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The map label for this gene is cobA [H]

Identifier: 227081213

GI number: 227081213

Start: 1066181

End: 1066786

Strand: Reverse

Name: cobA [H]

Synonym: VCM66_0995

Alternate gene names: 227081213

Gene position: 1066786-1066181 (Counterclockwise)

Preceding gene: 227081215

Following gene: 227081209

Centisome position: 36.88

GC content: 49.34

Gene sequence:

>606_bases
ATGTCCGGCGATGAAATCAAACAAGAGCGTCACAAAGCTCGTCAACAAAAAGTCAAAGAGCAAGTGGATGCCAAAATTGC
CGCCGCTCAAGAAGAAAAAGGGTTGCTGCTGATTATTACTGGCAATGGTAAAGGAAAATCGACCTCAGGTTTTGGCACCA
TTGCGCGCGCGGTAGGTCACGGTAAACAGTGTGCGGTGGTCCAGTTTATCAAAGGCACTTGGGAGAATGGCGAGCGTAAT
CTTTTAGAAAAGCTCGGCGTTGAATTTCAAGTCATGTCGACTGGCTTTACTTGGGAAACCCAGAACCGCGACAGCGATAC
CGCAGCGGCACAAGAAGTATGGCAACACTGCAAACGTATGTTGCAGGATGAATCGCTGGATGTGGTGCTGTTTGATGAGC
TCACTTACATGGTGAGCTACGGTTACATCGAGTTGGATGAAGTGGTCGAAGCACTCAATCAGCGTCCGAAAATGCAATCG
GTGATCATCACGGGGCGCGGCGCACACCGCACTTTGATTGAGATGGCCGATACGGTTTCTGAAGTGAAAAACATCAAGCA
CGCTTTCGAATCCGGCGTGAAAGCCCTTAAAGGGGTCGATTGGTAA

Upstream 100 bases:

>100_bases
GAGTACCTTCTGCATCTTATATCCCTATTTTTGTTTGGTGTTTGCCACTGACGAGTTGGGCTATCATAGCGACAAGTTTC
AGATTGAAAAAGGATTTGCC

Downstream 100 bases:

>100_bases
AACACTTAAAAAAAATCAATAAGAAAGGGCTGAAATTCAGCCCTTTTTAGTTCATTAGCGATGCATAACCATCAGTTAAA
TAGACCTTTCAACAACCCAT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGHGKQCAVVQFIKGTWENGERN
LLEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRMLQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQS
VIITGRGAHRTLIEMADTVSEVKNIKHAFESGVKALKGVDW

Sequences:

>Translated_201_residues
MSGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGHGKQCAVVQFIKGTWENGERN
LLEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRMLQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQS
VIITGRGAHRTLIEMADTVSEVKNIKHAFESGVKALKGVDW
>Mature_200_residues
SGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGHGKQCAVVQFIKGTWENGERNL
LEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRMLQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQSV
IITGRGAHRTLIEMADTVSEVKNIKHAFESGVKALKGVDW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=67.3469387755102, Blast_Score=295, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22441; Mature: 22310

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCC
GKQCAVVQFIKGTWENGERNLLEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRM
CCCHHHHHHHHCCCCCCHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHH
LQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQSVIITGRGAHRTLIEMADTVS
HCCCCCCEEEHHHHHHHHHCCCEEHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHH
EVKNIKHAFESGVKALKGVDW
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGDEIKQERHKARQQKVKEQVDAKIAAAQEEKGLLLIITGNGKGKSTSGFGTIARAVGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCC
GKQCAVVQFIKGTWENGERNLLEKLGVEFQVMSTGFTWETQNRDSDTAAAQEVWQHCKRM
CCCHHHHHHHHCCCCCCHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHH
LQDESLDVVLFDELTYMVSYGYIELDEVVEALNQRPKMQSVIITGRGAHRTLIEMADTVS
HCCCCCCEEEHHHHHHHHHCCCEEHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHH
EVKNIKHAFESGVKALKGVDW
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]