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The map label for this gene is licH [H]

Identifier: 226950797

GI number: 226950797

Start: 3849897

End: 3851234

Strand: Reverse

Name: licH [H]

Synonym: CLM_3808

Alternate gene names: 226950797

Gene position: 3851234-3849897 (Counterclockwise)

Preceding gene: 226950798

Following gene: 226950796

Centisome position: 92.68

GC content: 31.46

Gene sequence:

>1338_bases
ATGGATAATGGCATAAAAATAGTAACTATAGGTGGGGGATCAAGCTATACACCAGAATTAGTTGAAGGATTTATAAAGAG
GTATAATGAGTTACCAGTTAGGGAATTGTGGTTAGTAGATATAGAGGAAGGAAGAGAAAAGTTACAGATTGTAGGGAATT
TGGCTAAGAGGATGGTAAGAAAAGCAGGAATACCAATGGAAATACATTTAACATTAGATAGGAAAAAAGCATTAAAAGAT
GCTGATTTTGTAACAACACAAATAAGAGTAGGATTTTTAGATGCAAGAATAAAAGATGAAAAAATTCCTTTAAATCATGG
TGTTATAGGGCAAGAAACTAATGGGGCAGGAGGAATGTTTGAAGCATTAAGGACAATCCCTGTAATTCTAGATATAGATA
AGGATATGAGTAAATTGTGCCCTAATGCTTGGATGATAAATTTTACTAATCCAGCAGGTATGGTTACGGAAGCATTATTA
AGATATGGAAAAAATAAAAGAGTTATAGGTCTTTGTAATGTTCCTATAGGTATGGAGAAGGCAGCTGCAAAAGTTTTAGA
GATTGAACATAAGAGACTAAGAATGGATTTTGTAGGATTGAACCATATGGTGTTCGGAAAAGAAGTATATGTAGATGGAA
TAAAGGTTACAGATAAATTAATTAACTTATTGGCTGATGGAAATATAGGACAAATAGTCAAAAATGTATCGGACTTTACA
TGGAATAAAGATTTTATAAAAGCTTTAGGAATGATGCCATGTCCATATCACAAATATTATTTTCAAACAAAAGATATGCT
AAAAGAAGAACTAGAACAATTTTCTAAGGGTGAAACTAGAGCCGAGGTTGTTAAAAAAGTAGAAGAGGAATTATTTAAAC
TTTATAAAGATGAAAATTTGGATATTAAACCTCCTGAATTAGAGAAAAGAGGAGGAGCTTATTACAGTGATGCAGCGTGC
AGACTAATATGTTCAATATACAATGATAAAAAAGATATTCAACCAGTAAATATAAGAAATAATGGAGCTATAACAGGAAT
ACCTAATGAATCTGCTGTAGAAATTTCATGTATGATAACAAAAGATGGTCCTAAACCAATAACAGTAGGAGATTTGCCAA
TAAGTATAAATGGATTGATACAACAGATAAAAGCTTTTGAGAGGCTGGTGGTAGATTCAGCAGTTTTTGGTGATTATCAT
AAGGCGATATTAGCATTGACTGTAAATCCTTTAGTTCAATCGGATAAACTTGCAAAGACATTGGTAGATGAACTTATGAT
AGCTCATAAAGATTATTTACCACAGTTTAAAGAACTTATAGAAGAAAATTTTAAATAA

Upstream 100 bases:

>100_bases
TTATACAACACATGAACAAGTGGATTTTGCAATAAAAAGGTATTGGCATGATGTTTGCTATATATAATAGTGTACATATA
AAACACTGGGGGTGTGTTCT

Downstream 100 bases:

>100_bases
CGATCATTTTAAAATAGATTACTATTATTAATTATTTATAAATATATAAAAAATATGTATATAAAAAGGGAGGGTTAGAA
ATGAAAAAGTTCTTTGACTG

Product: glycosyl hydrolase, family 4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MDNGIKIVTIGGGSSYTPELVEGFIKRYNELPVRELWLVDIEEGREKLQIVGNLAKRMVRKAGIPMEIHLTLDRKKALKD
ADFVTTQIRVGFLDARIKDEKIPLNHGVIGQETNGAGGMFEALRTIPVILDIDKDMSKLCPNAWMINFTNPAGMVTEALL
RYGKNKRVIGLCNVPIGMEKAAAKVLEIEHKRLRMDFVGLNHMVFGKEVYVDGIKVTDKLINLLADGNIGQIVKNVSDFT
WNKDFIKALGMMPCPYHKYYFQTKDMLKEELEQFSKGETRAEVVKKVEEELFKLYKDENLDIKPPELEKRGGAYYSDAAC
RLICSIYNDKKDIQPVNIRNNGAITGIPNESAVEISCMITKDGPKPITVGDLPISINGLIQQIKAFERLVVDSAVFGDYH
KAILALTVNPLVQSDKLAKTLVDELMIAHKDYLPQFKELIEENFK

Sequences:

>Translated_445_residues
MDNGIKIVTIGGGSSYTPELVEGFIKRYNELPVRELWLVDIEEGREKLQIVGNLAKRMVRKAGIPMEIHLTLDRKKALKD
ADFVTTQIRVGFLDARIKDEKIPLNHGVIGQETNGAGGMFEALRTIPVILDIDKDMSKLCPNAWMINFTNPAGMVTEALL
RYGKNKRVIGLCNVPIGMEKAAAKVLEIEHKRLRMDFVGLNHMVFGKEVYVDGIKVTDKLINLLADGNIGQIVKNVSDFT
WNKDFIKALGMMPCPYHKYYFQTKDMLKEELEQFSKGETRAEVVKKVEEELFKLYKDENLDIKPPELEKRGGAYYSDAAC
RLICSIYNDKKDIQPVNIRNNGAITGIPNESAVEISCMITKDGPKPITVGDLPISINGLIQQIKAFERLVVDSAVFGDYH
KAILALTVNPLVQSDKLAKTLVDELMIAHKDYLPQFKELIEENFK
>Mature_445_residues
MDNGIKIVTIGGGSSYTPELVEGFIKRYNELPVRELWLVDIEEGREKLQIVGNLAKRMVRKAGIPMEIHLTLDRKKALKD
ADFVTTQIRVGFLDARIKDEKIPLNHGVIGQETNGAGGMFEALRTIPVILDIDKDMSKLCPNAWMINFTNPAGMVTEALL
RYGKNKRVIGLCNVPIGMEKAAAKVLEIEHKRLRMDFVGLNHMVFGKEVYVDGIKVTDKLINLLADGNIGQIVKNVSDFT
WNKDFIKALGMMPCPYHKYYFQTKDMLKEELEQFSKGETRAEVVKKVEEELFKLYKDENLDIKPPELEKRGGAYYSDAAC
RLICSIYNDKKDIQPVNIRNNGAITGIPNESAVEISCMITKDGPKPITVGDLPISINGLIQQIKAFERLVVDSAVFGDYH
KAILALTVNPLVQSDKLAKTLVDELMIAHKDYLPQFKELIEENFK

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=445, Percent_Identity=52.5842696629213, Blast_Score=473, Evalue=1e-135,
Organism=Escherichia coli, GI1790560, Length=465, Percent_Identity=27.5268817204301, Blast_Score=148, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 50102; Mature: 50102

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNGIKIVTIGGGSSYTPELVEGFIKRYNELPVRELWLVDIEEGREKLQIVGNLAKRMVR
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHH
KAGIPMEIHLTLDRKKALKDADFVTTQIRVGFLDARIKDEKIPLNHGVIGQETNGAGGMF
HCCCCEEEEEEECHHHHHCCCHHEEEEEEEEEEECEECCCCCCCCCCCCCCCCCCCCHHH
EALRTIPVILDIDKDMSKLCPNAWMINFTNPAGMVTEALLRYGKNKRVIGLCNVPIGMEK
HHHHHCCEEEECCCCHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHH
AAAKVLEIEHKRLRMDFVGLNHMVFGKEVYVDGIKVTDKLINLLADGNIGQIVKNVSDFT
HHHHHHHHHHHHHEEHEECCCEEEECCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCC
WNKDFIKALGMMPCPYHKYYFQTKDMLKEELEQFSKGETRAEVVKKVEEELFKLYKDENL
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
DIKPPELEKRGGAYYSDAACRLICSIYNDKKDIQPVNIRNNGAITGIPNESAVEISCMIT
CCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCEEEEEEEEE
KDGPKPITVGDLPISINGLIQQIKAFERLVVDSAVFGDYHKAILALTVNPLVQSDKLAKT
CCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHH
LVDELMIAHKDYLPQFKELIEENFK
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDNGIKIVTIGGGSSYTPELVEGFIKRYNELPVRELWLVDIEEGREKLQIVGNLAKRMVR
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHH
KAGIPMEIHLTLDRKKALKDADFVTTQIRVGFLDARIKDEKIPLNHGVIGQETNGAGGMF
HCCCCEEEEEEECHHHHHCCCHHEEEEEEEEEEECEECCCCCCCCCCCCCCCCCCCCHHH
EALRTIPVILDIDKDMSKLCPNAWMINFTNPAGMVTEALLRYGKNKRVIGLCNVPIGMEK
HHHHHCCEEEECCCCHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHH
AAAKVLEIEHKRLRMDFVGLNHMVFGKEVYVDGIKVTDKLINLLADGNIGQIVKNVSDFT
HHHHHHHHHHHHHEEHEECCCEEEECCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCC
WNKDFIKALGMMPCPYHKYYFQTKDMLKEELEQFSKGETRAEVVKKVEEELFKLYKDENL
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
DIKPPELEKRGGAYYSDAACRLICSIYNDKKDIQPVNIRNNGAITGIPNESAVEISCMIT
CCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCEEEEEEEEE
KDGPKPITVGDLPISINGLIQQIKAFERLVVDSAVFGDYHKAILALTVNPLVQSDKLAKT
CCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHH
LVDELMIAHKDYLPQFKELIEENFK
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]