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The map label for this gene is msmR [H]

Identifier: 227081432

GI number: 227081432

Start: 1291568

End: 1292467

Strand: Reverse

Name: msmR [H]

Synonym: VCM66_1215

Alternate gene names: 227081432

Gene position: 1292467-1291568 (Counterclockwise)

Preceding gene: 227081443

Following gene: 227081429

Centisome position: 44.68

GC content: 47.11

Gene sequence:

>900_bases
ATGCGACCTTTAATTGAAAATGTGATGAGCGGTATTAGTCAGGATTGGGTGCTGCGTGAATTTCGCAGCAAGAGCCAAAC
TCAAGAATTTTCCTGTCCTTGGCACTACCACACCGAATATGAATTAGTGCTCTACCAGAACCCTGATCAGCGTTTTGTCG
GTAACTATTTTGCAGGGGATGCGATTGGCGCGGTTGAGCACAACACACTTTTACTTTACGGCCCCGGTTTACCACATATG
ATTGCGGGTAGACAGCTGATCAATAAAGCCCAAACTCTGCACTCAACGATTATCTGGTTCAAACAAGAGTGGCTAGATAA
GCTACAGAGCGTATTGCCTCAAGCTCAAGCTTTGCAACGCTTGCAGCAACATGCCTCCTATGGCGTGCGTCTCAGTGAGC
AAACCGCTACGCGCGTCGCCGAACTCCTAGCCAATGTTGATCAACAGCCTCACAGTTACCAATCTCTGCGCGTGATTGAG
TCCTTGCTTGTGATGGCGGACGATGCGCAGGCACAGCGTCTATCTGTCGCACCCTATGTGATGACGGCACTCACCAGCAA
CAGTGACACGCATAAGAAAATTCAACTGGCCAAACAATATGTGGAGCAGCACTACGCACAAGCAATAAAAATTACCGACT
TATGTCATCAGTTACATTTGAGCGAAAGCTCGGCGTATCGCTTATTTGAAAAGCACTATGGGATGAGTTTTTCTGAGCAT
TTAAAGCAGTTTCGAATTGGTAAAGCGTGTGAGCTTTTAGCCAGTTCTGCGCTGCCGATTGCATTAATTGCCGAGCGAAC
TGGGTTTGGCAATTTGTCGAACTTTAACCGCCAATTTAAAACCCTCAAAACCATGACTCCGAGAGAGTTTCGCCAACGAT
TTCAAGCAGTAAGTGGGTAG

Upstream 100 bases:

>100_bases
ATACTATTCAGGCAAAATCACTTGATGATTTGACAGAAAATAAGCCATTCCTCTAGTCTATCTCCATGCATTGAGCGCAT
GAAAACTCACGTAAATCGTT

Downstream 100 bases:

>100_bases
CAAAACGGCCACCCACTCACGACTCGTTAGCCTTTCTGGCCGCGCTGCGCCGCTTTGCGCGCCAGCTTTTCTGCGCGGCG
TTTTTCAATCAGTGCCGCAC

Product: transcriptional regulator, AraC/XylS family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MRPLIENVMSGISQDWVLREFRSKSQTQEFSCPWHYHTEYELVLYQNPDQRFVGNYFAGDAIGAVEHNTLLLYGPGLPHM
IAGRQLINKAQTLHSTIIWFKQEWLDKLQSVLPQAQALQRLQQHASYGVRLSEQTATRVAELLANVDQQPHSYQSLRVIE
SLLVMADDAQAQRLSVAPYVMTALTSNSDTHKKIQLAKQYVEQHYAQAIKITDLCHQLHLSESSAYRLFEKHYGMSFSEH
LKQFRIGKACELLASSALPIALIAERTGFGNLSNFNRQFKTLKTMTPREFRQRFQAVSG

Sequences:

>Translated_299_residues
MRPLIENVMSGISQDWVLREFRSKSQTQEFSCPWHYHTEYELVLYQNPDQRFVGNYFAGDAIGAVEHNTLLLYGPGLPHM
IAGRQLINKAQTLHSTIIWFKQEWLDKLQSVLPQAQALQRLQQHASYGVRLSEQTATRVAELLANVDQQPHSYQSLRVIE
SLLVMADDAQAQRLSVAPYVMTALTSNSDTHKKIQLAKQYVEQHYAQAIKITDLCHQLHLSESSAYRLFEKHYGMSFSEH
LKQFRIGKACELLASSALPIALIAERTGFGNLSNFNRQFKTLKTMTPREFRQRFQAVSG
>Mature_299_residues
MRPLIENVMSGISQDWVLREFRSKSQTQEFSCPWHYHTEYELVLYQNPDQRFVGNYFAGDAIGAVEHNTLLLYGPGLPHM
IAGRQLINKAQTLHSTIIWFKQEWLDKLQSVLPQAQALQRLQQHASYGVRLSEQTATRVAELLANVDQQPHSYQSLRVIE
SLLVMADDAQAQRLSVAPYVMTALTSNSDTHKKIQLAKQYVEQHYAQAIKITDLCHQLHLSESSAYRLFEKHYGMSFSEH
LKQFRIGKACELLASSALPIALIAERTGFGNLSNFNRQFKTLKTMTPREFRQRFQAVSG

Specific function: Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34254; Mature: 34254

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLIENVMSGISQDWVLREFRSKSQTQEFSCPWHYHTEYELVLYQNPDQRFVGNYFAGD
CCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCHHHHCCHHCCC
AIGAVEHNTLLLYGPGLPHMIAGRQLINKAQTLHSTIIWFKQEWLDKLQSVLPQAQALQR
CCCCEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LQQHASYGVRLSEQTATRVAELLANVDQQPHSYQSLRVIESLLVMADDAQAQRLSVAPYV
HHHHHHHCCEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MTALTSNSDTHKKIQLAKQYVEQHYAQAIKITDLCHQLHLSESSAYRLFEKHYGMSFSEH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
LKQFRIGKACELLASSALPIALIAERTGFGNLSNFNRQFKTLKTMTPREFRQRFQAVSG
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRPLIENVMSGISQDWVLREFRSKSQTQEFSCPWHYHTEYELVLYQNPDQRFVGNYFAGD
CCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCHHHHCCHHCCC
AIGAVEHNTLLLYGPGLPHMIAGRQLINKAQTLHSTIIWFKQEWLDKLQSVLPQAQALQR
CCCCEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LQQHASYGVRLSEQTATRVAELLANVDQQPHSYQSLRVIESLLVMADDAQAQRLSVAPYV
HHHHHHHCCEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MTALTSNSDTHKKIQLAKQYVEQHYAQAIKITDLCHQLHLSESSAYRLFEKHYGMSFSEH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
LKQFRIGKACELLASSALPIALIAERTGFGNLSNFNRQFKTLKTMTPREFRQRFQAVSG
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537846; 12397186 [H]