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The map label for this gene is gntV [H]

Identifier: 227080501

GI number: 227080501

Start: 281095

End: 281610

Strand: Direct

Name: gntV [H]

Synonym: VCM66_0272

Alternate gene names: 227080501

Gene position: 281095-281610 (Clockwise)

Preceding gene: 227080495

Following gene: 227080502

Centisome position: 9.72

GC content: 50.39

Gene sequence:

>516_bases
ATGGCCGGTAGTAGCATCATTGTGATGGGGGTTTGTGCTTGCGGTAAAAGCACCATTGGTGAGTTATTGGCAAAGCAGAC
TGGGCGAAAATTCATTGATGGCGATGATCTTCATCCGCGTGCCAATATTCAGAAAATGGCCTCCGGCCAGCCGCTCAATG
ATGAAGATCGTAAACCTTGGTTAGAGCGCATCCGCGATGCCGCTTACAGCCTCGAAAGCAAAAACGAACATGGGGTGATT
GTCTGCTCGGCACTCAAAAAGCAGTACCGCGACCAGATCCGCGAAGGCAACCAAAACGTGACATTCTTGTTCTTGGATGG
CTCGAAAGAGCTGATCATGGAGCGCATGCGCGCTCGCCAAGGCCATTTCATGAAAGAGAACATGGTCAACAGTCAGTTTG
AAACCTTAGAGCGCCCTGATGGTGAGCCGCAAACCCTGATCATCCCTATTGATTGTTCAGTGCAGGAAGTGGTGAATTGT
GCGATTCAAGCACTGCAAGAGCAGGAGGGTCTATGA

Upstream 100 bases:

>100_bases
ACCGGTAACATGTTACCCATAACATGAATAAGATAAACCCATATTTCGAAGTGAATTTTAAAAATGCGATCACGCGCAAG
TTTGGTTTTAAGGAGTCGTT

Downstream 100 bases:

>100_bases
TTCATCCTGTTTTAGCCAAAGTTACTGAAAATCTCATCGAGCGTAGCCGTGAAGCACGTGCGGCGTTTATTGCACGCAGT
CAAGCACAAGAAAAAGCCGG

Product: thermoresistant gluconokinase

Products: NA

Alternate protein names: Gluconate kinase 1 [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MAGSSIIVMGVCACGKSTIGELLAKQTGRKFIDGDDLHPRANIQKMASGQPLNDEDRKPWLERIRDAAYSLESKNEHGVI
VCSALKKQYRDQIREGNQNVTFLFLDGSKELIMERMRARQGHFMKENMVNSQFETLERPDGEPQTLIIPIDCSVQEVVNC
AIQALQEQEGL

Sequences:

>Translated_171_residues
MAGSSIIVMGVCACGKSTIGELLAKQTGRKFIDGDDLHPRANIQKMASGQPLNDEDRKPWLERIRDAAYSLESKNEHGVI
VCSALKKQYRDQIREGNQNVTFLFLDGSKELIMERMRARQGHFMKENMVNSQFETLERPDGEPQTLIIPIDCSVQEVVNC
AIQALQEQEGL
>Mature_170_residues
AGSSIIVMGVCACGKSTIGELLAKQTGRKFIDGDDLHPRANIQKMASGQPLNDEDRKPWLERIRDAAYSLESKNEHGVIV
CSALKKQYRDQIREGNQNVTFLFLDGSKELIMERMRARQGHFMKENMVNSQFETLERPDGEPQTLIIPIDCSVQEVVNCA
IQALQEQEGL

Specific function: Gluconate utilization system GNT-II. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=183, Percent_Identity=38.7978142076503, Blast_Score=134, Evalue=5e-32,
Organism=Escherichia coli, GI1790719, Length=166, Percent_Identity=54.2168674698795, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI87082265, Length=162, Percent_Identity=48.1481481481481, Blast_Score=174, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25146487, Length=170, Percent_Identity=37.6470588235294, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320454, Length=157, Percent_Identity=43.9490445859873, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 19208; Mature: 19077

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSSIIVMGVCACGKSTIGELLAKQTGRKFIDGDDLHPRANIQKMASGQPLNDEDRKPW
CCCCCEEEEHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHH
LERIRDAAYSLESKNEHGVIVCSALKKQYRDQIREGNQNVTFLFLDGSKELIMERMRARQ
HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
GHFMKENMVNSQFETLERPDGEPQTLIIPIDCSVQEVVNCAIQALQEQEGL
CCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGSSIIVMGVCACGKSTIGELLAKQTGRKFIDGDDLHPRANIQKMASGQPLNDEDRKPW
CCCCEEEEHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHH
LERIRDAAYSLESKNEHGVIVCSALKKQYRDQIREGNQNVTFLFLDGSKELIMERMRARQ
HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
GHFMKENMVNSQFETLERPDGEPQTLIIPIDCSVQEVVNCAIQALQEQEGL
CCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]