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The map label for this gene is cheV [H]

Identifier: 226949021

GI number: 226949021

Start: 1986112

End: 1987005

Strand: Reverse

Name: cheV [H]

Synonym: CLM_1935

Alternate gene names: 226949021

Gene position: 1987005-1986112 (Counterclockwise)

Preceding gene: 226949028

Following gene: 226949019

Centisome position: 47.82

GC content: 28.86

Gene sequence:

>894_bases
ATGGAGACTAATATATTATTAGAGTCTGGTACAGGCGAAGTAGAAATAATAGAATTTTTAGTTAATAATAAACACTATGC
TATTAATGTTATAAAAGTAAAAGAAGTAATAGAAGTAGATAATGTAACTAAGGTACCTCAAAGTGATCCAGCTATAGAAG
GATTAATTCTATGTAGGGAAAAGATTTTCCCACTAATAGACCTTTCTTATATATTGGGTCAAAAGAATACTTCGAAGGGG
AAATTTAAAACTATCATATGTGAATTCAATAGAGTTAGTGTAGCTTTTAAAATAGATGAAATAGTAGCTGTTCATAGAAT
AGGTTGGGACAAAATATTGAAACCAGATGACATAGCTGCTAACCCATTGGTCATAGGGAACATATTATTAAAAGATAAAA
TTATATTATTATTAGATTTTGAAAAAATAGTTACAGATATAAATCCAAGTACAGGTATTAGTGAAGAAAGAATAGTTAAT
GTGGATTACAAAGATAGATCTCATATTAAGGTATTCTTAGCTGATGATTCTTCCTTAATAAGAAAGCTTTTAAAAGACAC
CCTTACTAAAGCTGGATTTAAAAAGCTAACCATATTTGACGATGGAAAGCAAGTTTTAGACAAGCTACTTGAACTAGTAG
AAAAAAAAGGTGAAGATTTCACAGAGGATGTACAAATTCTTATTACAGATATAGAAATGCCCCAAATGGATGGCCATACT
CTTACAAGAAAAGTTAAAGAACACCCAATACTTAAAAGACTTCCTGTTATAATATTTTCCTCTTTAATTACAAAGGATTT
AAAACATAAAGGAACCTCTGTAGGAGCGGATGAACAATTAAGTAAACCAGATATAGGAGAATTAGTAAATATAATAGATA
ATTATATAGAATAA

Upstream 100 bases:

>100_bases
AGCAAGTAAAAATATAAAGTAATATTTTTTATATACGAAATATACAATAAATAAAATATAAGCATTTTTTTTGCTATAAT
CCAGAAAGTGGGGTAATAAA

Downstream 100 bases:

>100_bases
TTCTAACTAATTAAGCGATTCACTACAAATAACAGATTTGCAGCGAGTCGCTTAATCCTATGACAAATGAATAGGAGTTT
CATAAGCAGGGAACACAAAT

Product: chemotaxis protein CheV

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
METNILLESGTGEVEIIEFLVNNKHYAINVIKVKEVIEVDNVTKVPQSDPAIEGLILCREKIFPLIDLSYILGQKNTSKG
KFKTIICEFNRVSVAFKIDEIVAVHRIGWDKILKPDDIAANPLVIGNILLKDKIILLLDFEKIVTDINPSTGISEERIVN
VDYKDRSHIKVFLADDSSLIRKLLKDTLTKAGFKKLTIFDDGKQVLDKLLELVEKKGEDFTEDVQILITDIEMPQMDGHT
LTRKVKEHPILKRLPVIIFSSLITKDLKHKGTSVGADEQLSKPDIGELVNIIDNYIE

Sequences:

>Translated_297_residues
METNILLESGTGEVEIIEFLVNNKHYAINVIKVKEVIEVDNVTKVPQSDPAIEGLILCREKIFPLIDLSYILGQKNTSKG
KFKTIICEFNRVSVAFKIDEIVAVHRIGWDKILKPDDIAANPLVIGNILLKDKIILLLDFEKIVTDINPSTGISEERIVN
VDYKDRSHIKVFLADDSSLIRKLLKDTLTKAGFKKLTIFDDGKQVLDKLLELVEKKGEDFTEDVQILITDIEMPQMDGHT
LTRKVKEHPILKRLPVIIFSSLITKDLKHKGTSVGADEQLSKPDIGELVNIIDNYIE
>Mature_297_residues
METNILLESGTGEVEIIEFLVNNKHYAINVIKVKEVIEVDNVTKVPQSDPAIEGLILCREKIFPLIDLSYILGQKNTSKG
KFKTIICEFNRVSVAFKIDEIVAVHRIGWDKILKPDDIAANPLVIGNILLKDKIILLLDFEKIVTDINPSTGISEERIVN
VDYKDRSHIKVFLADDSSLIRKLLKDTLTKAGFKKLTIFDDGKQVLDKLLELVEKKGEDFTEDVQILITDIEMPQMDGHT
LTRKVKEHPILKRLPVIIFSSLITKDLKHKGTSVGADEQLSKPDIGELVNIIDNYIE

Specific function: Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW function together to couple CheA activation to methyl-accepting chemotaxis protein receptor status and possible CheA-dependent phosphoryl

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 33536; Mature: 33536

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50851 CHEW ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNILLESGTGEVEIIEFLVNNKHYAINVIKVKEVIEVDNVTKVPQSDPAIEGLILCRE
CCCCEEEECCCCCEEEEEEECCCCEEEEEEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KIFPLIDLSYILGQKNTSKGKFKTIICEFNRVSVAFKIDEIVAVHRIGWDKILKPDDIAA
HCCCHHHHHHHHCCCCCCCCCEEEEEEEECEEEEEEEHHHHHHHHHCCHHHCCCCCCCCC
NPLVIGNILLKDKIILLLDFEKIVTDINPSTGISEERIVNVDYKDRSHIKVFLADDSSLI
CCEEEEEEEECCCEEEEEEHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEEEECCHHHH
RKLLKDTLTKAGFKKLTIFDDGKQVLDKLLELVEKKGEDFTEDVQILITDIEMPQMDGHT
HHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHH
LTRKVKEHPILKRLPVIIFSSLITKDLKHKGTSVGADEQLSKPDIGELVNIIDNYIE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
METNILLESGTGEVEIIEFLVNNKHYAINVIKVKEVIEVDNVTKVPQSDPAIEGLILCRE
CCCCEEEECCCCCEEEEEEECCCCEEEEEEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KIFPLIDLSYILGQKNTSKGKFKTIICEFNRVSVAFKIDEIVAVHRIGWDKILKPDDIAA
HCCCHHHHHHHHCCCCCCCCCEEEEEEEECEEEEEEEHHHHHHHHHCCHHHCCCCCCCCC
NPLVIGNILLKDKIILLLDFEKIVTDINPSTGISEERIVNVDYKDRSHIKVFLADDSSLI
CCEEEEEEEECCCEEEEEEHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEEEECCHHHH
RKLLKDTLTKAGFKKLTIFDDGKQVLDKLLELVEKKGEDFTEDVQILITDIEMPQMDGHT
HHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHH
LTRKVKEHPILKRLPVIIFSSLITKDLKHKGTSVGADEQLSKPDIGELVNIIDNYIE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8169223; 9384377; 8169224 [H]