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The map label for this gene is mreB [H]

Identifier: 227080626

GI number: 227080626

Start: 426882

End: 427925

Strand: Direct

Name: mreB [H]

Synonym: VCM66_0400

Alternate gene names: 227080626

Gene position: 426882-427925 (Clockwise)

Preceding gene: 227080625

Following gene: 227080627

Centisome position: 14.76

GC content: 50.77

Gene sequence:

>1044_bases
ATGTTCAAAAAACTTCGTGGCATGTTTTCTAACGACCTATCGATCGATTTAGGTACCGCCAACACACTTATTTATGTCAA
AGGACAGGGAATTGTTCTTGATGAACCTTCTGTTGTTGCAATTCGTCAAGACAAAGGTCGTGGCGGTAAAACCGTTGCAG
CGGTTGGCCATGCCGCAAAACAGATGCTCGGTAGAACCCCTGGTAATATTTCAGCCATTCGCCCAATGAAAGACGGTGTT
ATTGCTGATTTTTACGTCACTGAAAAAATGCTGCAGCATTTTATTCGCCAAGTGCACGACAACAGCGTGTTAAAGCCAAG
CCCACGCGTACTGGTGTGTGTGCCTTGTGGTTCAACCCAAGTTGAGCGTCGTGCGATCCGTGAATCGGCACTGGGTGCGG
GCGCTCGTGAGGTTTACTTGATTGATGAACCAATGGCGGCCGCCATCGGTGCTGGTTTGCGCGTTTCTGAGCCAACCGGT
TCAATGGTGATTGATATCGGTGGTGGTACGACGGAAGTGGCGGTGATCTCGCTCAATGGCGTGGTTTACTCTTCTTCTGT
GCGTATCGGTGGTGACCGTTTTGATGAAGCGATCATTAATTATGTGCGCCGTAACTACGGTAGCTTGATTGGTGAAGCCA
CTGCAGAAAAGATCAAACACGAAATTGGCTCAGCTTATCCGGGCGATGACGTGCAAGAGATCGAAGTGCGCGGTCGTAAC
CTAGCAGAAGGTGTACCACGCAGTTTCACACTGAATTCGAACGAGATCCTTGAGGCGCTGCAAGAGCCGCTGACGGGGAT
TGTGTCTGCGGTGATGGTTGCACTCGAGCAGTGTCCACCAGAGCTGGCTTCAGATATCTCTGAAAACGGTATGGTTCTCA
CAGGCGGCGGTGCACTGCTGAAAGATCTGGATCGTCTGCTAATGGAAGAGACTGGCATTCCTGTGGTGATCGCCGATGAC
CCGCTGACCTGTGTGGCGCGTGGGGGTGGTAAAGCCTTAGAAATGATCGATATGCACGGCGGCGATCTGTTTAGCGAAGA
ATAA

Upstream 100 bases:

>100_bases
CAGTCCATGTTTATGGATCAACGCCTTGCTGTGATGGCAAGGCATTGGTACATTTAGTGCAATTTTCCTTTTCTCATTTC
TTGCAGGACGAACGAAGAAT

Downstream 100 bases:

>100_bases
ACCGTAGTGTTGTGCCTTATGCATGGCACTTTGCTCAGAGTTAGGATGGTTATTGGATGAAACCTATCTTTGGTCGAGGA
CCTTCTCTGCAGCTACGGCT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDKGRGGKTVAAVGHAAKQMLGRTPGNISAIRPMKDGV
IADFYVTEKMLQHFIRQVHDNSVLKPSPRVLVCVPCGSTQVERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTG
SMVIDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDDVQEIEVRGRN
LAEGVPRSFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISENGMVLTGGGALLKDLDRLLMEETGIPVVIADD
PLTCVARGGGKALEMIDMHGGDLFSEE

Sequences:

>Translated_347_residues
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDKGRGGKTVAAVGHAAKQMLGRTPGNISAIRPMKDGV
IADFYVTEKMLQHFIRQVHDNSVLKPSPRVLVCVPCGSTQVERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTG
SMVIDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDDVQEIEVRGRN
LAEGVPRSFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISENGMVLTGGGALLKDLDRLLMEETGIPVVIADD
PLTCVARGGGKALEMIDMHGGDLFSEE
>Mature_347_residues
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDKGRGGKTVAAVGHAAKQMLGRTPGNISAIRPMKDGV
IADFYVTEKMLQHFIRQVHDNSVLKPSPRVLVCVPCGSTQVERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTG
SMVIDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDDVQEIEVRGRN
LAEGVPRSFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISENGMVLTGGGALLKDLDRLLMEETGIPVVIADD
PLTCVARGGGKALEMIDMHGGDLFSEE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=90.2017291066282, Blast_Score=636, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36902; Mature: 36902

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDKGRGGKTVAAVGHAAK
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCHHHHHHHHH
QMLGRTPGNISAIRPMKDGVIADFYVTEKMLQHFIRQVHDNSVLKPSPRVLVCVPCGSTQ
HHHCCCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHH
VERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTGSMVIDIGGGTTEVAVISLNG
HHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCEEECCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDDVQEIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCH
LAEGVPRSFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISENGMVLTGGGALL
HHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCHHH
KDLDRLLMEETGIPVVIADDPLTCVARGGGKALEMIDMHGGDLFSEE
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDKGRGGKTVAAVGHAAK
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCHHHHHHHHH
QMLGRTPGNISAIRPMKDGVIADFYVTEKMLQHFIRQVHDNSVLKPSPRVLVCVPCGSTQ
HHHCCCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHH
VERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTGSMVIDIGGGTTEVAVISLNG
HHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCEEECCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDDVQEIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCH
LAEGVPRSFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISENGMVLTGGGALL
HHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCHHH
KDLDRLLMEETGIPVVIADDPLTCVARGGGKALEMIDMHGGDLFSEE
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]