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The map label for this gene is fabD [H]

Identifier: 226951054

GI number: 226951054

Start: 4112622

End: 4113566

Strand: Reverse

Name: fabD [H]

Synonym: CLM_4093

Alternate gene names: 226951054

Gene position: 4113566-4112622 (Counterclockwise)

Preceding gene: 226951055

Following gene: 226951053

Centisome position: 99.0

GC content: 31.53

Gene sequence:

>945_bases
ATGTCAAAGATAGCTTTTATATTCTCAGGTCAAGGATCTCAATATGTAGGTATGGGTAAGGAGCTATATGAAAATATTCC
TGAGTGTAGAAAAATATTTCATATAGCAGAGAAAGGGTTACAAATACCTTTAACTAAAATATGTTTTGAAGGCCCAAAGG
ATGAAATAGATAAAACAGAAAATACCCAACCAGCAATACTAACCTTTAGTATTGCTGCTATGAAAGCATTAGAAAAGTAT
GGCATAAAGCCAGATGTTACAGCAGGGCTAAGCTTAGGTGAATATTCAGCTTTGGTTTGTAGTAAAGTTATAGATTTTAA
AGAAGCAGTTTCCTTGGTAAGAAAAAGAGGGCAATATATGGAGCATGCGGTACCGAGTGGCGTGGGCACTATGGCAGCTA
TAATAGGTCTTAAAAAGGAAAAGGTTAAGGAAATTTGTGATGGTTTAAAAGAAGTTGGAATAGTTGAAATAGCAAATATT
AATTGCCCAGGGCAGATTGTTATTTCTGGAGAAATAAATGCAGTAGAAAAGGCCTGTGAAATGGCAAAAGAAAAAAGAGC
TTTAAAGTGTGTAAACCTTAGTGTTAGTGGGCCATTTCATAGTAGTATGTTAAAAGAAGCTGGAGAAAATTTATATGAAG
AGTTACAAAAAATACAGTTTAAGTCTATAGAAGTTCCATTTATAACAAATGTAACAGGAGATTTTGTTATAAATACTAGT
GAAATAAAAGATTTATTAAAGAAACAGGTTATGAGTACTGTACTTTGGGAAGGGTCTATAAAAACAATGATAGATTTTGG
GGTAGATACCTTTATAGAAATAGGTCCTTCAAAGGTTTTATCAGGTTTTGTTAAGAAAATAGATAGGAAAGTAAATATAT
TAAATGTAGAAGATATAGATTCCCTTAATAAAACAATAGAAAAATTAAAAACAATAAATAGTTAG

Upstream 100 bases:

>100_bases
TTATAAATAAGGAACAAACTTGTAGTGAAATTATAAATGAAATGTTTAATGAAGCCTATACACTATTAGGTTGTAAATAA
TATTTATTTTGGAGGATATT

Downstream 100 bases:

>100_bases
GAGAGTTGGGTAATAATATGAAATGTTTAGAAGGTAGAACCGCAATAGTAACAGGAGCAAGTAGAGGTATAGGAAGAGCA
ATAGCTAAAAAATTAGCGTC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSKIAFIFSGQGSQYVGMGKELYENIPECRKIFHIAEKGLQIPLTKICFEGPKDEIDKTENTQPAILTFSIAAMKALEKY
GIKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYMEHAVPSGVGTMAAIIGLKKEKVKEICDGLKEVGIVEIANI
NCPGQIVISGEINAVEKACEMAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIQFKSIEVPFITNVTGDFVINTS
EIKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDIDSLNKTIEKLKTINS

Sequences:

>Translated_314_residues
MSKIAFIFSGQGSQYVGMGKELYENIPECRKIFHIAEKGLQIPLTKICFEGPKDEIDKTENTQPAILTFSIAAMKALEKY
GIKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYMEHAVPSGVGTMAAIIGLKKEKVKEICDGLKEVGIVEIANI
NCPGQIVISGEINAVEKACEMAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIQFKSIEVPFITNVTGDFVINTS
EIKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDIDSLNKTIEKLKTINS
>Mature_313_residues
SKIAFIFSGQGSQYVGMGKELYENIPECRKIFHIAEKGLQIPLTKICFEGPKDEIDKTENTQPAILTFSIAAMKALEKYG
IKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYMEHAVPSGVGTMAAIIGLKKEKVKEICDGLKEVGIVEIANIN
CPGQIVISGEINAVEKACEMAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIQFKSIEVPFITNVTGDFVINTSE
IKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDIDSLNKTIEKLKTINS

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=30.2631578947368, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=37.6146788990826, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=42.3611111111111, Blast_Score=222, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=29.3918918918919, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=28.2312925170068, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=32.6732673267327, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34561; Mature: 34430

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIAFIFSGQGSQYVGMGKELYENIPECRKIFHIAEKGLQIPLTKICFEGPKDEIDKTE
CCCEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHCCCC
NTQPAILTFSIAAMKALEKYGIKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYM
CCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHAVPSGVGTMAAIIGLKKEKVKEICDGLKEVGIVEIANINCPGQIVISGEINAVEKACE
HHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHHHHHHH
MAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIQFKSIEVPFITNVTGDFVINTS
HHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEHH
EIKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDID
HHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHCCHHHHHHHHHHHHHCCCEEECHHHHH
SLNKTIEKLKTINS
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SKIAFIFSGQGSQYVGMGKELYENIPECRKIFHIAEKGLQIPLTKICFEGPKDEIDKTE
CCEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHCCCC
NTQPAILTFSIAAMKALEKYGIKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYM
CCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHAVPSGVGTMAAIIGLKKEKVKEICDGLKEVGIVEIANINCPGQIVISGEINAVEKACE
HHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHHHHHHH
MAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIQFKSIEVPFITNVTGDFVINTS
HHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEHH
EIKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDID
HHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHCCHHHHHHHHHHHHHCCCEEECHHHHH
SLNKTIEKLKTINS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]