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The map label for this gene is ycbL [H]

Identifier: 226949656

GI number: 226949656

Start: 2626336

End: 2627043

Strand: Reverse

Name: ycbL [H]

Synonym: CLM_2593

Alternate gene names: 226949656

Gene position: 2627043-2626336 (Counterclockwise)

Preceding gene: 226949658

Following gene: 226949655

Centisome position: 63.22

GC content: 31.78

Gene sequence:

>708_bases
ATGGAAAAATTAAAGATATTAATTGTAGAAGATGATGTTAATATAAATAATATGATAAAGGAATCATTGATAAAGGAAGG
ATATGATATCGGGCAAGCTTTTCATGGACTTGAAGCTGTGGAAAAATTTCAAGGTGAAGATTATCATATGGTAATTATGG
ATGTTATGATGCCTGTTATGGATGGCATCGAGGCAATGAGAAGAATCAGGGAAAAAAGTAAAGTTCCAATTATAATACTT
TCTGCAAAGGGAGAAGACAGTGACAAAATAATAGGACTTGGTATGGGAGCGGATGATTACATTGTGAAACCATTTTCAGT
GCCAGAGCTTATAGCAAGAGTTAAATGTAATATAAGAAGAGCTATTTATTATAATGAAACCAAAAGTATTAAAGAAAATA
AGATACATGAGTATGGTGATGTGAAATTTGATATGAATAATTACACAGTTACCAAAGGAGGAAAGGAACTTACTCTTACT
GCAAAGGAAATGAAAATTCTTAAGCTTTTCTTTGAAAATCCAAACAGAGTATTTACTAAAGTGCAGATATATGACAGTGT
ATGGGGAGAAGAATTTTTATCAGATTATAATACGGTAACAGTGCATATGAGAAGGCTTAGAAGTAAAATCGAGGATGATC
CTAATAACCCTAAACTTATAGAAACTGTTTGGGGAATAGGATACAAATTAACAGGTGATAGACAATGA

Upstream 100 bases:

>100_bases
TATTTGTATATAGGTAGCTTATATAAATAATCATAAAAATATTATGAAAGGGAAAAGTATAATAAATTTTTATTATAGAT
TTAGTATATAAGGTGATATT

Downstream 100 bases:

>100_bases
GTTGGATATTAATAATTATTATAATAATACTATCTATACTATTATTAAATGATAAAATAAAAACTAAAAGAATTACGGCA
AAATTAAAAGAGATTCTTAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MEKLKILIVEDDVNINNMIKESLIKEGYDIGQAFHGLEAVEKFQGEDYHMVIMDVMMPVMDGIEAMRRIREKSKVPIIIL
SAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRRAIYYNETKSIKENKIHEYGDVKFDMNNYTVTKGGKELTLT
AKEMKILKLFFENPNRVFTKVQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDRQ

Sequences:

>Translated_235_residues
MEKLKILIVEDDVNINNMIKESLIKEGYDIGQAFHGLEAVEKFQGEDYHMVIMDVMMPVMDGIEAMRRIREKSKVPIIIL
SAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRRAIYYNETKSIKENKIHEYGDVKFDMNNYTVTKGGKELTLT
AKEMKILKLFFENPNRVFTKVQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDRQ
>Mature_235_residues
MEKLKILIVEDDVNINNMIKESLIKEGYDIGQAFHGLEAVEKFQGEDYHMVIMDVMMPVMDGIEAMRRIREKSKVPIIIL
SAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRRAIYYNETKSIKENKIHEYGDVKFDMNNYTVTKGGKELTLT
AKEMKILKLFFENPNRVFTKVQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDRQ

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=31.3304721030043, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=34.4978165938865, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=36.4035087719298, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=32.8888888888889, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=31.9327731092437, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=31.7391304347826, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=35.6521739130435, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=30.1310043668122, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=32.1888412017167, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1790860, Length=235, Percent_Identity=30.2127659574468, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=29.004329004329, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=28.3842794759825, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=27.7533039647577, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=28.0701754385965, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=34.5794392523364, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788713, Length=107, Percent_Identity=36.4485981308411, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=113, Percent_Identity=31.858407079646, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790299, Length=133, Percent_Identity=27.0676691729323, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790437, Length=105, Percent_Identity=29.5238095238095, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27151; Mature: 27151

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLKILIVEDDVNINNMIKESLIKEGYDIGQAFHGLEAVEKFQGEDYHMVIMDVMMPVM
CCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
DGIEAMRRIREKSKVPIIILSAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRR
HHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHEE
AIYYNETKSIKENKIHEYGDVKFDMNNYTVTKGGKELTLTAKEMKILKLFFENPNRVFTK
EEEECCCCCHHHHCCHHCCCEEEECCCEEEECCCCEEEEEHHHHHHHHHHHCCCCEEEEE
VQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDRQ
EEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEECCCCC
>Mature Secondary Structure
MEKLKILIVEDDVNINNMIKESLIKEGYDIGQAFHGLEAVEKFQGEDYHMVIMDVMMPVM
CCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
DGIEAMRRIREKSKVPIIILSAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRR
HHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHEE
AIYYNETKSIKENKIHEYGDVKFDMNNYTVTKGGKELTLTAKEMKILKLFFENPNRVFTK
EEEECCCCCHHHHCCHHCCCEEEECCCEEEECCCCEEEEEHHHHHHHHHHHCCCCEEEEE
VQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDRQ
EEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]