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The map label for this gene is cmoA

Identifier: 227081336

GI number: 227081336

Start: 1193536

End: 1194276

Strand: Reverse

Name: cmoA

Synonym: VCM66_1119

Alternate gene names: 227081336

Gene position: 1194276-1193536 (Counterclockwise)

Preceding gene: 227081337

Following gene: 227081335

Centisome position: 41.29

GC content: 49.66

Gene sequence:

>741_bases
ATGAGGTCTGCTATGAACCCAAAAGATACTCTCTTTTCCGCACCCATCGATAAAATCGGTGATTTCACCTTTGACGAGCG
CGTGGCTGAAGTTTTTCCAGACATGATCCAACGTTCGGTACCGGGTTACAGCAACATCATATCTGCGATTGGCATGCTGG
CTGAGCGCTTTGTAAAGCCTCATTCCAAGATTTACGACTTAGGCTGCTCACTGGGTGCGGCAACCCTTTCTATGCGCCGC
CATATCAAACAAGAAGGCTGCCAAATCATTGCTGTCGATAACTCAGCGGCCATGGTGGAACGCTGCAAGCTGCACCTCAA
CGCTTATCGCTCGGACACACCAGTGCAGGTGATCGAAGCGGATATTCGCGATATCGCGATTGAAAATGCCTCCGTCGTAG
TGCTCAACTTTACCTTGCAGTTTCTCGCGCCGGATGATCGCTACGCGCTGCTAGAAAAAATCTACGCCGGATTACGCCCG
GGTGGCATTTTGATCTTGTCGGAAAAATTTGTGTTTTCGGATCAAGAAGCCCACGAGCTGCTGATCGATTTGCACCACGA
TTTCAAACGTGCCAACGGATACAGCGAGCTGGAGATCAGCCAAAAACGCAGCGCGATTGAAAATGTGATGCGCCCAGATT
CCATCCAGACCCACAAACAGCGTTTTGCCACTCTCGGCTTTTCTAGCTTTGAAGTCTGGTTCCAGTGCTTTAACTTTGGC
TCTATGTTCGCCATTAAGTAA

Upstream 100 bases:

>100_bases
ACCCTAAAGGCGATGTGTTTAATGACAGACGCTGCGATTTTTCATAAAATACGCGCCTTTTATTGAGCCAGCGCCACAAA
AGCTGGCACAAGACGCTGCC

Downstream 100 bases:

>100_bases
ATCGCTTATTTTGTTAACTATTTTTGTCATTTATCTTCATGTTAGCGACTCTCTGCGCCACGTATGATCCTGAAGTCATG
TGCAGAGAGCATAGTTTAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRSAMNPKDTLFSAPIDKIGDFTFDERVAEVFPDMIQRSVPGYSNIISAIGMLAERFVKPHSKIYDLGCSLGAATLSMRR
HIKQEGCQIIAVDNSAAMVERCKLHLNAYRSDTPVQVIEADIRDIAIENASVVVLNFTLQFLAPDDRYALLEKIYAGLRP
GGILILSEKFVFSDQEAHELLIDLHHDFKRANGYSELEISQKRSAIENVMRPDSIQTHKQRFATLGFSSFEVWFQCFNFG
SMFAIK

Sequences:

>Translated_246_residues
MRSAMNPKDTLFSAPIDKIGDFTFDERVAEVFPDMIQRSVPGYSNIISAIGMLAERFVKPHSKIYDLGCSLGAATLSMRR
HIKQEGCQIIAVDNSAAMVERCKLHLNAYRSDTPVQVIEADIRDIAIENASVVVLNFTLQFLAPDDRYALLEKIYAGLRP
GGILILSEKFVFSDQEAHELLIDLHHDFKRANGYSELEISQKRSAIENVMRPDSIQTHKQRFATLGFSSFEVWFQCFNFG
SMFAIK
>Mature_246_residues
MRSAMNPKDTLFSAPIDKIGDFTFDERVAEVFPDMIQRSVPGYSNIISAIGMLAERFVKPHSKIYDLGCSLGAATLSMRR
HIKQEGCQIIAVDNSAAMVERCKLHLNAYRSDTPVQVIEADIRDIAIENASVVVLNFTLQFLAPDDRYALLEKIYAGLRP
GGILILSEKFVFSDQEAHELLIDLHHDFKRANGYSELEISQKRSAIENVMRPDSIQTHKQRFATLGFSSFEVWFQCFNFG
SMFAIK

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=242, Percent_Identity=71.4876033057851, Blast_Score=374, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_VIBC3 (A5F278)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F278
- SMR:   A5F278
- STRING:   A5F278
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0733
- eggNOG:   COG0500
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- ProtClustDB:   CLSK874240
- BioCyc:   VCHO345073:VC0395_A0733-MONOMER
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 27787; Mature: 27787

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: BINDING 43-43 BINDING 93-93 BINDING 136-136 BINDING 203-203

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAMNPKDTLFSAPIDKIGDFTFDERVAEVFPDMIQRSVPGYSNIISAIGMLAERFVKP
CCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCH
HSKIYDLGCSLGAATLSMRRHIKQEGCQIIAVDNSAAMVERCKLHLNAYRSDTPVQVIEA
HHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHH
DIRDIAIENASVVVLNFTLQFLAPDDRYALLEKIYAGLRPGGILILSEKFVFSDQEAHEL
HHHHHEECCCCEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCHHCCCHHHHHH
LIDLHHDFKRANGYSELEISQKRSAIENVMRPDSIQTHKQRFATLGFSSFEVWFQCFNFG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
SMFAIK
CEEEEC
>Mature Secondary Structure
MRSAMNPKDTLFSAPIDKIGDFTFDERVAEVFPDMIQRSVPGYSNIISAIGMLAERFVKP
CCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCH
HSKIYDLGCSLGAATLSMRRHIKQEGCQIIAVDNSAAMVERCKLHLNAYRSDTPVQVIEA
HHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHH
DIRDIAIENASVVVLNFTLQFLAPDDRYALLEKIYAGLRPGGILILSEKFVFSDQEAHEL
HHHHHEECCCCEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCHHCCCHHHHHH
LIDLHHDFKRANGYSELEISQKRSAIENVMRPDSIQTHKQRFATLGFSSFEVWFQCFNFG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
SMFAIK
CEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA