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The map label for this gene is resE [H]

Identifier: 226950175

GI number: 226950175

Start: 3130453

End: 3132561

Strand: Reverse

Name: resE [H]

Synonym: CLM_3129

Alternate gene names: 226950175

Gene position: 3132561-3130453 (Counterclockwise)

Preceding gene: 226950176

Following gene: 226950173

Centisome position: 75.39

GC content: 23.61

Gene sequence:

>2109_bases
ATGGAACCAATAGGAAGTGTTTTTTTGGAAGATAAAAGTACAATAAAAAGTATAATGGATAGCATTCCTTATTCATGTTA
TATTGTAAACGATGAATATGAATTGCTTTATGTAAATAGTGTAGCTCTAAAGTTAAGCAAAGAGCTAAAAAGAAAATATA
GTTCTAAGCTAAGGCCTGGAGAAGAAAAAACATTGATGAATTGTTTAGATGAATACGAAATAAATTTTATCGATGGTGAA
ACTGTTACAGAAAAAAACTTTCCTGTTTTTATAGCTCTTAAAGAACAAAAGGAGATAAAAGAAATTCCATTAATATTTAC
AAAGAATAATTATGAAAAGGTGTGTTTTAGTTTAACTGTAATACCTATAAATTTAGAAGGAACCAAAAAAGGAGCTTTAG
TAAATTTAATGGATATTACTCAAGAGCGTATCTATAAAGAAACCATAGAAAAGGGTAAGGAAGAGATTTTAAATATTTCA
AAACAAATAAAAAATAAGAGTGAGATTATAGACATATTAAGAAAAAAAGAATTAGATTATATAAAATATCTTAATAATGT
AATTAATAATATATCTGAAGGAATATTGGTTTTTGATAAGTATTCAAAATTAATTTTATGGAATAAAGCTATTGAACAAA
TAGGTGAAATGAAAATTAAAAAAATATTGGATATTAAAGAAATAATTAATGAGTATGATATATACATACTAGATGATCAT
AAAAATATGAAATATAAAATAAAAAAGATGAATCCAGATTATAATAGAAGTGTAAAAGACTTATTATTGAAATTAGTAAA
GAAAGATACTAATAAGATTAAATATATAGAGTATAACAGTAATCCCATTATGGATGAAAATAATGAGATACTTTATACTA
TATCAAGTATAAAGAATGTTACAGATTTAATAGAAAGTCAAATAATATCTGAAGAGAGGGCAGAATTTATAAAATATGTA
GTAGATTGTATAGAGCTACCCTTAGCAGTATTAGACTATCCCGATTTAACATATAGATTAGTTAATGAAAGATATGAAGA
GTTAGTAGAACGATTACATACTAAAAAAATAAAGGGAAATTTACTTGGAAATACAGTGGAGAATATTTTTAGAAAAGAAG
AATTTAAAGAGCAGTTAGAAGTATTACAGAAAATGAAAGATGGAACTATTAAAGAGTATACATTTTCTCCTAAAAAATTT
ATTCTACAGTCAGGAGAAGAAAGATTTTTTAAAGTAAGATATATTTATCATGAAACTAAAAATAAAAAAAGAGTTCACAT
ACATGGTTCTGATGTAACAGAAGAGCTTAAAAGTAATTTGGAACTAGAAAAGGTGAATAAACTTAAAGATGAGTTTTTTA
CTATAATATCTCATGAATTAAGAACTCCATTAACCATAATATATTCTTCATTGCAATTAGCTTATGATATTTATCCAGAA
GATATAAACTTAAATATCGATAAGATTTTAAAAAGAATAAATCAAAATACAGCTAGACTTTTAAAGCTTATAAATAATAT
ATTAGATATATCAAAAGCAGAAGCAGGATTTTTAACTTTAAATAATGAATATTTTGATATAGTATTGGAAACAGAAAATA
TAGTTAATTCAATAACAAATTATGCTAATTCTAAAAATATAAATTTAATATTTGATACTACGAAAGAAGAAGAAGAGGTT
TGGATTGATAAAGATAAATATGAAAGAATATTATTAAATTTATTATCTAATGCTGTAAAATTCACGCCAGAAAACAAATC
TATATATGTTACTCTTAAAATATATAAAAATAATTTTAAATTAATAGTAAAAGATGAAGGAAGAGGAATACCTAAAGAAA
AAATAGATTGTATTTTTAACAGATTTGCTCAAGTTAATAGTTCATTATCAAGAAGTGCAGAAGGGACAGGTATAGGACTT
TCATTAGTTAAGAAAATTGTGGATCTCATGGATGGAGAAATAAAGGTATATAGTATTTTGGGGAAGGGAACTACATTTAC
TGTTAAAATAAATAAAAATATGAATAAATGTTATGAAAAGATAAAGAAAGCTGTTATACACAATGATATTTCTAAAAAAA
TACATATAGAGTTTTCAGACATAAACTAG

Upstream 100 bases:

>100_bases
AAATTTTAAAAGCTGTTAAGTCGTAATTTCCTTAGAAGTTGACTAAGGCTACAGAAAAAGAGTAAACTATATAAAGCAAT
GTATATATTAGGGGGGAAAT

Downstream 100 bases:

>100_bases
AAAATATATAAAACCCTATTTAGGTAAATAAAATTTACAATTAAATAGGGCTTTTATTGTTAATGCATAGTAGAAACCTA
AACAAATATTGTGAATTTTA

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 702

Protein sequence:

>702_residues
MEPIGSVFLEDKSTIKSIMDSIPYSCYIVNDEYELLYVNSVALKLSKELKRKYSSKLRPGEEKTLMNCLDEYEINFIDGE
TVTEKNFPVFIALKEQKEIKEIPLIFTKNNYEKVCFSLTVIPINLEGTKKGALVNLMDITQERIYKETIEKGKEEILNIS
KQIKNKSEIIDILRKKELDYIKYLNNVINNISEGILVFDKYSKLILWNKAIEQIGEMKIKKILDIKEIINEYDIYILDDH
KNMKYKIKKMNPDYNRSVKDLLLKLVKKDTNKIKYIEYNSNPIMDENNEILYTISSIKNVTDLIESQIISEERAEFIKYV
VDCIELPLAVLDYPDLTYRLVNERYEELVERLHTKKIKGNLLGNTVENIFRKEEFKEQLEVLQKMKDGTIKEYTFSPKKF
ILQSGEERFFKVRYIYHETKNKKRVHIHGSDVTEELKSNLELEKVNKLKDEFFTIISHELRTPLTIIYSSLQLAYDIYPE
DINLNIDKILKRINQNTARLLKLINNILDISKAEAGFLTLNNEYFDIVLETENIVNSITNYANSKNINLIFDTTKEEEEV
WIDKDKYERILLNLLSNAVKFTPENKSIYVTLKIYKNNFKLIVKDEGRGIPKEKIDCIFNRFAQVNSSLSRSAEGTGIGL
SLVKKIVDLMDGEIKVYSILGKGTTFTVKINKNMNKCYEKIKKAVIHNDISKKIHIEFSDIN

Sequences:

>Translated_702_residues
MEPIGSVFLEDKSTIKSIMDSIPYSCYIVNDEYELLYVNSVALKLSKELKRKYSSKLRPGEEKTLMNCLDEYEINFIDGE
TVTEKNFPVFIALKEQKEIKEIPLIFTKNNYEKVCFSLTVIPINLEGTKKGALVNLMDITQERIYKETIEKGKEEILNIS
KQIKNKSEIIDILRKKELDYIKYLNNVINNISEGILVFDKYSKLILWNKAIEQIGEMKIKKILDIKEIINEYDIYILDDH
KNMKYKIKKMNPDYNRSVKDLLLKLVKKDTNKIKYIEYNSNPIMDENNEILYTISSIKNVTDLIESQIISEERAEFIKYV
VDCIELPLAVLDYPDLTYRLVNERYEELVERLHTKKIKGNLLGNTVENIFRKEEFKEQLEVLQKMKDGTIKEYTFSPKKF
ILQSGEERFFKVRYIYHETKNKKRVHIHGSDVTEELKSNLELEKVNKLKDEFFTIISHELRTPLTIIYSSLQLAYDIYPE
DINLNIDKILKRINQNTARLLKLINNILDISKAEAGFLTLNNEYFDIVLETENIVNSITNYANSKNINLIFDTTKEEEEV
WIDKDKYERILLNLLSNAVKFTPENKSIYVTLKIYKNNFKLIVKDEGRGIPKEKIDCIFNRFAQVNSSLSRSAEGTGIGL
SLVKKIVDLMDGEIKVYSILGKGTTFTVKINKNMNKCYEKIKKAVIHNDISKKIHIEFSDIN
>Mature_702_residues
MEPIGSVFLEDKSTIKSIMDSIPYSCYIVNDEYELLYVNSVALKLSKELKRKYSSKLRPGEEKTLMNCLDEYEINFIDGE
TVTEKNFPVFIALKEQKEIKEIPLIFTKNNYEKVCFSLTVIPINLEGTKKGALVNLMDITQERIYKETIEKGKEEILNIS
KQIKNKSEIIDILRKKELDYIKYLNNVINNISEGILVFDKYSKLILWNKAIEQIGEMKIKKILDIKEIINEYDIYILDDH
KNMKYKIKKMNPDYNRSVKDLLLKLVKKDTNKIKYIEYNSNPIMDENNEILYTISSIKNVTDLIESQIISEERAEFIKYV
VDCIELPLAVLDYPDLTYRLVNERYEELVERLHTKKIKGNLLGNTVENIFRKEEFKEQLEVLQKMKDGTIKEYTFSPKKF
ILQSGEERFFKVRYIYHETKNKKRVHIHGSDVTEELKSNLELEKVNKLKDEFFTIISHELRTPLTIIYSSLQLAYDIYPE
DINLNIDKILKRINQNTARLLKLINNILDISKAEAGFLTLNNEYFDIVLETENIVNSITNYANSKNINLIFDTTKEEEEV
WIDKDKYERILLNLLSNAVKFTPENKSIYVTLKIYKNNFKLIVKDEGRGIPKEKIDCIFNRFAQVNSSLSRSAEGTGIGL
SLVKKIVDLMDGEIKVYSILGKGTTFTVKINKNMNKCYEKIKKAVIHNDISKKIHIEFSDIN

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=274, Percent_Identity=31.7518248175182, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=32.4786324786325, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789149, Length=280, Percent_Identity=31.0714285714286, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788713, Length=262, Percent_Identity=33.969465648855, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786600, Length=313, Percent_Identity=27.7955271565495, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=27.6595744680851, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=29.5081967213115, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=27.0742358078603, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=27.6018099547511, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=24.7863247863248, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790861, Length=257, Percent_Identity=24.124513618677, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788549, Length=273, Percent_Identity=24.5421245421245, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787894, Length=212, Percent_Identity=25.9433962264151, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790551, Length=227, Percent_Identity=22.4669603524229, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=23.6842105263158, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=236, Percent_Identity=25.4237288135593, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82125; Mature: 82125

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIGSVFLEDKSTIKSIMDSIPYSCYIVNDEYELLYVNSVALKLSKELKRKYSSKLRPG
CCCCCCCEECCHHHHHHHHHCCCCEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHCCCCC
EEKTLMNCLDEYEINFIDGETVTEKNFPVFIALKEQKEIKEIPLIFTKNNYEKVCFSLTV
HHHHHHHHHHHCCEEEECCCEEECCCCCEEEEECCCCCHHHCCEEEECCCCEEEEEEEEE
IPINLEGTKKGALVNLMDITQERIYKETIEKGKEEILNISKQIKNKSEIIDILRKKELDY
EEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHH
IKYLNNVINNISEGILVFDKYSKLILWNKAIEQIGEMKIKKILDIKEIINEYDIYILDDH
HHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
KNMKYKIKKMNPDYNRSVKDLLLKLVKKDTNKIKYIEYNSNPIMDENNEILYTISSIKNV
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHH
TDLIESQIISEERAEFIKYVVDCIELPLAVLDYPDLTYRLVNERYEELVERLHTKKIKGN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
LLGNTVENIFRKEEFKEQLEVLQKMKDGTIKEYTFSPKKFILQSGEERFFKVRYIYHETK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCCCEEEEEEEEEECC
NKKRVHIHGSDVTEELKSNLELEKVNKLKDEFFTIISHELRTPLTIIYSSLQLAYDIYPE
CCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCC
DINLNIDKILKRINQNTARLLKLINNILDISKAEAGFLTLNNEYFDIVLETENIVNSITN
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECHHHHHHHHH
YANSKNINLIFDTTKEEEEVWIDKDKYERILLNLLSNAVKFTPENKSIYVTLKIYKNNFK
HCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECCCE
LIVKDEGRGIPKEKIDCIFNRFAQVNSSLSRSAEGTGIGLSLVKKIVDLMDGEIKVYSIL
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEE
GKGTTFTVKINKNMNKCYEKIKKAVIHNDISKKIHIEFSDIN
CCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure
MEPIGSVFLEDKSTIKSIMDSIPYSCYIVNDEYELLYVNSVALKLSKELKRKYSSKLRPG
CCCCCCCEECCHHHHHHHHHCCCCEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHCCCCC
EEKTLMNCLDEYEINFIDGETVTEKNFPVFIALKEQKEIKEIPLIFTKNNYEKVCFSLTV
HHHHHHHHHHHCCEEEECCCEEECCCCCEEEEECCCCCHHHCCEEEECCCCEEEEEEEEE
IPINLEGTKKGALVNLMDITQERIYKETIEKGKEEILNISKQIKNKSEIIDILRKKELDY
EEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHH
IKYLNNVINNISEGILVFDKYSKLILWNKAIEQIGEMKIKKILDIKEIINEYDIYILDDH
HHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
KNMKYKIKKMNPDYNRSVKDLLLKLVKKDTNKIKYIEYNSNPIMDENNEILYTISSIKNV
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHH
TDLIESQIISEERAEFIKYVVDCIELPLAVLDYPDLTYRLVNERYEELVERLHTKKIKGN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
LLGNTVENIFRKEEFKEQLEVLQKMKDGTIKEYTFSPKKFILQSGEERFFKVRYIYHETK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCCCEEEEEEEEEECC
NKKRVHIHGSDVTEELKSNLELEKVNKLKDEFFTIISHELRTPLTIIYSSLQLAYDIYPE
CCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCC
DINLNIDKILKRINQNTARLLKLINNILDISKAEAGFLTLNNEYFDIVLETENIVNSITN
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECHHHHHHHHH
YANSKNINLIFDTTKEEEEVWIDKDKYERILLNLLSNAVKFTPENKSIYVTLKIYKNNFK
HCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECCCE
LIVKDEGRGIPKEKIDCIFNRFAQVNSSLSRSAEGTGIGLSLVKKIVDLMDGEIKVYSIL
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEE
GKGTTFTVKINKNMNKCYEKIKKAVIHNDISKKIHIEFSDIN
CCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]