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The map label for this gene is murR [H]

Identifier: 227080425

GI number: 227080425

Start: 198432

End: 199280

Strand: Reverse

Name: murR [H]

Synonym: VCM66_0192

Alternate gene names: 227080425

Gene position: 199280-198432 (Counterclockwise)

Preceding gene: 227080429

Following gene: 227080420

Centisome position: 6.89

GC content: 53.95

Gene sequence:

>849_bases
ATGTCCGTACTACAACGCATCGTCAGCCGTCGCACCCAACTTTCCGAGAGTGGCCGCCAGATTGGTGATTGGGTTCTCGC
CAATGCGGCGCAGGCGGCAGCAATGACCAGCCAAGATTTGGCCGCGTGGGCCAATGTGAGCCAATCGAGCATAGTCAAAT
TTACCCAACGGCTTGGTTTTAAAGGCTACAGCGAATTTAAACTCGCCCTCACCGAAGAGCTGGGACGCAAACAAGTCATG
GTCAACCAGCCTTTACACAGCAACATCTTGGCCGATGACCCCGTCGCCGTAATTGCCCAAAAACTGGTGCAAACCAAAAC
CGAAGCGATGTTTCACACGACCAATGCCCTGCGTTTGGATGAGTTCAGTGAGGCGATCAGCTGGATTCAGCAAGCGGTGC
GGGTACAGATCATCGGGATTGGTGGCTCAGCGCTGGTCGCCAAAGATCTCGCATTTAAGCTGCTCAAGCTCGGCATTACC
GCGCTCACGGAGCAAGATAGCCACGTGCAGATCGCGACTGCTCGCACCTTACATAGCCAAGATGTGCTGATTGCGATTTC
ATTTTCCGGAGAAAAGCGCGAAATTCTGATTGCAGCACAAGCGGCCAAACAGCAAGGCGCGAAAGTGATTGCCCTAACTA
CACCGAACAAAAATCGCTTACGTGAACTGGCCGATCTGGCGCTGGATACGATTGCCGATGAAACGCAGCACCGCAGCTCT
GCGATTGCTTCGCGTACCGCGCAAAACGTGCTGACCGACCTGATTTTTCTCACCCTCACTCAGCAGCGTGAAACGTCCGC
GCGGCAGTTGATCGATGACATTTCTTCCGACATTCGCCAGATGCGTTGA

Upstream 100 bases:

>100_bases
AAAATAAACGCTCAACCATGAAACCATTGATTGAGAAAGCATGAAGCGTGGCAGGCATTATTCCTACGATGGAATAATTT
ATTCATAAGGAGTGTAAAAA

Downstream 100 bases:

>100_bases
GAGGCAAGCGCCTCTCAACTGAGGGTTTAGCGTGCACGCTGACTGAGTAACAGCAGCAGGAAATAGCTGCCACCAATGAT
TGCCACTAGCGTGCCTGCGG

Product: Putative HTH-type transcriptional regulator yfeT

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSVLQRIVSRRTQLSESGRQIGDWVLANAAQAAAMTSQDLAAWANVSQSSIVKFTQRLGFKGYSEFKLALTEELGRKQVM
VNQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLDEFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGIT
ALTEQDSHVQIATARTLHSQDVLIAISFSGEKREILIAAQAAKQQGAKVIALTTPNKNRLRELADLALDTIADETQHRSS
AIASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR

Sequences:

>Translated_282_residues
MSVLQRIVSRRTQLSESGRQIGDWVLANAAQAAAMTSQDLAAWANVSQSSIVKFTQRLGFKGYSEFKLALTEELGRKQVM
VNQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLDEFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGIT
ALTEQDSHVQIATARTLHSQDVLIAISFSGEKREILIAAQAAKQQGAKVIALTTPNKNRLRELADLALDTIADETQHRSS
AIASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR
>Mature_281_residues
SVLQRIVSRRTQLSESGRQIGDWVLANAAQAAAMTSQDLAAWANVSQSSIVKFTQRLGFKGYSEFKLALTEELGRKQVMV
NQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLDEFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGITA
LTEQDSHVQIATARTLHSQDVLIAISFSGEKREILIAAQAAKQQGAKVIALTTPNKNRLRELADLALDTIADETQHRSSA
IASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=274, Percent_Identity=40.8759124087591, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI87082130, Length=262, Percent_Identity=38.9312977099237, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1788159, Length=282, Percent_Identity=26.241134751773, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082369, Length=252, Percent_Identity=25.3968253968254, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30970; Mature: 30839

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLQRIVSRRTQLSESGRQIGDWVLANAAQAAAMTSQDLAAWANVSQSSIVKFTQRLGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KGYSEFKLALTEELGRKQVMVNQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLD
CCCHHHHHHHHHHCCCCCEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
EFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGITALTEQDSHVQIATARTLHSQ
HHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCC
DVLIAISFSGEKREILIAAQAAKQQGAKVIALTTPNKNRLRELADLALDTIADETQHRSS
CEEEEEEECCCCCEEEEEEHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AIASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVLQRIVSRRTQLSESGRQIGDWVLANAAQAAAMTSQDLAAWANVSQSSIVKFTQRLGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KGYSEFKLALTEELGRKQVMVNQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLD
CCCHHHHHHHHHHCCCCCEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
EFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGITALTEQDSHVQIATARTLHSQ
HHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCC
DVLIAISFSGEKREILIAAQAAKQQGAKVIALTTPNKNRLRELADLALDTIADETQHRSS
CEEEEEEECCCCCEEEEEEHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AIASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA