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The map label for this gene is hflX [H]

Identifier: 227080560

GI number: 227080560

Start: 355172

End: 356461

Strand: Direct

Name: hflX [H]

Synonym: VCM66_0332

Alternate gene names: 227080560

Gene position: 355172-356461 (Clockwise)

Preceding gene: 227080559

Following gene: 227080561

Centisome position: 12.28

GC content: 48.06

Gene sequence:

>1290_bases
TTGTTTGACCGTTATGAAGCCGGTGAGCGAGCCGTACTTGTTCATGTCAACTTCACGCAACGGGGTGAGTGGGAAGATCT
GAGCGAATGTAAAATGCTCATTTCTTCCGCAGGGGTGACAACACTGCATGTGGTAACAGGCAGTCGTCAGACCCCTCACC
CTAAATATTTCGTTGGTGAGGGCAAAGCCCAAGAAATCGCCGAAGCCGTGCAAATGCATGTTGCTAATGTGGTGATTTTT
AACCACGCTCTTTCTCCTGCCCAAGAACGTAACCTCGAAAGACTGTGCCAATGTCGAGTCATTGATCGTACAGGTCTTAT
CCTTGATATCTTCGCTCAACGTGCTCGTACCCATGAAGGCAAGCTACAAGTCGAGTTGGCTCAGTTGCGCCATATCTCTA
CTCGCTTAATTCGTGGCTGGACGCACTTAGAAAGACAAAAAGGCGGGATTGGTTTACGTGGGCCGGGTGAAACCCAGCTT
GAAACAGACCGACGTTTACTGCGTGAACGGATTAAAGCGATTTTGCGCCGCTTAGAAAAAGTGGCCAAACAGCGTGAACA
AGGGCGCCGTGCTCGTAGCCGTGCAGAAATTCCAACCATCTCGTTGGTGGGTTATACCAACGCAGGGAAATCTACCCTGT
TTAACCGAATCACTGAAGCCGGTGTGTATGCGGCGGATCAATTGTTCGCAACACTCGATCCTACTTTGCGTAAAATCGAT
CTGGTGGATGTAGGGCCGGCCGTTTTAGCCGACACAGTAGGTTTTATTCGCCATCTTCCGCATGATCTTGTTGCGGCTTT
TAAAGCGACGTTACAAGAGACACAAGAAGCTGACATTTTGTTACATGTTGTTGATGCCAGTGACGAACGCTTTCGTGAGA
ATATCCAAGCGGTAGAGACTGTTTTACAAGAGATTGATGCTCATGAAGTCCCCACTTTGTTGGTGATGAATAAGATCGAT
AATCTCGAAGAGCAATCTCCACGTATAGAACGGGATGATGAAGGCGTTCCGAGAGTAGTGTGGATCTCTGCCATGCAGGG
CGCGGGTACTGAGCTACTCTTTGAGGCATTGAGTGAGCGTTTGGCTAGCCAAGTGGTGGAGCATCACTTACGTATTCCGC
CGCGACATCAAGGACGTATCCGTAGCACATTTTTCCAAATGAACTGTATTCAACAGGAAGAGTATGATCCGGAAGGCAAT
TTACTGATCACTGTGCGGATGCAACAGGTCGATTGGGCTAGACTAGAAAAACGAGAGCAAGCAGATTTATGTGACTTTAT
AGTTACTTAA

Upstream 100 bases:

>100_bases
GTCCAGTTAGCCACCACAGCGGCGACCGCCCAGCATCGGATCGTCCAGCAGAGAAGTCTGAAGAGTAATTCTTTGCACAA
TTATTTAAGGAGTTGATCGC

Downstream 100 bases:

>100_bases
AGGACTGCTAGAGTATAACGTCATATCAAATGATGGAGTTTTCTAATGGCGTGGAATGAGCCTGGTAATAATAACGGCAA
CAATGGCCGCGATAATGACC

Product: putative GTPase HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MFDRYEAGERAVLVHVNFTQRGEWEDLSECKMLISSAGVTTLHVVTGSRQTPHPKYFVGEGKAQEIAEAVQMHVANVVIF
NHALSPAQERNLERLCQCRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRERIKAILRRLEKVAKQREQGRRARSRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKID
LVDVGPAVLADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDERFRENIQAVETVLQEIDAHEVPTLLVMNKID
NLEEQSPRIERDDEGVPRVVWISAMQGAGTELLFEALSERLASQVVEHHLRIPPRHQGRIRSTFFQMNCIQQEEYDPEGN
LLITVRMQQVDWARLEKREQADLCDFIVT

Sequences:

>Translated_429_residues
MFDRYEAGERAVLVHVNFTQRGEWEDLSECKMLISSAGVTTLHVVTGSRQTPHPKYFVGEGKAQEIAEAVQMHVANVVIF
NHALSPAQERNLERLCQCRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRERIKAILRRLEKVAKQREQGRRARSRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKID
LVDVGPAVLADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDERFRENIQAVETVLQEIDAHEVPTLLVMNKID
NLEEQSPRIERDDEGVPRVVWISAMQGAGTELLFEALSERLASQVVEHHLRIPPRHQGRIRSTFFQMNCIQQEEYDPEGN
LLITVRMQQVDWARLEKREQADLCDFIVT
>Mature_429_residues
MFDRYEAGERAVLVHVNFTQRGEWEDLSECKMLISSAGVTTLHVVTGSRQTPHPKYFVGEGKAQEIAEAVQMHVANVVIF
NHALSPAQERNLERLCQCRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRERIKAILRRLEKVAKQREQGRRARSRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKID
LVDVGPAVLADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDERFRENIQAVETVLQEIDAHEVPTLLVMNKID
NLEEQSPRIERDDEGVPRVVWISAMQGAGTELLFEALSERLASQVVEHHLRIPPRHQGRIRSTFFQMNCIQQEEYDPEGN
LLITVRMQQVDWARLEKREQADLCDFIVT

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=270, Percent_Identity=33.7037037037037, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI310133118, Length=272, Percent_Identity=33.4558823529412, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI310124269, Length=252, Percent_Identity=34.1269841269841, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124267, Length=252, Percent_Identity=34.1269841269841, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124171, Length=252, Percent_Identity=34.1269841269841, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124169, Length=252, Percent_Identity=34.1269841269841, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1790615, Length=428, Percent_Identity=71.7289719626168, Blast_Score=626, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561038, Length=287, Percent_Identity=30.3135888501742, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24650079, Length=288, Percent_Identity=30.5555555555556, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48793; Mature: 48793

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYEAGERAVLVHVNFTQRGEWEDLSECKMLISSAGVTTLHVVTGSRQTPHPKYFVGE
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECC
GKAQEIAEAVQMHVANVVIFNHALSPAQERNLERLCQCRVIDRTGLILDIFAQRARTHEG
CCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
KLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRERIKAILRRLEK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARSRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKID
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEE
LVDVGPAVLADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDERFRENIQAVET
EECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHH
VLQEIDAHEVPTLLVMNKIDNLEEQSPRIERDDEGVPRVVWISAMQGAGTELLFEALSER
HHHHHCHHCCCHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
LASQVVEHHLRIPPRHQGRIRSTFFQMNCIQQEEYDPEGNLLITVRMQQVDWARLEKREQ
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHH
ADLCDFIVT
HHHHHHHCC
>Mature Secondary Structure
MFDRYEAGERAVLVHVNFTQRGEWEDLSECKMLISSAGVTTLHVVTGSRQTPHPKYFVGE
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECC
GKAQEIAEAVQMHVANVVIFNHALSPAQERNLERLCQCRVIDRTGLILDIFAQRARTHEG
CCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
KLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRERIKAILRRLEK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARSRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKID
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEE
LVDVGPAVLADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDERFRENIQAVET
EECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHH
VLQEIDAHEVPTLLVMNKIDNLEEQSPRIERDDEGVPRVVWISAMQGAGTELLFEALSER
HHHHHCHHCCCHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
LASQVVEHHLRIPPRHQGRIRSTFFQMNCIQQEEYDPEGNLLITVRMQQVDWARLEKREQ
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHH
ADLCDFIVT
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]