Click here to switch to the map view.

The map label for this gene is bdlA [H]

Identifier: 227081577

GI number: 227081577

Start: 1455610

End: 1456926

Strand: Direct

Name: bdlA [H]

Synonym: VCM66_1361

Alternate gene names: 227081577

Gene position: 1455610-1456926 (Clockwise)

Preceding gene: 227081576

Following gene: 227081578

Centisome position: 50.32

GC content: 44.5

Gene sequence:

>1317_bases
TTGATTTGGAAGCCATTTATGCCATTTTGGAAAAAAGCTGCCGCCCAATCAGAGGTGGAACAACACAATCATGACAGCGA
CATTGTCTCTGCACTTAAAAGGAACCTTGCGTATATCGAGTTTGATCCGCAAGGCAAAATTTTAGATGCAAACGCACTTT
TTTTGAGCGCAATGGGGTACACCAAAGAAGAAGTGATTGGTCAACATCACAAAATTTTTTGTGATCCCGAGACTGTTAAC
TCCTTGGAATATGCACAATTTTGGAAAAGCCTAGCCCAAGGACAAGCGCAACGAAAAATGTTTCACCGACTCAAGAAAGA
TGGTTCGAGTATCTGGATAGAGGCAACGTATATGCCAGTACGTAATCGTGCGGGCGATGTATATAAGGTGATCAAAGTTG
CCCATGATGTGACGAAAGCCAAAATTACGGCGGACAAGCAGGCTGCGGTATTTCATTCTCTGGATCGTTCATCAGCCATG
ATTCAGTTTAATCCGGATGGAACCATCAAAGAGGCGAATGAGAACTTTCTCAAAGCCACGGGTTATCGACTGGAAGAGAT
TGTTGGCAAACATCACCGTATGTTTTGTGATGACCGTTTCTATAAAGAAAATCCAAACTTTTGGCGTGAGCTCGCAAGAG
GGGAGTTTAAATCCGGTTTATTCCATCGGCGCACTCGTCACGGTCAAGATCTTTGGTTAGAGGCGACGTATAACCCGATT
TTTAATGATGCAGGTGTCGTGACTCAAGTTGTTAAATTTGCTTCAGATGTTACAGATCAAGTGTTAAAAGCTCATGCAAC
CAAAGAAGCGTCGCAAATGGCTCAGCAAACGTCTGCAGAAACGGTTCGTGTGGCAGAGTCGGGGCGCGAGATGATTGATG
CTGCGGCAACGATAGCGAGTGGTATTACAGAGTCAATTGCGGGTGCAAATGCATTGATGACGGACCTCTCATCTCAATCT
CAGAGAATCACGCAAATAGTCACAACCATCAACAAAATTGCTGAGCAGACCAATTTGTTAGCTTTAAATGCCGCCATTGA
GGCCGCTCGAGCAGGTGAATATGGACGTGGCTTTGCTGTAGTGGCTGATGAGGTGCGCAGTTTAGCGTCGAATACCAGTC
AAGCAACTAGCGAAATTGACAACATTGTTAAACGCAACAGCCAACTCACCGAACAGTCAGGGCAAACCATGGAGCAGATC
CAAGCCAAAGTCACTGAATTCAATCATATGCTGCAACAAACCCAGTCTTTGATTGAGCAAATTCAGCATGCAGCGGAAAA
TGTACAAAAAACGGTGAGTAATATTGTGGATGAATAA

Upstream 100 bases:

>100_bases
GGGACGCTTTGTTATTTCGTAACAGTGTGTTGTCACTAAACGAGTAGAGTATTACAAACATAAAAGATAAGGCTCTCTAC
TATAATGAGTTTGAGAGTCA

Downstream 100 bases:

>100_bases
GATGAGCCGGAAAGCCATCCAGTAGTAAGCCTAAACCATGGCTTCATTCATCATCTCATGTTGAAACAATAGCGTTGTAA
GAAGAAAAAACACAGCGGTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MIWKPFMPFWKKAAAQSEVEQHNHDSDIVSALKRNLAYIEFDPQGKILDANALFLSAMGYTKEEVIGQHHKIFCDPETVN
SLEYAQFWKSLAQGQAQRKMFHRLKKDGSSIWIEATYMPVRNRAGDVYKVIKVAHDVTKAKITADKQAAVFHSLDRSSAM
IQFNPDGTIKEANENFLKATGYRLEEIVGKHHRMFCDDRFYKENPNFWRELARGEFKSGLFHRRTRHGQDLWLEATYNPI
FNDAGVVTQVVKFASDVTDQVLKAHATKEASQMAQQTSAETVRVAESGREMIDAAATIASGITESIAGANALMTDLSSQS
QRITQIVTTINKIAEQTNLLALNAAIEAARAGEYGRGFAVVADEVRSLASNTSQATSEIDNIVKRNSQLTEQSGQTMEQI
QAKVTEFNHMLQQTQSLIEQIQHAAENVQKTVSNIVDE

Sequences:

>Translated_438_residues
MIWKPFMPFWKKAAAQSEVEQHNHDSDIVSALKRNLAYIEFDPQGKILDANALFLSAMGYTKEEVIGQHHKIFCDPETVN
SLEYAQFWKSLAQGQAQRKMFHRLKKDGSSIWIEATYMPVRNRAGDVYKVIKVAHDVTKAKITADKQAAVFHSLDRSSAM
IQFNPDGTIKEANENFLKATGYRLEEIVGKHHRMFCDDRFYKENPNFWRELARGEFKSGLFHRRTRHGQDLWLEATYNPI
FNDAGVVTQVVKFASDVTDQVLKAHATKEASQMAQQTSAETVRVAESGREMIDAAATIASGITESIAGANALMTDLSSQS
QRITQIVTTINKIAEQTNLLALNAAIEAARAGEYGRGFAVVADEVRSLASNTSQATSEIDNIVKRNSQLTEQSGQTMEQI
QAKVTEFNHMLQQTQSLIEQIQHAAENVQKTVSNIVDE
>Mature_438_residues
MIWKPFMPFWKKAAAQSEVEQHNHDSDIVSALKRNLAYIEFDPQGKILDANALFLSAMGYTKEEVIGQHHKIFCDPETVN
SLEYAQFWKSLAQGQAQRKMFHRLKKDGSSIWIEATYMPVRNRAGDVYKVIKVAHDVTKAKITADKQAAVFHSLDRSSAM
IQFNPDGTIKEANENFLKATGYRLEEIVGKHHRMFCDDRFYKENPNFWRELARGEFKSGLFHRRTRHGQDLWLEATYNPI
FNDAGVVTQVVKFASDVTDQVLKAHATKEASQMAQQTSAETVRVAESGREMIDAAATIASGITESIAGANALMTDLSSQS
QRITQIVTTINKIAEQTNLLALNAAIEAARAGEYGRGFAVVADEVRSLASNTSQATSEIDNIVKRNSQLTEQSGQTMEQI
QAKVTEFNHMLQQTQSLIEQIQHAAENVQKTVSNIVDE

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=158, Percent_Identity=41.1392405063291, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787690, Length=117, Percent_Identity=44.4444444444444, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI2367378, Length=111, Percent_Identity=47.7477477477478, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789453, Length=116, Percent_Identity=47.4137931034483, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788195, Length=175, Percent_Identity=37.1428571428571, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 49101; Mature: 49101

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWKPFMPFWKKAAAQSEVEQHNHDSDIVSALKRNLAYIEFDPQGKILDANALFLSAMGY
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCEEECHHHHHHHCCC
TKEEVIGQHHKIFCDPETVNSLEYAQFWKSLAQGQAQRKMFHRLKKDGSSIWIEATYMPV
CHHHHCCCCCEEEECHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEEECCH
RNRAGDVYKVIKVAHDVTKAKITADKQAAVFHSLDRSSAMIQFNPDGTIKEANENFLKAT
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCHHCHHHHHHC
GYRLEEIVGKHHRMFCDDRFYKENPNFWRELARGEFKSGLFHRRTRHGQDLWLEATYNPI
CCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
FNDAGVVTQVVKFASDVTDQVLKAHATKEASQMAQQTSAETVRVAESGREMIDAAATIAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITESIAGANALMTDLSSQSQRITQIVTTINKIAEQTNLLALNAAIEAARAGEYGRGFAV
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VADEVRSLASNTSQATSEIDNIVKRNSQLTEQSGQTMEQIQAKVTEFNHMLQQTQSLIEQ
HHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IQHAAENVQKTVSNIVDE
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIWKPFMPFWKKAAAQSEVEQHNHDSDIVSALKRNLAYIEFDPQGKILDANALFLSAMGY
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCEEECHHHHHHHCCC
TKEEVIGQHHKIFCDPETVNSLEYAQFWKSLAQGQAQRKMFHRLKKDGSSIWIEATYMPV
CHHHHCCCCCEEEECHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEEECCH
RNRAGDVYKVIKVAHDVTKAKITADKQAAVFHSLDRSSAMIQFNPDGTIKEANENFLKAT
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCHHCHHHHHHC
GYRLEEIVGKHHRMFCDDRFYKENPNFWRELARGEFKSGLFHRRTRHGQDLWLEATYNPI
CCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
FNDAGVVTQVVKFASDVTDQVLKAHATKEASQMAQQTSAETVRVAESGREMIDAAATIAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITESIAGANALMTDLSSQSQRITQIVTTINKIAEQTNLLALNAAIEAARAGEYGRGFAV
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VADEVRSLASNTSQATSEIDNIVKRNSQLTEQSGQTMEQIQAKVTEFNHMLQQTQSLIEQ
HHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IQHAAENVQKTVSNIVDE
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]