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The map label for this gene is gpsA [H]

Identifier: 226949874

GI number: 226949874

Start: 2831635

End: 2832633

Strand: Reverse

Name: gpsA [H]

Synonym: CLM_2823

Alternate gene names: 226949874

Gene position: 2832633-2831635 (Counterclockwise)

Preceding gene: 226949875

Following gene: 226949872

Centisome position: 68.17

GC content: 31.83

Gene sequence:

>999_bases
ATGGATTCAACAGTTTGTTTTTTAGCAGCAGGTAGTTTTGGAACAGCTTTAGCTGTAATGTTAGGAAAAAAAGGATTGAA
AGTTAACATATGGCATAGAAATAATAACATAGTAGAGGATATAAATATCAAAAAAGAAAATATAAAATATTTACCTAAAG
TAGTAATACCTGCAGGGATAAAAGCTTATAATGAAATAGAAAAAAGTATAGAGCAATGTGAATTTATAGTATTAGCAGTA
CCTTCTCATGTGGTAAGACAGGTATGCAAAAAAATACAACCTTTTATAAAAGAAAATCAAATAATAGTAAGTATAGCTAA
AGGTATAGAAGAGGGTACAGGGAAAAGGTTATCAGAGGTTATAAAAGAAGAACTGCCTAATAATCCCATAGTAATATTGT
CAGGCCCTAGTCATGCAGAGGAAGTAGCTCAAGATATACCTACCACAGTAGTTGTGTCTTCAGAACATATGGATATAGCT
GAAAAAGTTCAGGATCTTTTTATGACTAATAAATTTAGAGTGTATACTAATGATGATTTAATAGGAGTAGAAATAGGAGG
CGCTGTTAAAAATATTATAGCTTTAGCTGCAGGGGTATCTGATGGTATAGGTTATGGAGATAACACAAAAGCAGCTTTAA
TGACAAGAGGTATGAGTGAGATAATAAGAATAGGTACAAAGCTTGGAGGAAAACAGGAAACCTTTTCAGGTCTTACAGGC
ATGGGAGATTTAATAGTTACTTGCACAAGTATGCATAGTAGAAATAGAAGAGCGGGTATATTAATTGGTAAAGGTTATAG
CACGGAAGAAGCAATAGAAGAAGTAGGTATGGTAGTAGAAGGGATAAAAGCTTGTAGAGCCTTTTATACATTAAAAGAAA
AGCTAGATGTAGAAATGCCTATAACAGATACATTATATAAAGTTTTATTTGAAAATAAAGAGCCTAATTATGGGGTCTAT
GAACTTATGACTAGGGATAAAAAAATGGAAATAATTTAA

Upstream 100 bases:

>100_bases
ATAGGAATTTTTAATATAAACTTATTTCTTAAATTAATTTTAAAGATCAATTGAAAATTTTAATTAGCTTAATAATTAAT
TGGGGAAAGGAAGGAATAAA

Downstream 100 bases:

>100_bases
GATATTAATTATATATAAAGTACTAATCTAAAGGTAGAAGATGTCTTTTACCTTTTAGATTAGTGCTTTTTACATTATCT
TAAGAATAGCAACTGACGCT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MDSTVCFLAAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGIKAYNEIEKSIEQCEFIVLAV
PSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEVIKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIA
EKVQDLFMTNKFRVYTNDDLIGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMPITDTLYKVLFENKEPNYGVY
ELMTRDKKMEII

Sequences:

>Translated_332_residues
MDSTVCFLAAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGIKAYNEIEKSIEQCEFIVLAV
PSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEVIKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIA
EKVQDLFMTNKFRVYTNDDLIGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMPITDTLYKVLFENKEPNYGVY
ELMTRDKKMEII
>Mature_332_residues
MDSTVCFLAAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGIKAYNEIEKSIEQCEFIVLAV
PSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEVIKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIA
EKVQDLFMTNKFRVYTNDDLIGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMPITDTLYKVLFENKEPNYGVY
ELMTRDKKMEII

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=347, Percent_Identity=28.8184438040346, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24307999, Length=332, Percent_Identity=30.1204819277108, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=38.0664652567976, Blast_Score=263, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI32564399, Length=335, Percent_Identity=30.4477611940298, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193210136, Length=344, Percent_Identity=29.9418604651163, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI32564403, Length=344, Percent_Identity=29.9418604651163, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17507425, Length=333, Percent_Identity=26.1261261261261, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193210134, Length=332, Percent_Identity=28.0120481927711, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324513, Length=340, Percent_Identity=28.2352941176471, Blast_Score=122, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320181, Length=340, Percent_Identity=28.2352941176471, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136204, Length=335, Percent_Identity=29.8507462686567, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136200, Length=335, Percent_Identity=29.8507462686567, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136202, Length=335, Percent_Identity=29.8507462686567, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI22026922, Length=326, Percent_Identity=28.8343558282209, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI45551945, Length=294, Percent_Identity=26.1904761904762, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281362270, Length=294, Percent_Identity=26.1904761904762, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24648969, Length=255, Percent_Identity=27.4509803921569, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36498; Mature: 36498

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTVCFLAAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGI
CCCEEEEEECCCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCHHHHHHCCHHHCCCCH
KAYNEIEKSIEQCEFIVLAVPSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEV
HHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCHHHHHH
IKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIAEKVQDLFMTNKFRVYTNDDL
HHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCE
IGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
EEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMP
CCHHHHEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ITDTLYKVLFENKEPNYGVYELMTRDKKMEII
HHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MDSTVCFLAAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGI
CCCEEEEEECCCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCHHHHHHCCHHHCCCCH
KAYNEIEKSIEQCEFIVLAVPSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEV
HHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCHHHHHH
IKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIAEKVQDLFMTNKFRVYTNDDL
HHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCE
IGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
EEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMP
CCHHHHEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ITDTLYKVLFENKEPNYGVYELMTRDKKMEII
HHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]