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The map label for this gene is ybiT [H]

Identifier: 227081678

GI number: 227081678

Start: 1580692

End: 1582284

Strand: Reverse

Name: ybiT [H]

Synonym: VCM66_1462

Alternate gene names: 227081678

Gene position: 1582284-1580692 (Counterclockwise)

Preceding gene: 227081679

Following gene: 227081676

Centisome position: 54.7

GC content: 48.84

Gene sequence:

>1593_bases
TTGATTTCTACAGCGAATATCACTCAACAATTTGGCGCTAAGCCACTGTTTGAAAACATTTCAGTTAAGTTTGGCGAAGG
TAATCGCTACGGTCTAATCGGGGCAAATGGCTGTGGTAAATCCACCTTCATGAAAATCCTCAGTGGTGAGCTCGAACCAA
GTGGCGGTAATGTGAGCTACGATCCAAACGAGCGCGTTGCCAAGCTGAATCAGGATCAGTTTGCGTACGAAGAGTTCACG
GTAATCGACACCGTTATCATGGGTCACAAAGAGTTGTGGAAGGTAAAACAAGAGCGTGACCGTATTTATGCGCTGCCCGA
AATGACCGAAGAAGATGGTATGCGTGTTGCCGATCTCGAAGTGGAATTCGCCGAGATGGATGGCTACATGGCAGAATCCA
AAGCGGGTGAACTACTTCTCGCGGTGGGTATTCCTCTTGAGCAACATTACGGCCTGATGAGCAGTGTGGCTCCGGGTTGG
AAACTGCGTGTGCTGCTGGCGCAAATCCTGTTTGCAGATCCAGATATCATGCTGCTTGACGAACCGACCAACAACTTGGA
CATCGACACCATTCGCTGGTTGGAAGATACGCTGAATGCGCGTAACTGCACCATGATCATCATCTCGCATGACCGCCACT
TCTTAAACTCAGTCTGTACCCACATGGCTGACTTGGATTACGGTGAGCTGCGTATTTACCCAGGCAACTACGACGAATAC
ATGACTGCGGCCACTCAAGCGCGTGAGCGTCTGTTATCTGATAACGCGAAGAAGAAAGCGCAAATTGCTGAACTGCAAAC
CTTCGTAGCGCGCTTCTCGGCGAACGCATCGAAAGCAAAACAAGCGACTTCTCGTGCAAGACAGATTGATAAGATCAAAC
TGGATGAAGTGAAGGCATCAAGCCGTCAGAACCCATTCATTCGTTTCGAGCAATCGAAAGAGCTATTCCGTAACGCCCTT
ATTGTTGAAAACCTCAGCCAAGGTTTTGATCATGACCTGTTCAGCAACTTCAACGCGATTTTTGAAGTGGGTGAGCGTGT
TGCCATCATCGGTGAGAACGGTGTGGGTAAAACCACATTGCTGAATACCCTAGCTGGCGTACTTGAGCCACGTAGCGGTA
TGTACAAGTGGTCTGAAAACTCGAATATTGGTTACTATGCGCAAGACCACGCTCACGAGTTCGCAGAAGATCTGAACCTG
ATGGAGTGGATGGGTCAGTGGCGTCAAGAAGGCGATGATGAGCAAGTGGTTCGCAGCTTCTTGGGCCGTATGCTGTTTGG
CCAAGATGACATCAAGAAATCCGTGAAGGTACTGTCGGGTGGTGAGCAAGGTCGTATGTTGCTTGGCAAACTCATGATGC
ACAAGCCAAACATGCTGCTGCTCGATGAGCCAACCAACCACATGGATATGGAATCGATCGAGTCTTTGAACAACGCCTTA
GAGCAATATAAAGGCACGCTGTTCTTCGTATCGCATGACCGCGTATTCGTAGACTCTTTGGCGACTCGCATCATCGAAAT
TCGTGATGGCAAAATCACTGACTTCAAAGGCACTTACGCTGAGTTCCTGAAATCACGTGGCGTTGAAGGCTAA

Upstream 100 bases:

>100_bases
GCGCAGATTTTTCTATTTGTGATCCCTGTCAGCTTAATTTAGCCACTCGAAGTGCGCCGTTTTAAGTGGGCGGGAATGTT
AACGCACTAAGGTACAGGCT

Downstream 100 bases:

>100_bases
GTTTCCTAAGCCAATATTTTGCATGCTAAATAATACTAAGAGCCTCTATGTGAGGCTCTTTTGCTATCCGAAACACGTTA
AAAACCTCTATGGTGCAAAG

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MISTANITQQFGAKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILSGELEPSGGNVSYDPNERVAKLNQDQFAYEEFT
VIDTVIMGHKELWKVKQERDRIYALPEMTEEDGMRVADLEVEFAEMDGYMAESKAGELLLAVGIPLEQHYGLMSSVAPGW
KLRVLLAQILFADPDIMLLDEPTNNLDIDTIRWLEDTLNARNCTMIIISHDRHFLNSVCTHMADLDYGELRIYPGNYDEY
MTAATQARERLLSDNAKKKAQIAELQTFVARFSANASKAKQATSRARQIDKIKLDEVKASSRQNPFIRFEQSKELFRNAL
IVENLSQGFDHDLFSNFNAIFEVGERVAIIGENGVGKTTLLNTLAGVLEPRSGMYKWSENSNIGYYAQDHAHEFAEDLNL
MEWMGQWRQEGDDEQVVRSFLGRMLFGQDDIKKSVKVLSGGEQGRMLLGKLMMHKPNMLLLDEPTNHMDMESIESLNNAL
EQYKGTLFFVSHDRVFVDSLATRIIEIRDGKITDFKGTYAEFLKSRGVEG

Sequences:

>Translated_530_residues
MISTANITQQFGAKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILSGELEPSGGNVSYDPNERVAKLNQDQFAYEEFT
VIDTVIMGHKELWKVKQERDRIYALPEMTEEDGMRVADLEVEFAEMDGYMAESKAGELLLAVGIPLEQHYGLMSSVAPGW
KLRVLLAQILFADPDIMLLDEPTNNLDIDTIRWLEDTLNARNCTMIIISHDRHFLNSVCTHMADLDYGELRIYPGNYDEY
MTAATQARERLLSDNAKKKAQIAELQTFVARFSANASKAKQATSRARQIDKIKLDEVKASSRQNPFIRFEQSKELFRNAL
IVENLSQGFDHDLFSNFNAIFEVGERVAIIGENGVGKTTLLNTLAGVLEPRSGMYKWSENSNIGYYAQDHAHEFAEDLNL
MEWMGQWRQEGDDEQVVRSFLGRMLFGQDDIKKSVKVLSGGEQGRMLLGKLMMHKPNMLLLDEPTNHMDMESIESLNNAL
EQYKGTLFFVSHDRVFVDSLATRIIEIRDGKITDFKGTYAEFLKSRGVEG
>Mature_530_residues
MISTANITQQFGAKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILSGELEPSGGNVSYDPNERVAKLNQDQFAYEEFT
VIDTVIMGHKELWKVKQERDRIYALPEMTEEDGMRVADLEVEFAEMDGYMAESKAGELLLAVGIPLEQHYGLMSSVAPGW
KLRVLLAQILFADPDIMLLDEPTNNLDIDTIRWLEDTLNARNCTMIIISHDRHFLNSVCTHMADLDYGELRIYPGNYDEY
MTAATQARERLLSDNAKKKAQIAELQTFVARFSANASKAKQATSRARQIDKIKLDEVKASSRQNPFIRFEQSKELFRNAL
IVENLSQGFDHDLFSNFNAIFEVGERVAIIGENGVGKTTLLNTLAGVLEPRSGMYKWSENSNIGYYAQDHAHEFAEDLNL
MEWMGQWRQEGDDEQVVRSFLGRMLFGQDDIKKSVKVLSGGEQGRMLLGKLMMHKPNMLLLDEPTNHMDMESIESLNNAL
EQYKGTLFFVSHDRVFVDSLATRIIEIRDGKITDFKGTYAEFLKSRGVEG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=528, Percent_Identity=29.3560606060606, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI10947137, Length=541, Percent_Identity=29.7597042513863, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI27881506, Length=541, Percent_Identity=29.7597042513863, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI69354671, Length=528, Percent_Identity=29.1666666666667, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI10947135, Length=528, Percent_Identity=29.1666666666667, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI255708477, Length=220, Percent_Identity=25.9090909090909, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787041, Length=530, Percent_Identity=77.3584905660377, Blast_Score=872, Evalue=0.0,
Organism=Escherichia coli, GI1789751, Length=528, Percent_Identity=31.8181818181818, Blast_Score=281, Evalue=5e-77,
Organism=Escherichia coli, GI1787182, Length=536, Percent_Identity=32.8358208955224, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI2367384, Length=524, Percent_Identity=30.3435114503817, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787029, Length=234, Percent_Identity=27.3504273504274, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786398, Length=238, Percent_Identity=28.1512605042017, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786803, Length=233, Percent_Identity=28.3261802575107, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788165, Length=177, Percent_Identity=28.2485875706215, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789672, Length=257, Percent_Identity=26.0700389105058, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=256, Percent_Identity=24.21875, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787164, Length=221, Percent_Identity=27.1493212669683, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790525, Length=228, Percent_Identity=25.4385964912281, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994943, Length=244, Percent_Identity=26.6393442622951, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786698, Length=182, Percent_Identity=27.4725274725275, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081834, Length=202, Percent_Identity=28.2178217821782, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=531, Percent_Identity=29.7551789077213, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17553372, Length=520, Percent_Identity=29.0384615384615, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17559834, Length=537, Percent_Identity=27.7467411545624, Blast_Score=203, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320874, Length=532, Percent_Identity=30.4511278195489, Blast_Score=247, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6321121, Length=532, Percent_Identity=28.7593984962406, Blast_Score=229, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6323278, Length=415, Percent_Identity=28.1927710843373, Blast_Score=130, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6325030, Length=428, Percent_Identity=26.4018691588785, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=417, Percent_Identity=26.8585131894484, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24642252, Length=541, Percent_Identity=29.7597042513863, Blast_Score=246, Evalue=4e-65,
Organism=Drosophila melanogaster, GI18859989, Length=541, Percent_Identity=29.7597042513863, Blast_Score=246, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24666836, Length=513, Percent_Identity=31.3840155945419, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24641342, Length=540, Percent_Identity=29.0740740740741, Blast_Score=225, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59950; Mature: 59950

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTANITQQFGAKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILSGELEPSGGNVSY
CCCCCCHHHHHCCCCCHHCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
DPNERVAKLNQDQFAYEEFTVIDTVIMGHKELWKVKQERDRIYALPEMTEEDGMRVADLE
CCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEECCCCCCCCCCEEEEEE
VEFAEMDGYMAESKAGELLLAVGIPLEQHYGLMSSVAPGWKLRVLLAQILFADPDIMLLD
EEEHHHCCCHHHCCCCCEEEEECCCHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCEEEEE
EPTNNLDIDTIRWLEDTLNARNCTMIIISHDRHFLNSVCTHMADLDYGELRIYPGNYDEY
CCCCCCCCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCHHHH
MTAATQARERLLSDNAKKKAQIAELQTFVARFSANASKAKQATSRARQIDKIKLDEVKAS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHC
SRQNPFIRFEQSKELFRNALIVENLSQGFDHDLFSNFNAIFEVGERVAIIGENGVGKTTL
CCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
LNTLAGVLEPRSGMYKWSENSNIGYYAQDHAHEFAEDLNLMEWMGQWRQEGDDEQVVRSF
HHHHHHHHCCCCCCEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGRMLFGQDDIKKSVKVLSGGEQGRMLLGKLMMHKPNMLLLDEPTNHMDMESIESLNNAL
HHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
EQYKGTLFFVSHDRVFVDSLATRIIEIRDGKITDFKGTYAEFLKSRGVEG
HHHCCEEEEEECCHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MISTANITQQFGAKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILSGELEPSGGNVSY
CCCCCCHHHHHCCCCCHHCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
DPNERVAKLNQDQFAYEEFTVIDTVIMGHKELWKVKQERDRIYALPEMTEEDGMRVADLE
CCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEECCCCCCCCCCEEEEEE
VEFAEMDGYMAESKAGELLLAVGIPLEQHYGLMSSVAPGWKLRVLLAQILFADPDIMLLD
EEEHHHCCCHHHCCCCCEEEEECCCHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCEEEEE
EPTNNLDIDTIRWLEDTLNARNCTMIIISHDRHFLNSVCTHMADLDYGELRIYPGNYDEY
CCCCCCCCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCHHHH
MTAATQARERLLSDNAKKKAQIAELQTFVARFSANASKAKQATSRARQIDKIKLDEVKAS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHC
SRQNPFIRFEQSKELFRNALIVENLSQGFDHDLFSNFNAIFEVGERVAIIGENGVGKTTL
CCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
LNTLAGVLEPRSGMYKWSENSNIGYYAQDHAHEFAEDLNLMEWMGQWRQEGDDEQVVRSF
HHHHHHHHCCCCCCEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGRMLFGQDDIKKSVKVLSGGEQGRMLLGKLMMHKPNMLLLDEPTNHMDMESIESLNNAL
HHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
EQYKGTLFFVSHDRVFVDSLATRIIEIRDGKITDFKGTYAEFLKSRGVEG
HHHCCEEEEEECCHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]