTGAAAATGGTGCAACTTGGTAAAAACCAGCGTATTGGTCAAATTGGGCTTGATGACA
AACATGAACTCGCTCAGCTTGCGAAGCAATTCGACAACATGCTGGATCAGTTGCAGCAACGGAATGAAGAAATCGTGCAA
GCCGCGCATGAGTTAGAAGCAAAAGTGCAATCGCGCACCGCCAGTTTGCAAGAGAAAACCGCGCAGCTTGAGCACCACAT
TGCCTTGCTTAACCAAACGCGCAATAAGTTAGTGGTGCATGAAAAACTGGCGGCACTTGGTGAGCTAACCGCGGGGATTG
CCCATGAAATCAATAACCCTACCGCCGTGATTCTCGGTAATACCGAGTTAATTCGTTTTGAGCTTGGTGCTGATGCGAGC
AGAGTCGAAGAAGAAATTGATGCCATCTTGCTGCAAATCGAGCGGATCCGAAACATCACGCGCAGCTTGTTGCAATACAG
TCGCCAAGGCGGAGTGCAGGACGAAATCACGTGGCAACACGTCAATCCGATCATTGATGAGAGTATTACCTTAGTCAAAA
CTGGTTCGAAAAAGCGCGATATTGAATTTGTGCTGGAACTGAAAGCGCACAATTCGGTGGAGGTGAATCGCCATCAACTG
CTGCAAATTCTGGTTAACCTACAGATGAACGCGATTCATGCCATGAACGGCAAAGGCCGCATCACGATACGTAGCGAAGA
TTGGGTTGAAGAGGGGCAAAACCGCGGAGCGGTGATCCACATTGAAGATCAAGGTTGTGGCATTAAGCCAGAAAACCTCA
AACGTATTTTCGATCCGTTTTATACCACCAAACGTGAGGGGACAGGGCTTGGGCTTTCGGTTTCACAAAGTTTGCTTAGC
CAGTCTGGCGGAGAAATTAAAGTGCAGTCTGAATTGGGCGTGGGTAGCACTTTCAGTATCTTCCTGCCTTCCAAAAATGA
AGCGAAACTTCGCGAGACCTTGCTGCTTCAATAA

Upstream 100 bases:

>100_bases
CTGCATGAGGGCAATAAATCGGCCGCCGCCCGCGATTTAGGCGTGGCACGTAAAACGTTGGAGCGTAAATACAAAGAGTG
GGAAAGCGAGGATCTCAGCC

Downstream 100 bases:

>100_bases
TCCCCCTACGAAAAGCTCGTTATTTTGTTGGTCATTTCACTTGAGATGACTGACTTTCATGCGCGTTATGTAAATCAGGG
CTTGTAGTCTGGGCGCTGAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MKAKWAWWQKWRHRFQTTVRYRLWILTSAPIFLTLLALIAITIYWSLHYTWNSALIDVSERLGVAQNSVTLLQQKQANHV
RAFAESYDFRKRLQEPETLSTLPRWVQNQKNRYGLDFLSFERVDSLEQKFRYLDLTKRESFFDVLSADELEKLDPDLAKQ
AQIPILNSQQIETRGLVSRTVIPVRNDFGEIIGFLDGGLLLNNSTTLVDQIRDLIYPSHQDQLRPTGTLTLFLDDLRVST
NVPLDSNIHAGRAIGTRVSSEVFNQVLKGGQQWVNLAYVYDAWYITAYEPIRDQYHNEIGMLYTGYLMWPFLKAYVTNIL
EVGIITLFLLVISGLFVYRGSRDLFRPIERIHRVVKMVQLGKNQRIGQIGLDDKHELAQLAKQFDNMLDQLQQRNEEIVQ
AAHELEAKVQSRTASLQEKTAQLEHHIALLNQTRNKLVVHEKLAALGELTAGIAHEINNPTAVILGNTELIRFELGADAS
RVEEEIDAILLQIERIRNITRSLLQYSRQGGVQDEITWQHVNPIIDESITLVKTGSKKRDIEFVLELKAHNSVEVNRHQL
LQILVNLQMNAIHAMNGKGRITIRSEDWVEEGQNRGAVIHIEDQGCGIKPENLKRIFDPFYTTKREGTGLGLSVSQSLLS
QSGGEIKVQSELGVGSTFSIFLPSKNEAKLRETLLLQ

Sequences:

>Translated_677_residues
MKAKWAWWQKWRHRFQTTVRYRLWILTSAPIFLTLLALIAITIYWSLHYTWNSALIDVSERLGVAQNSVTLLQQKQANHV
RAFAESYDFRKRLQEPETLSTLPRWVQNQKNRYGLDFLSFERVDSLEQKFRYLDLTKRESFFDVLSADELEKLDPDLAKQ
AQIPILNSQQIETRGLVSRTVIPVRNDFGEIIGFLDGGLLLNNSTTLVDQIRDLIYPSHQDQLRPTGTLTLFLDDLRVST
NVPLDSNIHAGRAIGTRVSSEVFNQVLKGGQQWVNLAYVYDAWYITAYEPIRDQYHNEIGMLYTGYLMWPFLKAYVTNIL
EVGIITLFLLVISGLFVYRGSRDLFRPIERIHRVVKMVQLGKNQRIGQIGLDDKHELAQLAKQFDNMLDQLQQRNEEIVQ
AAHELEAKVQSRTASLQEKTAQLEHHIALLNQTRNKLVVHEKLAALGELTAGIAHEINNPTAVILGNTELIRFELGADAS
RVEEEIDAILLQIERIRNITRSLLQYSRQGGVQDEITWQHVNPIIDESITLVKTGSKKRDIEFVLELKAHNSVEVNRHQL
LQILVNLQMNAIHAMNGKGRITIRSEDWVEEGQNRGAVIHIEDQGCGIKPENLKRIFDPFYTTKREGTGLGLSVSQSLLS
QSGGEIKVQSELGVGSTFSIFLPSKNEAKLRETLLLQ
>Mature_677_residues
MKAKWAWWQKWRHRFQTTVRYRLWILTSAPIFLTLLALIAITIYWSLHYTWNSALIDVSERLGVAQNSVTLLQQKQANHV
RAFAESYDFRKRLQEPETLSTLPRWVQNQKNRYGLDFLSFERVDSLEQKFRYLDLTKRESFFDVLSADELEKLDPDLAKQ
AQIPILNSQQIETRGLVSRTVIPVRNDFGEIIGFLDGGLLLNNSTTLVDQIRDLIYPSHQDQLRPTGTLTLFLDDLRVST
NVPLDSNIHAGRAIGTRVSSEVFNQVLKGGQQWVNLAYVYDAWYITAYEPIRDQYHNEIGMLYTGYLMWPFLKAYVTNIL
EVGIITLFLLVISGLFVYRGSRDLFRPIERIHRVVKMVQLGKNQRIGQIGLDDKHELAQLAKQFDNMLDQLQQRNEEIVQ
AAHELEAKVQSRTASLQEKTAQLEHHIALLNQTRNKLVVHEKLAALGELTAGIAHEINNPTAVILGNTELIRFELGADAS
RVEEEIDAILLQIERIRNITRSLLQYSRQGGVQDEITWQHVNPIIDESITLVKTGSKKRDIEFVLELKAHNSVEVNRHQL
LQILVNLQMNAIHAMNGKGRITIRSEDWVEEGQNRGAVIHIEDQGCGIKPENLKRIFDPFYTTKREGTGLGLSVSQSLLS
QSGGEIKVQSELGVGSTFSIFLPSKNEAKLRETLLLQ

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=314, Percent_Identity=32.1656050955414, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=34.3478260869565, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87081816, Length=273, Percent_Identity=30.03663003663, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=30.2127659574468, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789149, Length=347, Percent_Identity=25.3602305475504, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786600, Length=256, Percent_Identity=25.78125, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=25.2136752136752, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=25.5506607929515, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=26.8398268398268, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=29.5652173913043, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77501; Mature: 77501

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKWAWWQKWRHRFQTTVRYRLWILTSAPIFLTLLALIAITIYWSLHYTWNSALIDVSE
CCCCHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHEEEEECCHHEEHHH
RLGVAQNSVTLLQQKQANHVRAFAESYDFRKRLQEPETLSTLPRWVQNQKNRYGLDFLSF
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHH
ERVDSLEQKFRYLDLTKRESFFDVLSADELEKLDPDLAKQAQIPILNSQQIETRGLVSRT
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHC
VIPVRNDFGEIIGFLDGGLLLNNSTTLVDQIRDLIYPSHQDQLRPTGTLTLFLDDLRVST
EECCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECEEEEC
NVPLDSNIHAGRAIGTRVSSEVFNQVLKGGQQWVNLAYVYDAWYITAYEPIRDQYHNEIG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEEEEEEEEEEEEEHHHHHHHHCHHH
MLYTGYLMWPFLKAYVTNILEVGIITLFLLVISGLFVYRGSRDLFRPIERIHRVVKMVQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GKNQRIGQIGLDDKHELAQLAKQFDNMLDQLQQRNEEIVQAAHELEAKVQSRTASLQEKT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLEHHIALLNQTRNKLVVHEKLAALGELTAGIAHEINNPTAVILGNTELIRFELGADAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCHH
RVEEEIDAILLQIERIRNITRSLLQYSRQGGVQDEITWQHVNPIIDESITLVKTGSKKRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHCCCEEEEECCCCCCC
IEFVLELKAHNSVEVNRHQLLQILVNLQMNAIHAMNGKGRITIRSEDWVEEGQNRGAVIH
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEECCHHHHHCCCCCCEEEE
IEDQGCGIKPENLKRIFDPFYTTKREGTGLGLSVSQSLLSQSGGEIKVQSELGVGSTFSI
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEE
FLPSKNEAKLRETLLLQ
EECCCCHHHHHHHHCCC
>Mature Secondary Structure
MKAKWAWWQKWRHRFQTTVRYRLWILTSAPIFLTLLALIAITIYWSLHYTWNSALIDVSE
CCCCHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHEEEEECCHHEEHHH
RLGVAQNSVTLLQQKQANHVRAFAESYDFRKRLQEPETLSTLPRWVQNQKNRYGLDFLSF
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHH
ERVDSLEQKFRYLDLTKRESFFDVLSADELEKLDPDLAKQAQIPILNSQQIETRGLVSRT
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHC
VIPVRNDFGEIIGFLDGGLLLNNSTTLVDQIRDLIYPSHQDQLRPTGTLTLFLDDLRVST
EECCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECEEEEC
NVPLDSNIHAGRAIGTRVSSEVFNQVLKGGQQWVNLAYVYDAWYITAYEPIRDQYHNEIG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEEEEEEEEEEEEEHHHHHHHHCHHH
MLYTGYLMWPFLKAYVTNILEVGIITLFLLVISGLFVYRGSRDLFRPIERIHRVVKMVQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GKNQRIGQIGLDDKHELAQLAKQFDNMLDQLQQRNEEIVQAAHELEAKVQSRTASLQEKT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLEHHIALLNQTRNKLVVHEKLAALGELTAGIAHEINNPTAVILGNTELIRFELGADAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCHH
RVEEEIDAILLQIERIRNITRSLLQYSRQGGVQDEITWQHVNPIIDESITLVKTGSKKRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHCCCEEEEECCCCCCC
IEFVLELKAHNSVEVNRHQLLQILVNLQMNAIHAMNGKGRITIRSEDWVEEGQNRGAVIH
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEECCHHHHHCCCCCCEEEE
IEDQGCGIKPENLKRIFDPFYTTKREGTGLGLSVSQSLLSQSGGEIKVQSELGVGSTFSI
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEE
FLPSKNEAKLRETLLLQ
EECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]