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The map label for this gene is ybbO [H]

Identifier: 227081153

GI number: 227081153

Start: 1000882

End: 1001709

Strand: Reverse

Name: ybbO [H]

Synonym: VCM66_0935

Alternate gene names: 227081153

Gene position: 1001709-1000882 (Counterclockwise)

Preceding gene: 227081154

Following gene: 227081152

Centisome position: 34.63

GC content: 48.07

Gene sequence:

>828_bases
ATGACCAAATCGATTTTCATTACTGGCTGCTCAAGCGGCATTGGTTACATGGCGGCGAAACAATTGCAGTTACGGGGTTA
TCAGGTGATAGCATCATGTCGTGATGCACAAGATGTTGCGCGCCTATCCCAAGAGAGTTTGACCTGCATTCAACTGGATC
TCACCTGTGAAGCCAGCATCAACCAAGCGGTAGAGCAAGCGCTAGAACTTTCCAACCATCGGCTTTATGCACTGTTTAAT
AACGGAGCTTATGGCCAACCGGGCGCTTTGGAAGACTTACCCGTACAAGCTATGCGCGAACAGTTCGAAGCCAATTTTTT
TGGCTGGCATCATCTGACGACCCGCTTGCTTCCTCACTTTCGTCGTCAAGGTTACGGACGCATTATTCAAAACAGCTCTG
TACTTGGCTTTGCCGCCATGAAATACCGCGGTGCTTACAATGCTTCCAAGTTTGCCATCGAGGGCTGGACGGATACCTTA
AGACTGGAGTTGCAAGGGTCGGATATTCATATCAGTTTGATTGAACCTGGTCCGATTGAAACTCAATTTCGCGCCAATGC
CTTACACGCCTTTAAGCGCTGGGTAAACATCGAACAAAGTGTTCACCACCTCGCCTACCAACAACAAATGCAACGTTTGA
GCAAAACGCACTCCAACAACCGCTTTGTCTTACCGCCAGAGGCTTGTCTAGCACCACTTTGCCATGCTCTGGAAGCACGC
AAACCGAAGATCCGTTATCGCATTACGACGCCAACCAAAGTCTTTGCGGTATTAAAGCGACTTTTACCCACACGCTGGCT
AGACAAATTATTATTTAAAGCCGCATAA

Upstream 100 bases:

>100_bases
GTTCCACTATTCACGCATTGATCGAGCCTTTAATCAGCTCCTTACGGCATCACAATAAGCCATAACGGACACAAGCAAAC
GCATACATAATAGGATTGCG

Downstream 100 bases:

>100_bases
ATTATTTAATTGTCATTATTTGGTAACAATTGCGCGGCAAACTTCATAATGCTCACTGGATTAACTCCTAGACATTGAGT
AAAAACATCAATATCTATCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTKSIFITGCSSGIGYMAAKQLQLRGYQVIASCRDAQDVARLSQESLTCIQLDLTCEASINQAVEQALELSNHRLYALFN
NGAYGQPGALEDLPVQAMREQFEANFFGWHHLTTRLLPHFRRQGYGRIIQNSSVLGFAAMKYRGAYNASKFAIEGWTDTL
RLELQGSDIHISLIEPGPIETQFRANALHAFKRWVNIEQSVHHLAYQQQMQRLSKTHSNNRFVLPPEACLAPLCHALEAR
KPKIRYRITTPTKVFAVLKRLLPTRWLDKLLFKAA

Sequences:

>Translated_275_residues
MTKSIFITGCSSGIGYMAAKQLQLRGYQVIASCRDAQDVARLSQESLTCIQLDLTCEASINQAVEQALELSNHRLYALFN
NGAYGQPGALEDLPVQAMREQFEANFFGWHHLTTRLLPHFRRQGYGRIIQNSSVLGFAAMKYRGAYNASKFAIEGWTDTL
RLELQGSDIHISLIEPGPIETQFRANALHAFKRWVNIEQSVHHLAYQQQMQRLSKTHSNNRFVLPPEACLAPLCHALEAR
KPKIRYRITTPTKVFAVLKRLLPTRWLDKLLFKAA
>Mature_274_residues
TKSIFITGCSSGIGYMAAKQLQLRGYQVIASCRDAQDVARLSQESLTCIQLDLTCEASINQAVEQALELSNHRLYALFNN
GAYGQPGALEDLPVQAMREQFEANFFGWHHLTTRLLPHFRRQGYGRIIQNSSVLGFAAMKYRGAYNASKFAIEGWTDTLR
LELQGSDIHISLIEPGPIETQFRANALHAFKRWVNIEQSVHHLAYQQQMQRLSKTHSNNRFVLPPEACLAPLCHALEARK
PKIRYRITTPTKVFAVLKRLLPTRWLDKLLFKAA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=196, Percent_Identity=37.2448979591837, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI40548397, Length=287, Percent_Identity=31.0104529616725, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI214010158, Length=287, Percent_Identity=31.0104529616725, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI214010156, Length=287, Percent_Identity=31.0104529616725, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI22758144, Length=287, Percent_Identity=31.0104529616725, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI19743808, Length=283, Percent_Identity=30.3886925795053, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI150247226, Length=280, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI223718074, Length=269, Percent_Identity=30.8550185873606, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI22507405, Length=279, Percent_Identity=30.1075268817204, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI44680136, Length=265, Percent_Identity=25.6603773584906, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI44680133, Length=265, Percent_Identity=25.6603773584906, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI17738292, Length=265, Percent_Identity=25.6603773584906, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI50726952, Length=280, Percent_Identity=29.6428571428571, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI119392083, Length=199, Percent_Identity=32.6633165829146, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=30.1507537688442, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI4504503, Length=215, Percent_Identity=29.3023255813954, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=235, Percent_Identity=28.5106382978723, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=30.1075268817204, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1786701, Length=271, Percent_Identity=43.1734317343173, Blast_Score=223, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI71997402, Length=217, Percent_Identity=29.9539170506912, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17570069, Length=216, Percent_Identity=29.6296296296296, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17557780, Length=265, Percent_Identity=27.5471698113208, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534660, Length=288, Percent_Identity=25.6944444444444, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193210355, Length=278, Percent_Identity=26.6187050359712, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32563809, Length=292, Percent_Identity=24.6575342465753, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=292, Percent_Identity=24.6575342465753, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=34.1836734693878, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24580925, Length=193, Percent_Identity=29.5336787564767, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24651139, Length=295, Percent_Identity=29.1525423728814, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=28.1914893617021, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24641232, Length=200, Percent_Identity=27, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24644339, Length=222, Percent_Identity=24.3243243243243, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31214; Mature: 31083

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSIFITGCSSGIGYMAAKQLQLRGYQVIASCRDAQDVARLSQESLTCIQLDLTCEASI
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEECHHH
NQAVEQALELSNHRLYALFNNGAYGQPGALEDLPVQAMREQFEANFFGWHHLTTRLLPHF
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
RRQGYGRIIQNSSVLGFAAMKYRGAYNASKFAIEGWTDTLRLELQGSDIHISLIEPGPIE
HHCCCCCEECCCCCHHHHHHHHCCCCCCCEEEEECCCEEEEEEEECCEEEEEEECCCCCC
TQFRANALHAFKRWVNIEQSVHHLAYQQQMQRLSKTHSNNRFVLPPEACLAPLCHALEAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCC
KPKIRYRITTPTKVFAVLKRLLPTRWLDKLLFKAA
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKSIFITGCSSGIGYMAAKQLQLRGYQVIASCRDAQDVARLSQESLTCIQLDLTCEASI
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEECHHH
NQAVEQALELSNHRLYALFNNGAYGQPGALEDLPVQAMREQFEANFFGWHHLTTRLLPHF
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
RRQGYGRIIQNSSVLGFAAMKYRGAYNASKFAIEGWTDTLRLELQGSDIHISLIEPGPIE
HHCCCCCEECCCCCHHHHHHHHCCCCCCCEEEEECCCEEEEEEEECCEEEEEEECCCCCC
TQFRANALHAFKRWVNIEQSVHHLAYQQQMQRLSKTHSNNRFVLPPEACLAPLCHALEAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCC
KPKIRYRITTPTKVFAVLKRLLPTRWLDKLLFKAA
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]