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The map label for this gene is rodA [H]

Identifier: 227081123

GI number: 227081123

Start: 970518

End: 971639

Strand: Reverse

Name: rodA [H]

Synonym: VCM66_0905

Alternate gene names: 227081123

Gene position: 971639-970518 (Counterclockwise)

Preceding gene: 227081124

Following gene: 227081122

Centisome position: 33.59

GC content: 48.57

Gene sequence:

>1122_bases
ATGAAGATGGATCCTGCAACCGGACAAAACCGGGCGCTGTTTGAGCGTTTTCATATTGATCTGCCTCTACTGCTTGGCGT
TCTTGCCCTAATGGGATTTGGCTTAGTGGTGATGTACAGCGCCAGTGGTCAGAGCCTAGCGATGATGGATCGCCAAGCCA
TGCGCATGGCCATGGCTCTCATCATCATGGTGATTCTGGCGCAAATTCCACCGCGTACCTATGAGAGTGCTGCGCCTATC
CTATTTTTTTGCGGCGTCATATTGTTGGTGTGTGTACTGCTGTTTGGGGAAATCTCCAAAGGCGCGCAACGTTGGCTAGA
TCTCGGTTTTGTCCGTTTTCAGCCTTCAGAACTGCTCAAACTCGCCGTACCTTTGATGGTGGCACGTTACATCGGCAAAC
ACGCCCTGCCACCGTCGTTCAAAACCTTATTCGCCTCGTTGGTAATGGTGTTCGTTCCAACCATTTTAATTGCGAAACAG
CCCGACCTTGGCACCTCAATTTTGATTGCAGCCTCGGGCATTTTTGTAATCTTCTTGGCGGGCATTAGCTGGAAGCTGAT
TACTGCAGCGGCCGTGGCCATCGGCGCTTTTGTGCCTGTGCTGTGGTTCTTCCTGATGCACGAATACCAAAAAACCCGCG
TGCGTACTTTGTTTGATCCTGAATCTGACCCTCTTGGCGCTGGCTATCACATCATCCAAAGTAAAATTGCGATTGGTTCA
GGTGGCTTGTCAGGAAAAGGCTGGTTACACGGCACACAATCACAACTTGAATTTCTTCCTGAACGACATACTGACTTTAT
CTTTGCAGTCATTGCCGAAGAATGGGGTATGATCGGCATCTTAGTCCTACTCAGCCTCTATTTATTTATTATTGGTCGTG
GACTTTATCTCGCTAGCCATGCACAAACGTCCTTTGGGCGTATGATGGCTGGCAGTATCGTATTGAGCTTCTTTGTTTAT
GTGTTTGTGAACATAGGCATGGTGAGCGGAATTTTACCTGTGGTGGGTGTTCCACTACCACTGATTAGTTATGGTGGAAC
GTCGATGGTGACACTGATGGCCGGTTTCGGTATTTTGATGTCCATCCATACGCACCGCAAAGCGTTTTCGAAGACGATTT
AA

Upstream 100 bases:

>100_bases
GTAATGGTGCGCCAGTCGTGCGACAAATTTTCGATCACGTGATTTTGGGCAAAAAAGAAGAAGAGCCAAAAGCAGAATCA
AAAGAAGAGGTAATACAGCC

Downstream 100 bases:

>100_bases
TGAACCGAATTTATTTATACTTACTGCTCGTTTTAATCCTCGCTGGATGTAGCTCTCCGGGGGGGCGCTATGATATGTCT
GACGATCAAGCACCCGATAC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKMDPATGQNRALFERFHIDLPLLLGVLALMGFGLVVMYSASGQSLAMMDRQAMRMAMALIIMVILAQIPPRTYESAAPI
LFFCGVILLVCVLLFGEISKGAQRWLDLGFVRFQPSELLKLAVPLMVARYIGKHALPPSFKTLFASLVMVFVPTILIAKQ
PDLGTSILIAASGIFVIFLAGISWKLITAAAVAIGAFVPVLWFFLMHEYQKTRVRTLFDPESDPLGAGYHIIQSKIAIGS
GGLSGKGWLHGTQSQLEFLPERHTDFIFAVIAEEWGMIGILVLLSLYLFIIGRGLYLASHAQTSFGRMMAGSIVLSFFVY
VFVNIGMVSGILPVVGVPLPLISYGGTSMVTLMAGFGILMSIHTHRKAFSKTI

Sequences:

>Translated_373_residues
MKMDPATGQNRALFERFHIDLPLLLGVLALMGFGLVVMYSASGQSLAMMDRQAMRMAMALIIMVILAQIPPRTYESAAPI
LFFCGVILLVCVLLFGEISKGAQRWLDLGFVRFQPSELLKLAVPLMVARYIGKHALPPSFKTLFASLVMVFVPTILIAKQ
PDLGTSILIAASGIFVIFLAGISWKLITAAAVAIGAFVPVLWFFLMHEYQKTRVRTLFDPESDPLGAGYHIIQSKIAIGS
GGLSGKGWLHGTQSQLEFLPERHTDFIFAVIAEEWGMIGILVLLSLYLFIIGRGLYLASHAQTSFGRMMAGSIVLSFFVY
VFVNIGMVSGILPVVGVPLPLISYGGTSMVTLMAGFGILMSIHTHRKAFSKTI
>Mature_373_residues
MKMDPATGQNRALFERFHIDLPLLLGVLALMGFGLVVMYSASGQSLAMMDRQAMRMAMALIIMVILAQIPPRTYESAAPI
LFFCGVILLVCVLLFGEISKGAQRWLDLGFVRFQPSELLKLAVPLMVARYIGKHALPPSFKTLFASLVMVFVPTILIAKQ
PDLGTSILIAASGIFVIFLAGISWKLITAAAVAIGAFVPVLWFFLMHEYQKTRVRTLFDPESDPLGAGYHIIQSKIAIGS
GGLSGKGWLHGTQSQLEFLPERHTDFIFAVIAEEWGMIGILVLLSLYLFIIGRGLYLASHAQTSFGRMMAGSIVLSFFVY
VFVNIGMVSGILPVVGVPLPLISYGGTSMVTLMAGFGILMSIHTHRKAFSKTI

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=365, Percent_Identity=65.7534246575342, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1786277, Length=362, Percent_Identity=32.8729281767956, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40708; Mature: 40708

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]