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The map label for this gene is dadA [H]

Identifier: 227080965

GI number: 227080965

Start: 799818

End: 801083

Strand: Reverse

Name: dadA [H]

Synonym: VCM66_0744

Alternate gene names: 227080965

Gene position: 801083-799818 (Counterclockwise)

Preceding gene: 227080969

Following gene: 227080964

Centisome position: 27.69

GC content: 51.18

Gene sequence:

>1266_bases
ATGATGGAAGTTTTGGTTTTAGGCAGTGGTGTGGTCGGATTAACCAGCGCTTGGTATCTTGCGCAGGCAGGCCATGATGT
CACCGTCGTCGATCGCCAACCACGTGGCGCCGAAGAAACCAGCTTTGCGAACGCAGGGCAAATCTCCTATGGCTACTCTT
CCCCTTGGGCTGCGCCGGGCATTCCGCAAAAAGCGCTAAAATGGATGCTGGAAAAACATGCACCACTCAAAATCCAACCC
TCGCTTGATCCTGCATTACTGAGCTGGATGGGCAAAATGCTGCTCAACTGCCAGTTGTCGCGCTACCAAGTTAACAAATC
GCGGATGTTGGCGATTGCCAACTATAGCCGCGAGTGTTTAAAAGCGCTCAATCAAACCTATTCGCTCGATTACCAAGGCC
GCCAACGCGGTACTTTGCAGGTATTTCGTGATGAAAAGCAGTTAACCGCGATTGAAAAAGACATGCAGCTTCTGGCGCAA
AGTGGCGTACGTTTTGAGTTACTGAATGTCGCCCAGTGTCTGACTCATGAACCGGGGCTCGCCCCTGTGCAGGAAAAACT
GGTGGGCGGCCTATGGCTGCCGGATGACGAAACGGGCGATTGTTACTTGTTTTGCCAACAGTTAACCGAACTGGCCAAGC
AACAGGGTGTACGTTTTCATTTTGACTGCCACATTCAGCAACTGGTTTGTGAGGGCAAAAAGATCATCGGTGTCCAAACC
GATTTAGGCTTGCTCAAAGCGGATGCTTATGTAGTCGCATTGGGCAGTTATTCGACCTCATTGCTTAAACCGCTGGGGAT
TGAAATTCCTGTCTACCCAGTAAAAGGATACTCGTTAACCTTACCGATTATTGATGAAAAATTTGCGCCGCAATCGACCG
TGATGGATGAAACCTATAAGGTTGCACTGACTCGCTTTTCCGATCGGATCCGCGTGGCGGGAACGGCTGAGTTAGCGGGT
TTTGATCCAGCGATTCCAGAAGCACGTAAAGCGACGATTGAGATGGTCGCGCGTGATTTGTTTCCGCACGGCGGCGATTT
TGCAAAAGGGCAATTCTGGACCGGTTTTCGTCCCATGACTCCCGATGGCACACCAATCATCGGTGCCACTCCCTATACCA
ATCTCTATACAAATACTGGGCATGGCACACTGGGATGGACCATGGCTTGCGGATCCGCCAGTATTCTGGCCGATGTGCTC
ACCCATGGCGAAAGCCCGCTCAGCCGTTTGGGGCTAGATCTGTTCCGTTATCCGAAAGCATCTTAA

Upstream 100 bases:

>100_bases
GGACTTGCTTTTAGTTTTACTAAAGGGTGGTGATAATTTTTATCGATTGTTAATGAAAAGTAAACCTCCGAAACTGAGCC
GAAAATGAAGCAAGGAGTCA

Downstream 100 bases:

>100_bases
ATGCGCGGCTTTTTGGCTCTGCCTGCAGGAGCATGGCAGAGTCATCTCTCACAATCCGCACGCCATCCGCACGCCATCCG
CAGTGTAAAACTCCAATAAG

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPGIPQKALKWMLEKHAPLKIQP
SLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECLKALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQ
SGVRFELLNVAQCLTHEPGLAPVQEKLVGGLWLPDDETGDCYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYKVALTRFSDRIRVAGTAELAG
FDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMTPDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVL
THGESPLSRLGLDLFRYPKAS

Sequences:

>Translated_421_residues
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPGIPQKALKWMLEKHAPLKIQP
SLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECLKALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQ
SGVRFELLNVAQCLTHEPGLAPVQEKLVGGLWLPDDETGDCYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYKVALTRFSDRIRVAGTAELAG
FDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMTPDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVL
THGESPLSRLGLDLFRYPKAS
>Mature_421_residues
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPGIPQKALKWMLEKHAPLKIQP
SLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECLKALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQ
SGVRFELLNVAQCLTHEPGLAPVQEKLVGGLWLPDDETGDCYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYKVALTRFSDRIRVAGTAELAG
FDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMTPDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVL
THGESPLSRLGLDLFRYPKAS

Specific function: Oxidative deamination of D-amino acids [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787438, Length=419, Percent_Identity=54.1766109785203, Blast_Score=482, Evalue=1e-137,
Organism=Drosophila melanogaster, GI28571104, Length=328, Percent_Identity=26.219512195122, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023080
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.99.1 [H]

Molecular weight: Translated: 46268; Mature: 46268

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPG
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCC
IPQKALKWMLEKHAPLKIQPSLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECL
CCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCHHHEECCCHHEEEEHHHHHHHH
KALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQSGVRFELLNVAQCLTHEPGL
HHHHHHEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCC
APVQEKLVGGLWLPDDETGDCYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
CHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCEEEEEEC
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYK
CCCCEECCEEEEEECCCCHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHH
VALTRFSDRIRVAGTAELAGFDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMT
HHHHHHCCCEEEEEEHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCC
PDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVLTHGESPLSRLGLDLFRYPKA
CCCCEEECCCCCCCCEECCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHHCHHHHCCCCC
S
C
>Mature Secondary Structure
MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPG
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCC
IPQKALKWMLEKHAPLKIQPSLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECL
CCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCHHHEECCCHHEEEEHHHHHHHH
KALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQSGVRFELLNVAQCLTHEPGL
HHHHHHEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCC
APVQEKLVGGLWLPDDETGDCYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQT
CHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCEEEEEEC
DLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYK
CCCCEECCEEEEEECCCCHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHH
VALTRFSDRIRVAGTAELAGFDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMT
HHHHHHCCCEEEEEEHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCC
PDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVLTHGESPLSRLGLDLFRYPKA
CCCCEEECCCCCCCCEECCCCCCCEEEEECCCHHHHHHHHHCCCCCHHHHCHHHHCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA