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The map label for this gene is patA [H]

Identifier: 226950584

GI number: 226950584

Start: 3599009

End: 3600172

Strand: Reverse

Name: patA [H]

Synonym: CLM_3567

Alternate gene names: 226950584

Gene position: 3600172-3599009 (Counterclockwise)

Preceding gene: 226950586

Following gene: 226950580

Centisome position: 86.64

GC content: 27.75

Gene sequence:

>1164_bases
ATGGATTATATAAAGACTGAAGAAATTATTTCGGAAAAAGTTAAAAATATAGAAATTTCCGGTATAAGGAGGTTTTTTAA
CAAAGTTTCAAATTATAAAGATGTTATTTCCTTAACTTTAGGGCAACCAGACTTTAAGCTTCCAAGTAGAATAAAAGATG
AATTAATAAATTCTATACAAGAAGATAAAACAACCTATACATCTAATGCAGGATTAAAAGAGTTAAGATTAGAGATAGCA
AGATATCTTAAAACTATGAATATTAATTATAATTCAGAAGAAATATGCATAACCGTAGGTGGTAGTGAAGGGTTGATGTG
TGTATTTTTCACATTACTAAATGAGGGAGACAAAGTTTTAATACCAACACCTGCATATCCTGCTTATGAAAGCTGTGTAA
AATTATTAGGTGGACAAATATTAAATTATAAATTAAAAAATGATTTTTCTATAGATTTTTCAGATTTAGAAAATATAATA
GAAAAAGAAAAACCTAAGGTTATGGTATTATCTTATCCATCTAATCCCACAGGAGCTATACTTTCTAAGGAAGAAAGTTA
TAAGCTATATAATATAATAAAAGAAAACAATATCATAGTAATAAGTGATGAAATATACAGTTCCTTATGTTTTGAAGAGA
AATATTATTCTATAGCTCAGTATGGAGATATAAAAGACAAGGTTATATTAGTTAGTGGATTTTCAAAAATGTTTTCAATG
ACTGGTCTTAGAATAGGGTATGTTTGTGCAAAGGATGAATTTATAAATTCTATAATAAAAGTTCATCAATATAATGTATC
TTGTGCACCTTCTATATGTCAATGGGGAGCTTATGCAGGATTAAAATACTGTATGGAAGATGTAGCTTATATGAAAGAGG
AATTTATAAAAAGAAGAGATTTTGTATATAATAGACTAAAATACATGGGAATAGATACATATCTTCCTAAGGGAGCTTTT
TATATATTTCCTTCCATAAAAAAATATAATATGACTAGTGAAGAATTTTGTGAAAGACTTTTGAAGGAAGCTAAAGTGGC
TATAGTTCCTGGCTCAGCCTTTGGAGAAATGGGAGAGGGATATATTAGAATATCTTATGCCTATAGCATGGAAGAATTAA
ATGAAGCACTAAACAGAATGGAAAAATGGCTTAATATTCTTTAA

Upstream 100 bases:

>100_bases
TGGAGATTTAATAAAATATATTGGTTCTAGGATCGTAAAAAATATAAAGGGAAAGGAGAAGTTATGGTTTATTAACATTC
CCATAACATGATAATATTTT

Downstream 100 bases:

>100_bases
AGATTGAGAATTAAACTTTACCACACAGGAAATTTTCTTTAAATATTTATACTAACTTCGGCCTATTAAAAAGAGGGATA
TGTGGCGTAAAAGGCATTGG

Product: class I/II aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQEDKTTYTSNAGLKELRLEIA
RYLKTMNINYNSEEICITVGGSEGLMCVFFTLLNEGDKVLIPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENII
EKEKPKVMVLSYPSNPTGAILSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
TGLRIGYVCAKDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRDFVYNRLKYMGIDTYLPKGAF
YIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEGYIRISYAYSMEELNEALNRMEKWLNIL

Sequences:

>Translated_387_residues
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQEDKTTYTSNAGLKELRLEIA
RYLKTMNINYNSEEICITVGGSEGLMCVFFTLLNEGDKVLIPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENII
EKEKPKVMVLSYPSNPTGAILSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
TGLRIGYVCAKDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRDFVYNRLKYMGIDTYLPKGAF
YIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEGYIRISYAYSMEELNEALNRMEKWLNIL
>Mature_387_residues
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQEDKTTYTSNAGLKELRLEIA
RYLKTMNINYNSEEICITVGGSEGLMCVFFTLLNEGDKVLIPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENII
EKEKPKVMVLSYPSNPTGAILSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
TGLRIGYVCAKDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRDFVYNRLKYMGIDTYLPKGAF
YIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEGYIRISYAYSMEELNEALNRMEKWLNIL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=402, Percent_Identity=22.636815920398, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI169881279, Length=402, Percent_Identity=22.636815920398, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI56713254, Length=398, Percent_Identity=24.3718592964824, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI56713256, Length=398, Percent_Identity=24.3718592964824, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=23.4042553191489, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI7705897, Length=347, Percent_Identity=23.6311239193084, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI33469970, Length=347, Percent_Identity=23.6311239193084, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI169881281, Length=313, Percent_Identity=21.0862619808307, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI215599424, Length=371, Percent_Identity=23.4501347708895, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI19263340, Length=371, Percent_Identity=23.4501347708895, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI187936925, Length=394, Percent_Identity=23.8578680203046, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI14211921, Length=394, Percent_Identity=23.8578680203046, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI149944424, Length=361, Percent_Identity=23.2686980609418, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788722, Length=360, Percent_Identity=29.1666666666667, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1786816, Length=365, Percent_Identity=24.9315068493151, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788627, Length=374, Percent_Identity=27.0053475935829, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1790797, Length=391, Percent_Identity=23.0179028132992, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787909, Length=275, Percent_Identity=22.1818181818182, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787710, Length=181, Percent_Identity=28.7292817679558, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788332, Length=170, Percent_Identity=24.1176470588235, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=364, Percent_Identity=26.3736263736264, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=364, Percent_Identity=26.3736263736264, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=25.5376344086022, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=367, Percent_Identity=25.3405994550409, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71981209, Length=367, Percent_Identity=25.3405994550409, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=213, Percent_Identity=27.2300469483568, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=329, Percent_Identity=24.3161094224924, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323118, Length=371, Percent_Identity=26.9541778975741, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320317, Length=364, Percent_Identity=25.5494505494505, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=25.0645994832041, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=25.0645994832041, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=25.0645994832041, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=25.0645994832041, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24641770, Length=368, Percent_Identity=24.7282608695652, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641760, Length=368, Percent_Identity=24.7282608695652, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641768, Length=368, Percent_Identity=24.7282608695652, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641766, Length=368, Percent_Identity=24.7282608695652, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641764, Length=368, Percent_Identity=24.7282608695652, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45551451, Length=368, Percent_Identity=24.7282608695652, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859735, Length=383, Percent_Identity=22.1932114882507, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 44504; Mature: 44504

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQ
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHEEEECCCCCCCCHHHHHHHHHHHHH
EDKTTYTSNAGLKELRLEIARYLKTMNINYNSEEICITVGGSEGLMCVFFTLLNEGDKVL
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEE
IPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENIIEKEKPKVMVLSYPSNPTGAI
EECCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCE
LSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
ECCCCCCHHHHEEECCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHH
TGLRIGYVCAKDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRD
CCCEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVYNRLKYMGIDTYLPKGAFYIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEG
HHHHHHHHCCCHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHCCCCC
YIRISYAYSMEELNEALNRMEKWLNIL
EEEEEEEECHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQ
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHEEEECCCCCCCCHHHHHHHHHHHHH
EDKTTYTSNAGLKELRLEIARYLKTMNINYNSEEICITVGGSEGLMCVFFTLLNEGDKVL
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEE
IPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENIIEKEKPKVMVLSYPSNPTGAI
EECCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCE
LSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
ECCCCCCHHHHEEECCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHH
TGLRIGYVCAKDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRD
CCCEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVYNRLKYMGIDTYLPKGAFYIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEG
HHHHHHHHCCCHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHCCCCC
YIRISYAYSMEELNEALNRMEKWLNIL
EEEEEEEECHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]