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The map label for this gene is bcd [H]

Identifier: 226949464

GI number: 226949464

Start: 2474690

End: 2475823

Strand: Reverse

Name: bcd [H]

Synonym: CLM_2397

Alternate gene names: 226949464

Gene position: 2475823-2474690 (Counterclockwise)

Preceding gene: 226949465

Following gene: 226949463

Centisome position: 59.58

GC content: 34.83

Gene sequence:

>1134_bases
ATGTTATTTAAAAAAGAGCATGAACTTTTAAGAAAGTCCGTAATGGATTTTGTAGATAGGGAATTAAAAGATATTCCAGA
AGAAGTTGATACTGAGGGGAAACTACCTAAAGAGTTATTACAAAAGCTTGCAAAATATAAATTCATAAGTCCTGTAATAC
CTAAGGAATATGGTGGAGCTGGAGCAGACTATGTATCATACTGCATAATAATGGAGGAAATCAGTAAAAGATGCGCATCT
ACTGGAACTTTTATAACAGCAGGAGCATCATTAGTAGCATTACCTTTACTTAATTTTGGAACAGAGGAGCAAAAAGAAAA
ATATTTAAAACCTCTTGCTAAAGGTGAATATATTGGATCCTTTGGACTTACAGAACCAGGAGCAGGATCTGACGCTGGTG
CTGGTCAAACTACAGCAGTTTTAGAGGGAGATCATTATATTTTAAATGGAAGAAAAACATTCATTACAAATGCACCTATT
TGTGACTTTGCTATAGTAACAGCAATGACAGAAAAGGGTAAAGGATCAAGGGGGATTTCAGCCTTTATAGTTGAAAGTAA
ATGGGATGGATTTTCAACAGGAGCTCATGAAAATAAAATGGGCATTAGAGGAACTGAGACAGCGGATTTAATATTTGAAA
ATGTAAAAGTTCCTAAAGAAAACCTTATTGGAAAAGAAGGCAAAGGATTTAAAATAGCTCTAAATACTCTTGATGTTGGT
AGAATCGGGGTAGCAGCTCAAGCTCTTGGAATAGCTCAAGGTGCTTTAGATGAAGCTATAAAGTATGTTAAGGAAAGAGT
TCAGTTTGGTAAGCCTTTAGCAAAATTCCAAAATACTCAATTTACAATTGCAGATATGGAAACAAAGGTTCAAGCTGCAA
GATGGCTTGTATATGATGCAGCAGAGAAGAAAGACAATGGTATAAATCCAGGTGTTGAATCTGCAATGGCTAAATATTAT
GCAGCGGAAATTGCAAATGAAGTAGCATATAAAGCATTACAATTACATGGCGGATATGGATTTATGAAGGATTATCCAAT
AGAAAGAATGTATAGAGATGCTAGAATTACATCTATATATGAAGGTACATCTCAAGTTCAGCAAATGGTTATTGCTGCGA
AAGCTCTTAAATAG

Upstream 100 bases:

>100_bases
ATGAAACTAAAAAAAGTATAGGGATTTATAAATACTTTAAAAAATTAAAATGAAAGATCACTACATTTTATTAAAGGTTT
AAATTTAAAAGGAGGAAAGT

Downstream 100 bases:

>100_bases
ATATATGAGAAATAAACAAAATTGGAGGTTAAGAATTTGAGGATAGTAGTATGTGTTAAGCAAGTTCCAGATACAACAGA
AGTAAAGATAGATCCTAAAA

Product: acyl-CoA dehydrogenase family protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MLFKKEHELLRKSVMDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCAS
TGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGQTTAVLEGDHYILNGRKTFITNAPI
CDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYY
AAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAAKALK

Sequences:

>Translated_377_residues
MLFKKEHELLRKSVMDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCAS
TGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGQTTAVLEGDHYILNGRKTFITNAPI
CDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYY
AAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAAKALK
>Mature_377_residues
MLFKKEHELLRKSVMDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCAS
TGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGQTTAVLEGDHYILNGRKTFITNAPI
CDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYY
AAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAAKALK

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=47.2, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI4501859, Length=370, Percent_Identity=41.6216216216216, Blast_Score=292, Evalue=4e-79,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=38.8739946380697, Blast_Score=266, Evalue=3e-71,
Organism=Homo sapiens, GI226958414, Length=370, Percent_Identity=38.6486486486486, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=37.696335078534, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI187960098, Length=373, Percent_Identity=37.5335120643432, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI4557231, Length=373, Percent_Identity=37.5335120643432, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=35.8288770053476, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI21361497, Length=358, Percent_Identity=39.1061452513966, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI4557235, Length=381, Percent_Identity=33.3333333333333, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI76496475, Length=381, Percent_Identity=33.3333333333333, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI4503943, Length=338, Percent_Identity=31.6568047337278, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI7669494, Length=328, Percent_Identity=32.0121951219512, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI48976061, Length=293, Percent_Identity=31.740614334471, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI211971008, Length=293, Percent_Identity=31.740614334471, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI38505218, Length=397, Percent_Identity=29.4710327455919, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI218563752, Length=202, Percent_Identity=31.6831683168317, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=30.7086614173228, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786223, Length=355, Percent_Identity=30.4225352112676, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI87081702, Length=356, Percent_Identity=27.5280898876405, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082384, Length=308, Percent_Identity=23.7012987012987, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=39.4594594594595, Blast_Score=283, Evalue=7e-77,
Organism=Caenorhabditis elegans, GI17534899, Length=345, Percent_Identity=42.3188405797101, Blast_Score=268, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=38.5869565217391, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17569725, Length=346, Percent_Identity=39.8843930635838, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17570075, Length=370, Percent_Identity=37.8378378378378, Blast_Score=251, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=37.9310344827586, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17538396, Length=364, Percent_Identity=34.8901098901099, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71990804, Length=270, Percent_Identity=44.0740740740741, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI71985184, Length=368, Percent_Identity=36.6847826086957, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=39.2727272727273, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71985192, Length=303, Percent_Identity=35.6435643564356, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI32563615, Length=225, Percent_Identity=39.5555555555556, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17534353, Length=317, Percent_Identity=34.0694006309148, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=29.9465240641711, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=29.144385026738, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=37.5527426160338, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17562446, Length=342, Percent_Identity=32.7485380116959, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=34.0909090909091, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI86563381, Length=266, Percent_Identity=30.0751879699248, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI86563383, Length=266, Percent_Identity=30.0751879699248, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540912, Length=378, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=48.2666666666667, Blast_Score=355, Evalue=3e-98,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=42.4, Blast_Score=307, Evalue=6e-84,
Organism=Drosophila melanogaster, GI24666513, Length=367, Percent_Identity=38.9645776566758, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24660351, Length=369, Percent_Identity=38.4823848238482, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=36.3636363636364, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI281363737, Length=386, Percent_Identity=34.4559585492228, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=28.686327077748, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24652780, Length=264, Percent_Identity=26.1363636363636, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41262; Mature: 41262

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKKEHELLRKSVMDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCC
GADYVSYCIIMEEISKRCASTGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGS
CHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
FGLTEPGAGSDAGAGQTTAVLEGDHYILNGRKTFITNAPICDFAIVTAMTEKGKGSRGIS
CCCCCCCCCCCCCCCCEEEEEECCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCE
AFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCEEEEEEEECCC
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHHHHHHHHHEEC
AEKKDNGINPGVESAMAKYYAAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIY
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EGTSQVQQMVIAAKALK
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFKKEHELLRKSVMDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCC
GADYVSYCIIMEEISKRCASTGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGS
CHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
FGLTEPGAGSDAGAGQTTAVLEGDHYILNGRKTFITNAPICDFAIVTAMTEKGKGSRGIS
CCCCCCCCCCCCCCCCEEEEEECCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCE
AFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCEEEEEEEECCC
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHHHHHHHHHEEC
AEKKDNGINPGVESAMAKYYAAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIY
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EGTSQVQQMVIAAKALK
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]