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The map label for this gene is moaC [H]

Identifier: 226949237

GI number: 226949237

Start: 2212201

End: 2212680

Strand: Reverse

Name: moaC [H]

Synonym: CLM_2156

Alternate gene names: 226949237

Gene position: 2212680-2212201 (Counterclockwise)

Preceding gene: 226949238

Following gene: 226949236

Centisome position: 53.25

GC content: 31.67

Gene sequence:

>480_bases
ATGGAATTAACACATATAAATAAGCAAGGAAGAGCAAAAATGGTGGATGTAGGCAATAAAGGAGATACAGAAAGGGAAGC
TATTGCCTATGGATATGTAAACATGAAGAGAGAAACTTTAAATAAAATAAAAGAAGGTACCATATCAAAGGGAGACGTGC
TATCTGTAGCTCAAGTAGCAGGTATTATGGCAGCAAAAAATACAGCTAATATTATACCTATGTGTCATCCTATAATGATA
AACGGTTGTGACATAAATTTTAACTTGGATTTTGAAAACAATAATATAGATATAACATCTTCAGTAAAAAATACAGGAAA
AACGGGAGTAGAAATGGAAGCTTTAACTGCAGTTACAGTAGCAGCTTTAACTATCTATGATATGTGTAAAGCTATAGATA
GAGAAATGACAATATCAGATGTAAAACTTATGAAAAAAAGTGGGGGAAAATCAGGATTATTTCAAAGGGAGGAATTATAA

Upstream 100 bases:

>100_bases
GATAAATGAAACTATTTATAACAAACCCTTAGAGCATCATATGATAGAGGAAAAAGAAAGTAAAAGCAAAAAAATGATGT
ATCAGATTGGAGGTTAGCTT

Downstream 100 bases:

>100_bases
CATGGCAAAGGTAATAGCAGTTAATATAAGTGAAAAAAAAGGTGAGATAAAACATCCTATAGATAAGGGGTTATTTAAAG
TAGATCACGGTCTTGTAGGA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MELTHINKQGRAKMVDVGNKGDTEREAIAYGYVNMKRETLNKIKEGTISKGDVLSVAQVAGIMAAKNTANIIPMCHPIMI
NGCDINFNLDFENNNIDITSSVKNTGKTGVEMEALTAVTVAALTIYDMCKAIDREMTISDVKLMKKSGGKSGLFQREEL

Sequences:

>Translated_159_residues
MELTHINKQGRAKMVDVGNKGDTEREAIAYGYVNMKRETLNKIKEGTISKGDVLSVAQVAGIMAAKNTANIIPMCHPIMI
NGCDINFNLDFENNNIDITSSVKNTGKTGVEMEALTAVTVAALTIYDMCKAIDREMTISDVKLMKKSGGKSGLFQREEL
>Mature_159_residues
MELTHINKQGRAKMVDVGNKGDTEREAIAYGYVNMKRETLNKIKEGTISKGDVLSVAQVAGIMAAKNTANIIPMCHPIMI
NGCDINFNLDFENNNIDITSSVKNTGKTGVEMEALTAVTVAALTIYDMCKAIDREMTISDVKLMKKSGGKSGLFQREEL

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=53.8461538461538, Blast_Score=176, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=49.6644295302013, Blast_Score=156, Evalue=5e-39,
Organism=Drosophila melanogaster, GI28574490, Length=157, Percent_Identity=49.0445859872611, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=48.9655172413793, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17361; Mature: 17361

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTHINKQGRAKMVDVGNKGDTEREAIAYGYVNMKRETLNKIKEGTISKGDVLSVAQVA
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEHHHCCCHHHHHHHHHCCCCCCCHHHHHHHH
GIMAAKNTANIIPMCHPIMINGCDINFNLDFENNNIDITSSVKNTGKTGVEMEALTAVTV
HHHHCCCCCCCCCCCCEEEEECCEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHH
AALTIYDMCKAIDREMTISDVKLMKKSGGKSGLFQREEL
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MELTHINKQGRAKMVDVGNKGDTEREAIAYGYVNMKRETLNKIKEGTISKGDVLSVAQVA
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEHHHCCCHHHHHHHHHCCCCCCCHHHHHHHH
GIMAAKNTANIIPMCHPIMINGCDINFNLDFENNNIDITSSVKNTGKTGVEMEALTAVTV
HHHHCCCCCCCCCCCCEEEEECCEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHH
AALTIYDMCKAIDREMTISDVKLMKKSGGKSGLFQREEL
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA