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The map label for this gene is gsk-1 [H]

Identifier: 227081302

GI number: 227081302

Start: 1154253

End: 1155557

Strand: Direct

Name: gsk-1 [H]

Synonym: VCM66_1085

Alternate gene names: 227081302

Gene position: 1154253-1155557 (Clockwise)

Preceding gene: 227081298

Following gene: 227081304

Centisome position: 39.9

GC content: 42.91

Gene sequence:

>1305_bases
ATGAAATTTCCTGGCCAACGCAAATCTAAGCATTATTTTCCGGTTCACGCGCGTGATCCTCTGGTCATTCAAGCGCAAGA
AAATAAGAAGATGTCGCGCACCCACATTATCGGTATTGATCAAACCCTAGTGGATATTGAGGCCAAAGTCGATTCAGATT
TGATTGAACGTTATGGTTTAAGTAAAGGACACTCATTGGTCATTGATGATCATGCTGCAGAAGCGTTATACAACGAATTA
AAAGAGCAGCGTTTGATTACCAATGAATATGCAGGTGGAACCATAGGGAATACGCTGCATAATTACTCCGTGCTTGCGGA
TGATCGCTCCACGCTACTGGGTGTGATGAGCCAAGATATTAAAATTGGCAGTTACGGTTATCGCTATCTGTGTAACACTT
CTAGCCGCATGGATCTCAACTATCTGCAAGGTGTAGATGGCGCGATTGGCCGCTGCTTTGCCTTAATTACCGAAGATGGT
GAACGTACTTTCGCGATCAGCGAAGGTCAAATGAACCAATTACGCCCAGACAGTATTCCTGAAAAAATATTTGCTAGTGC
CTCTGCATTAGTGATCACGGCTTATTTAGTTCGTTGTAAAGAAGGCGATCCAATGCCGGAAGCAACAATGCGTGCCATTG
AATATGCCAAAAAATATGATGTGCCTGTGGTATTAACCCTAGGTACTAAATTTGTTATTCAAGATGATCCGAAATTCTGG
CAAGAATTTTTACGTGATCATGTCACTGTGGTGGCAATGAATGAAGATGAAGCATTAGCTTTAACAGGAGAAAGCGATCC
GCTCGCAGCCTCAGATAAAGCGTTAGATTGGGTTGATTTAGTACTGTGTACTGCAGGCCCAGTCGGTTTATTTATGGCGG
GTTACACCGAAGATTCCGCTAAACGTGAAACGTCATTACCGTTATTACCGGGATCGGTCCCAGAATTTAACCGCTATGAA
TTTAGCCGCCCTGCCCGTAAAGAGAGTTGTATAAATCCTATTCGTGTTTATTCACATATTTCACCGTATATGGGCGGTCC
AGAGAAGATAAAAAATACCAATGGTGCTGGAGACGCAGCATTATCCGCTCTACTGCATGATATGGCGGCTAATAAATACC
ATAAAGAAAACGTCCCTAACTCAAGTAAGCATCAACATGAGTTTTTAACCTATTCTTCTTTCTCTCAAGTTTGCAAATAC
TCTAACCGTGCAAGTTATGAAGTATTGGCGCAGCACTCACCACGTCTTTCACGTGGTCTTCCTGAGCGAGAAGATAGCCT
TGAAGAGGCTTATTGGGAAAGATAA

Upstream 100 bases:

>100_bases
CCTCAGCGTGCAAACGTTTGCTTTTTTTTCCTTTATTGCTGCACTAAAAGGTGCGCGGTAGAATCGGCGCTCCTTTCATC
CTTGAACCCAAGTAACCTTT

Downstream 100 bases:

>100_bases
CAAAAAGGCTCCTTCGGGAGCCTTTATCATTTTAGTTTCTGGCAAAATTACAGAGCGAATTCTTCCAGAGATTTACCTTC
ATCCAGTGCTTTTTGGATCA

Product: inosine-guanosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFPGQRKSKHYFPVHARDPLVIQAQENKKMSRTHIIGIDQTLVDIEAKVDSDLIERYGLSKGHSLVIDDHAAEALYNEL
KEQRLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDIKIGSYGYRYLCNTSSRMDLNYLQGVDGAIGRCFALITEDG
ERTFAISEGQMNQLRPDSIPEKIFASASALVITAYLVRCKEGDPMPEATMRAIEYAKKYDVPVVLTLGTKFVIQDDPKFW
QEFLRDHVTVVAMNEDEALALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDSAKRETSLPLLPGSVPEFNRYE
FSRPARKESCINPIRVYSHISPYMGGPEKIKNTNGAGDAALSALLHDMAANKYHKENVPNSSKHQHEFLTYSSFSQVCKY
SNRASYEVLAQHSPRLSRGLPEREDSLEEAYWER

Sequences:

>Translated_434_residues
MKFPGQRKSKHYFPVHARDPLVIQAQENKKMSRTHIIGIDQTLVDIEAKVDSDLIERYGLSKGHSLVIDDHAAEALYNEL
KEQRLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDIKIGSYGYRYLCNTSSRMDLNYLQGVDGAIGRCFALITEDG
ERTFAISEGQMNQLRPDSIPEKIFASASALVITAYLVRCKEGDPMPEATMRAIEYAKKYDVPVVLTLGTKFVIQDDPKFW
QEFLRDHVTVVAMNEDEALALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDSAKRETSLPLLPGSVPEFNRYE
FSRPARKESCINPIRVYSHISPYMGGPEKIKNTNGAGDAALSALLHDMAANKYHKENVPNSSKHQHEFLTYSSFSQVCKY
SNRASYEVLAQHSPRLSRGLPEREDSLEEAYWER
>Mature_434_residues
MKFPGQRKSKHYFPVHARDPLVIQAQENKKMSRTHIIGIDQTLVDIEAKVDSDLIERYGLSKGHSLVIDDHAAEALYNEL
KEQRLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDIKIGSYGYRYLCNTSSRMDLNYLQGVDGAIGRCFALITEDG
ERTFAISEGQMNQLRPDSIPEKIFASASALVITAYLVRCKEGDPMPEATMRAIEYAKKYDVPVVLTLGTKFVIQDDPKFW
QEFLRDHVTVVAMNEDEALALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDSAKRETSLPLLPGSVPEFNRYE
FSRPARKESCINPIRVYSHISPYMGGPEKIKNTNGAGDAALSALLHDMAANKYHKENVPNSSKHQHEFLTYSSFSQVCKY
SNRASYEVLAQHSPRLSRGLPEREDSLEEAYWER

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1786684, Length=434, Percent_Identity=75.3456221198157, Blast_Score=710, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.73 [H]

Molecular weight: Translated: 48561; Mature: 48561

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPGQRKSKHYFPVHARDPLVIQAQENKKMSRTHIIGIDQTLVDIEAKVDSDLIERYGL
CCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCEEEEECCHHEEEHHHHCCHHHHHHCCC
SKGHSLVIDDHAAEALYNELKEQRLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDI
CCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCEEEECCHHHHHHHHHCCE
KIGSYGYRYLCNTSSRMDLNYLQGVDGAIGRCFALITEDGERTFAISEGQMNQLRPDSIP
EECCCCEEEEECCCCCCCHHHHHCCCHHHHHEEEEEECCCCEEEEECCCCCCCCCCCCCH
EKIFASASALVITAYLVRCKEGDPMPEATMRAIEYAKKYDVPVVLTLGTKFVIQDDPKFW
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHH
QEFLRDHVTVVAMNEDEALALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDSA
HHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHEEECCCCCHH
KRETSLPLLPGSVPEFNRYEFSRPARKESCINPIRVYSHISPYMGGPEKIKNTNGAGDAA
HHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCHHHHCCCCCCHHHH
LSALLHDMAANKYHKENVPNSSKHQHEFLTYSSFSQVCKYSNRASYEVLAQHSPRLSRGL
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHCCC
PEREDSLEEAYWER
CCHHHHHHHHHCCC
>Mature Secondary Structure
MKFPGQRKSKHYFPVHARDPLVIQAQENKKMSRTHIIGIDQTLVDIEAKVDSDLIERYGL
CCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCEEEEECCHHEEEHHHHCCHHHHHHCCC
SKGHSLVIDDHAAEALYNELKEQRLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDI
CCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCEEEECCHHHHHHHHHCCE
KIGSYGYRYLCNTSSRMDLNYLQGVDGAIGRCFALITEDGERTFAISEGQMNQLRPDSIP
EECCCCEEEEECCCCCCCHHHHHCCCHHHHHEEEEEECCCCEEEEECCCCCCCCCCCCCH
EKIFASASALVITAYLVRCKEGDPMPEATMRAIEYAKKYDVPVVLTLGTKFVIQDDPKFW
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHH
QEFLRDHVTVVAMNEDEALALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDSA
HHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHEEECCCCCHH
KRETSLPLLPGSVPEFNRYEFSRPARKESCINPIRVYSHISPYMGGPEKIKNTNGAGDAA
HHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCHHHHCCCCCCHHHH
LSALLHDMAANKYHKENVPNSSKHQHEFLTYSSFSQVCKYSNRASYEVLAQHSPRLSRGL
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHCCC
PEREDSLEEAYWER
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]