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The map label for this gene is fruR [H]

Identifier: 226949478

GI number: 226949478

Start: 2493489

End: 2494247

Strand: Reverse

Name: fruR [H]

Synonym: CLM_2411

Alternate gene names: 226949478

Gene position: 2494247-2493489 (Counterclockwise)

Preceding gene: 226949480

Following gene: 226949477

Centisome position: 60.03

GC content: 28.19

Gene sequence:

>759_bases
ATGCTTCCAGTAGAGAGAGAGCAATACATAATTGAAAAGCTAGAAGATCTAGGAACTGTGAAAGTTGAAGATATTGCTAA
TGAACTAGATGTAAGTTTAATGACTATAAGAAGAGATTTTGATAGATTACAGGATAAGGGTATTTTATATAGGAGTCATG
GGGGAGCAGTAAAACGTTCTACTTATTTATCAGAACAAGCCTATGACTTAAAGAAGATAAGCAATATATACGTAAAAGAA
AAAATAGCAGAAAAAGCTTTAAGTATAATTAAAGAAGGAGACAGTATATTTTTAGATGCAGGTACTACAACTTTTGAATT
GGCTAAAGTGCTTAACAAAGTAAAAGATATAACAGTTATAACAAACGATCTTAAAATAGCTTTAGAATTGTATCAAAACA
ATGTGAAAGCTTATATAGTAGGTGGGAAAATACAAGAAGAAACAGGATGTATAATAGGTCCTACTGCAGATGAATTTATA
TCTAATATAAAAGTTAATGTAGCTTTCTTAGGAACCTCTGGCATAGATTCTGATTTTAGACTATCTACTCCTACCTTTGA
AAAGGCAAACTTAAAGAAGCGTATAGTAAAATCAGCATCTTATTCTGTTCTTTTAACAGATAGTAGTAAGTTTAATAAGA
AATCCTTTGTAAATATATTTTCTATAGAATCAGTAAATTGTGTCATTACAGATAAAAAAATTGATAAAGATGAAGATAAA
TATTTAGAATCATTAAATGTAAAAATAATCAATGTATAA

Upstream 100 bases:

>100_bases
GAACAAATAAAACGAAAAGAAAAACACAAATTAAGTTTCATAAGTAAATTAGATTAATATAGATTAATTTGTTTTTATAC
TGAAAATAAGAGGTGATAGG

Downstream 100 bases:

>100_bases
ATAGGAATTTTATTCAATGAATCCTATGAAGTTTAGCAAATGATTGGTTCGAGGGGGACATTAAATGTTAAATTATGTTA
TTATAGCTGACGATTTGACG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLPVEREQYIIEKLEDLGTVKVEDIANELDVSLMTIRRDFDRLQDKGILYRSHGGAVKRSTYLSEQAYDLKKISNIYVKE
KIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVITNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFI
SNIKVNVAFLGTSGIDSDFRLSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKKSFVNIFSIESVNCVITDKKIDKDEDK
YLESLNVKIINV

Sequences:

>Translated_252_residues
MLPVEREQYIIEKLEDLGTVKVEDIANELDVSLMTIRRDFDRLQDKGILYRSHGGAVKRSTYLSEQAYDLKKISNIYVKE
KIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVITNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFI
SNIKVNVAFLGTSGIDSDFRLSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKKSFVNIFSIESVNCVITDKKIDKDEDK
YLESLNVKIINV
>Mature_252_residues
MLPVEREQYIIEKLEDLGTVKVEDIANELDVSLMTIRRDFDRLQDKGILYRSHGGAVKRSTYLSEQAYDLKKISNIYVKE
KIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVITNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFI
SNIKVNVAFLGTSGIDSDFRLSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKKSFVNIFSIESVNCVITDKKIDKDEDK
YLESLNVKIINV

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=31.7269076305221, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789829, Length=232, Percent_Identity=32.7586206896552, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789059, Length=252, Percent_Identity=34.5238095238095, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI226510968, Length=243, Percent_Identity=29.6296296296296, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082344, Length=228, Percent_Identity=29.3859649122807, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=29.0836653386454, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787540, Length=250, Percent_Identity=29.2, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789170, Length=235, Percent_Identity=30.6382978723404, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790753, Length=200, Percent_Identity=33, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1790635, Length=262, Percent_Identity=25.1908396946565, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787063, Length=253, Percent_Identity=22.9249011857708, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28321; Mature: 28321

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVEREQYIIEKLEDLGTVKVEDIANELDVSLMTIRRDFDRLQDKGILYRSHGGAVKRS
CCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEHH
TYLSEQAYDLKKISNIYVKEKIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCEEEE
TNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFISNIKVNVAFLGTSGIDSDFR
ECCHHEEEEEHHCCEEEEEECCEEECCCCEEECCCHHHHHHCCEEEEEEEECCCCCCCCE
LSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKKSFVNIFSIESVNCVITDKKIDKDEDK
ECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCEEEEEECCCCCCCHHH
YLESLNVKIINV
HHHHCCEEEEEC
>Mature Secondary Structure
MLPVEREQYIIEKLEDLGTVKVEDIANELDVSLMTIRRDFDRLQDKGILYRSHGGAVKRS
CCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEHH
TYLSEQAYDLKKISNIYVKEKIAEKALSIIKEGDSIFLDAGTTTFELAKVLNKVKDITVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCEEEE
TNDLKIALELYQNNVKAYIVGGKIQEETGCIIGPTADEFISNIKVNVAFLGTSGIDSDFR
ECCHHEEEEEHHCCEEEEEECCEEECCCCEEECCCHHHHHHCCEEEEEEEECCCCCCCCE
LSTPTFEKANLKKRIVKSASYSVLLTDSSKFNKKSFVNIFSIESVNCVITDKKIDKDEDK
ECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCEEEEEECCCCCCCHHH
YLESLNVKIINV
HHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]