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The map label for this gene is ubiG

Identifier: 227081429

GI number: 227081429

Start: 1286557

End: 1287294

Strand: Reverse

Name: ubiG

Synonym: VCM66_1212

Alternate gene names: 227081429

Gene position: 1287294-1286557 (Counterclockwise)

Preceding gene: 227081432

Following gene: 227081428

Centisome position: 44.5

GC content: 48.78

Gene sequence:

>738_bases
ATGGCTTCAATAGACTTGGCTTCGACACCACTGACAGCAACACAGAACGTCGATCCTAATGAAATCAAAAAATTTGAGGA
TATGGCTTCCCGTTGGTGGGATCTGGAAGGCGAATTTAAGCCTTTACACCAGATCAACCCTCTACGTTTGAACTATGTGC
TAGAAAAAGCCAATGGCCTGTTTGGGAAGAGGGTTTTGGATGTCGGCTGTGGTGGCGGCATTTTAGCCGAAAGCATGGCG
CGCGAAGGCGCACAAGTGACTGGTCTTGATATGGGGAAAGAGCCGCTTGAAGTAGCACGTTTACATGCCCTTGAGACGGG
TACCAAACTCACCTACATCCAAAGCACGGTGGAAGCACATGCTGAGGCCAACCCGCACACCTATGATGTAGTGACTTGCA
TGGAGATGCTGGAGCACGTTCCTGACCCACTTTCCGTGATCCAGTCTTGCGCCAAACTGGTTAAGCCCGGCGGCCATGTG
TTTTTCTCGACCCTGAATCGCAACGTCAAATCCTATCTATTTGCGATTGTGGGGGCTGAGAAGCTGCTGAAAATCGTTCC
AGAAGGCACGCATGACCACAACAAATTCATTCGCCCTTCTGAGCTTTTGAAGATGGTTGATCATACTGCGCTGCAAGAAC
AAGGCATCACAGGTTTACACTACAATCCGTTTACCGATACCTATCGTTTAGGGTCGAATGTCGATGTGAATTACATCGTC
CATACTCGCCTTTTTTAG

Upstream 100 bases:

>100_bases
TTTAAACGCTCATCGTCAAATCTGGCATCTCAACTGGTGCGATTTACTCAGCGCGCTATAATGCCCACTCTTCACGGATG
CGTAACACAGGCGATACAAG

Downstream 100 bases:

>100_bases
CGCATACTCCACGCTAAAAAATCGATGCGGTAGCACAAGTTACCGCGCTTTTTTAGCCTATTTTTCGTGCGTTTGATTCC
ATTTTAAACGATCCATTTTT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MASIDLASTPLTATQNVDPNEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKANGLFGKRVLDVGCGGGILAESMA
REGAQVTGLDMGKEPLEVARLHALETGTKLTYIQSTVEAHAEANPHTYDVVTCMEMLEHVPDPLSVIQSCAKLVKPGGHV
FFSTLNRNVKSYLFAIVGAEKLLKIVPEGTHDHNKFIRPSELLKMVDHTALQEQGITGLHYNPFTDTYRLGSNVDVNYIV
HTRLF

Sequences:

>Translated_245_residues
MASIDLASTPLTATQNVDPNEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKANGLFGKRVLDVGCGGGILAESMA
REGAQVTGLDMGKEPLEVARLHALETGTKLTYIQSTVEAHAEANPHTYDVVTCMEMLEHVPDPLSVIQSCAKLVKPGGHV
FFSTLNRNVKSYLFAIVGAEKLLKIVPEGTHDHNKFIRPSELLKMVDHTALQEQGITGLHYNPFTDTYRLGSNVDVNYIV
HTRLF
>Mature_244_residues
ASIDLASTPLTATQNVDPNEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKANGLFGKRVLDVGCGGGILAESMAR
EGAQVTGLDMGKEPLEVARLHALETGTKLTYIQSTVEAHAEANPHTYDVVTCMEMLEHVPDPLSVIQSCAKLVKPGGHVF
FSTLNRNVKSYLFAIVGAEKLLKIVPEGTHDHNKFIRPSELLKMVDHTALQEQGITGLHYNPFTDTYRLGSNVDVNYIVH
TRLF

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=243, Percent_Identity=34.156378600823, Blast_Score=168, Evalue=4e-42,
Organism=Escherichia coli, GI1788564, Length=230, Percent_Identity=70.8695652173913, Blast_Score=352, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI115533050, Length=234, Percent_Identity=33.7606837606838, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324476, Length=235, Percent_Identity=31.9148936170213, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281365311, Length=236, Percent_Identity=33.4745762711864, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24585589, Length=225, Percent_Identity=33.7777777777778, Blast_Score=151, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_VIBC3 (A5F1U0)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F1U0
- STRING:   A5F1U0
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0876
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- ProtClustDB:   PRK05134
- BioCyc:   VCHO345073:VC0395_A0876-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 27239; Mature: 27107

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIDLASTPLTATQNVDPNEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKANGL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCH
FGKRVLDVGCGGGILAESMAREGAQVTGLDMGKEPLEVARLHALETGTKLTYIQSTVEAH
HHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AEANPHTYDVVTCMEMLEHVPDPLSVIQSCAKLVKPGGHVFFSTLNRNVKSYLFAIVGAE
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHH
KLLKIVPEGTHDHNKFIRPSELLKMVDHTALQEQGITGLHYNPFTDTYRLGSNVDVNYIV
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCEEEEE
HTRLF
EEECC
>Mature Secondary Structure 
ASIDLASTPLTATQNVDPNEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKANGL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCH
FGKRVLDVGCGGGILAESMAREGAQVTGLDMGKEPLEVARLHALETGTKLTYIQSTVEAH
HHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AEANPHTYDVVTCMEMLEHVPDPLSVIQSCAKLVKPGGHVFFSTLNRNVKSYLFAIVGAE
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHH
KLLKIVPEGTHDHNKFIRPSELLKMVDHTALQEQGITGLHYNPFTDTYRLGSNVDVNYIV
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCEEEEE
HTRLF
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA