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The map label for this gene is engA [H]

Identifier: 226949875

GI number: 226949875

Start: 2832804

End: 2834123

Strand: Reverse

Name: engA [H]

Synonym: CLM_2824

Alternate gene names: 226949875

Gene position: 2834123-2832804 (Counterclockwise)

Preceding gene: 226949876

Following gene: 226949874

Centisome position: 68.21

GC content: 30.76

Gene sequence:

>1320_bases
ATGGGAAAACCTATAGTTGCAATAGTAGGAAGACCTAATGTAGGTAAATCTACACTATTCAATAAATTAGCAGGAAAAAG
GATAGCTATAGTACAAGATACACCAGGGGTGACAAGAGACAGAATTTATGCAGAGGCAGAATGGTTAAATTACAAATTTA
CAATGATAGATACAGGTGGTATAGAACCAAAAAGTGAGGATATAATAGTATCTCAAATGAGAAGACAGGCGCAAATAGCT
ATAGAAATGGCTAATGTAATAATATTTTTAGTAGATGGAAAAGAAGGATTAGCACCAGCAGACGAAGAAGTGGCACAAAT
GCTTAGAAAAAGTAAGAAACCTGTAGTGCTTGTCGTAAATAAAATCGATAAATTGAAAGATGAGAACAATGCTTATGAGT
TTTATAATCTAGGTATAGGAGATCCTGTAACCATATCTTCATCACAGGCATTAGGCTTAGGTGATATGCTAGATAGAGTT
GTAGAATATTTTAAAGATGATGAATCAGATGGAGAAGATGATGAGAGAATAAATATAGCTTTTATAGGTAAACCCAATGT
AGGGAAATCTTCTCTTATAAATAAATTACTAGGCGAAGAAAGACTTATAGTAAGTGATATACCAGGAACCACCAGGGATT
CAATAGATAGTTATGTAGATACAGAATTTGGTGAGTTTACTTTAATAGATACAGCAGGATTAAGACGTAAGAGTAAAGTA
AAGGAAGAAATAGAAAGATATTCTGTAATAAGAACCTATGCGTCTATAGAAAGAGCAGATGTATGTATACTTATGATAGA
TGCTACAGAGGGTATATCTGAGCAGGATCAGAAGATAATAGGATATGCTCATGATATAAATAAAGCTATTTTAGTTATAG
TTAATAAGTGGGATCTAGTTGAAAAAGACGATAAGACTATGGATAAATTTAAAAAAGAGTTAAAAGTTAATTTATCCTTC
ATGCCTTATGCAAAATATTTATTTATATCTGCTAAAACAGGCCAAAGGGTTGTAAAAGTTTTACAAACTGCTAAAGAATG
TTATGATAATTATACTAAGAGAGTAAAAACAGGAGTTTTAAATGATGTAATAAGTCAAGCTATTATGATGAAAGAGCCTC
CTATAGTAGGAACAAAAAGATTAAAAATTTACTATGTAACTCAAATAGGAACAAAACCACCAACTTTTATTTTCTTTGTA
AATGATCCAGCTTGCATACATTTCTCTTATCAAAGATATTTAGAAAATCAATTAAGAGAAAATTTTGATTTCCAAGGTAC
AGGAATAAAATTAGAGTTTAGAGAAAGAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
AAGAATTAAGCAATAGTTTAAAAAGAGAAATTTTAGTATGCGATTATACAGGAGAAGACTTAATAGATATAATAAATGAA
CATAGCAAGGAGGAATAAAA

Downstream 100 bases:

>100_bases
ATTTAAAGATATCCTATAGCTACTGCCACTGGAACTTATTATATAGAGAGTTTTAAGTGGCAGTGAATGCATAGGAATTT
TTAATATAAACTTATTTCTT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVQDTPGVTRDRIYAEAEWLNYKFTMIDTGGIEPKSEDIIVSQMRRQAQIA
IEMANVIIFLVDGKEGLAPADEEVAQMLRKSKKPVVLVVNKIDKLKDENNAYEFYNLGIGDPVTISSSQALGLGDMLDRV
VEYFKDDESDGEDDERINIAFIGKPNVGKSSLINKLLGEERLIVSDIPGTTRDSIDSYVDTEFGEFTLIDTAGLRRKSKV
KEEIERYSVIRTYASIERADVCILMIDATEGISEQDQKIIGYAHDINKAILVIVNKWDLVEKDDKTMDKFKKELKVNLSF
MPYAKYLFISAKTGQRVVKVLQTAKECYDNYTKRVKTGVLNDVISQAIMMKEPPIVGTKRLKIYYVTQIGTKPPTFIFFV
NDPACIHFSYQRYLENQLRENFDFQGTGIKLEFRERKEK

Sequences:

>Translated_439_residues
MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVQDTPGVTRDRIYAEAEWLNYKFTMIDTGGIEPKSEDIIVSQMRRQAQIA
IEMANVIIFLVDGKEGLAPADEEVAQMLRKSKKPVVLVVNKIDKLKDENNAYEFYNLGIGDPVTISSSQALGLGDMLDRV
VEYFKDDESDGEDDERINIAFIGKPNVGKSSLINKLLGEERLIVSDIPGTTRDSIDSYVDTEFGEFTLIDTAGLRRKSKV
KEEIERYSVIRTYASIERADVCILMIDATEGISEQDQKIIGYAHDINKAILVIVNKWDLVEKDDKTMDKFKKELKVNLSF
MPYAKYLFISAKTGQRVVKVLQTAKECYDNYTKRVKTGVLNDVISQAIMMKEPPIVGTKRLKIYYVTQIGTKPPTFIFFV
NDPACIHFSYQRYLENQLRENFDFQGTGIKLEFRERKEK
>Mature_438_residues
GKPIVAIVGRPNVGKSTLFNKLAGKRIAIVQDTPGVTRDRIYAEAEWLNYKFTMIDTGGIEPKSEDIIVSQMRRQAQIAI
EMANVIIFLVDGKEGLAPADEEVAQMLRKSKKPVVLVVNKIDKLKDENNAYEFYNLGIGDPVTISSSQALGLGDMLDRVV
EYFKDDESDGEDDERINIAFIGKPNVGKSSLINKLLGEERLIVSDIPGTTRDSIDSYVDTEFGEFTLIDTAGLRRKSKVK
EEIERYSVIRTYASIERADVCILMIDATEGISEQDQKIIGYAHDINKAILVIVNKWDLVEKDDKTMDKFKKELKVNLSFM
PYAKYLFISAKTGQRVVKVLQTAKECYDNYTKRVKTGVLNDVISQAIMMKEPPIVGTKRLKIYYVTQIGTKPPTFIFFVN
DPACIHFSYQRYLENQLRENFDFQGTGIKLEFRERKEK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Homo sapiens, GI193082991, Length=133, Percent_Identity=33.0827067669173, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI193082988, Length=133, Percent_Identity=33.0827067669173, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082120, Length=460, Percent_Identity=40, Blast_Score=347, Evalue=6e-97,
Organism=Escherichia coli, GI1788919, Length=123, Percent_Identity=39.8373983739837, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI2367268, Length=95, Percent_Identity=43.1578947368421, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17507259, Length=193, Percent_Identity=30.5699481865285, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=224, Percent_Identity=31.6964285714286, Blast_Score=97, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49794; Mature: 49663

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVQDTPGVTRDRIYAEAEWLNYKFTMIDTGG
CCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHEEEEEEEEEEEEEEEECCC
IEPKSEDIIVSQMRRQAQIAIEMANVIIFLVDGKEGLAPADEEVAQMLRKSKKPVVLVVN
CCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEE
KIDKLKDENNAYEFYNLGIGDPVTISSSQALGLGDMLDRVVEYFKDDESDGEDDERINIA
CHHHCCCCCCCEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEE
FIGKPNVGKSSLINKLLGEERLIVSDIPGTTRDSIDSYVDTEFGEFTLIDTAGLRRKSKV
EEECCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHH
KEEIERYSVIRTYASIERADVCILMIDATEGISEQDQKIIGYAHDINKAILVIVNKWDLV
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHEEEHCCCCCEEEEEEECCCCC
EKDDKTMDKFKKELKVNLSFMPYAKYLFISAKTGQRVVKVLQTAKECYDNYTKRVKTGVL
CCCCHHHHHHHHHHEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDVISQAIMMKEPPIVGTKRLKIYYVTQIGTKPPTFIFFVNDPACIHFSYQRYLENQLRE
HHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCEEEEEHHHHHHHHHHHH
NFDFQGTGIKLEFRERKEK
CCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
GKPIVAIVGRPNVGKSTLFNKLAGKRIAIVQDTPGVTRDRIYAEAEWLNYKFTMIDTGG
CCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHEEEEEEEEEEEEEEEECCC
IEPKSEDIIVSQMRRQAQIAIEMANVIIFLVDGKEGLAPADEEVAQMLRKSKKPVVLVVN
CCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEE
KIDKLKDENNAYEFYNLGIGDPVTISSSQALGLGDMLDRVVEYFKDDESDGEDDERINIA
CHHHCCCCCCCEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEE
FIGKPNVGKSSLINKLLGEERLIVSDIPGTTRDSIDSYVDTEFGEFTLIDTAGLRRKSKV
EEECCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHH
KEEIERYSVIRTYASIERADVCILMIDATEGISEQDQKIIGYAHDINKAILVIVNKWDLV
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHEEEHCCCCCEEEEEEECCCCC
EKDDKTMDKFKKELKVNLSFMPYAKYLFISAKTGQRVVKVLQTAKECYDNYTKRVKTGVL
CCCCHHHHHHHHHHEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDVISQAIMMKEPPIVGTKRLKIYYVTQIGTKPPTFIFFVNDPACIHFSYQRYLENQLRE
HHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCEEEEEHHHHHHHHHHHH
NFDFQGTGIKLEFRERKEK
CCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA