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The map label for this gene is ykpA [H]

Identifier: 226949019

GI number: 226949019

Start: 1983002

End: 1984582

Strand: Reverse

Name: ykpA [H]

Synonym: CLM_1933

Alternate gene names: 226949019

Gene position: 1984582-1983002 (Counterclockwise)

Preceding gene: 226949021

Following gene: 226949017

Centisome position: 47.76

GC content: 31.25

Gene sequence:

>1581_bases
TTGATTACAGTAACAAATTTAAGTTTAAGATATGGGGACAAGAAACTTTTTGAAGATGTAAACCTTAAATTTACACCTGG
TAACTGCTATGGTGTTATAGGTGCTAATGGTGCCGGCAAGAGTACCTTTTTAAAAATTTTATCTGGAGAAATAGAGGCTA
ATACTGGAGATGTATCTATACAGCCGGGAGTTAGAATGTCTATTTTAAAACAAGATCACTTTAAATACGATGAATTTCCT
GTTTTAGAAACAGTTATAATGGGAAATGAAAGACTTTATCAAATAATGAAAGAAAAAGATGCTATATATGCTAAAACTCC
TTTTACAGATGAAGATGGTATAAGAGCCTCTGAACTAGAGGGAGAATTTGCAGAATTAAACGGTTGGGAGGCTGAAGCAG
AAGCTTCATCCTTACTTCAAGGCTTAGGTATAGGCACAGAGCTTCACGAAAAAAATATGAAGGATTTATCCGGTAGTGAA
AAGGTAAAAGTATTACTAGCTCAGGCATTATTCGGTAATCCTGGAGTTCTTATACTAGATGAGCCTACTAACCACTTAGA
TATAAAATCTGTGAACTGGCTTGAAGAATTCTTAATAAATTTTGCAGGAACAGTTATTGTAGTATCCCATGATAGACATT
TCTTAAATAAAGTATGTACTCACATGGCAGATGTTGACTTTGGTAAAATTAAACTATATGTAGGAAACTATGATTTTTGG
TATGAATCTAGCCAATTAGCGCTTCAAATGGCTAAAGATCAAAACAAGAAAAAAGAAGAAAAAATAAAAGAGCTGCAGGA
ATTCATTGCTCGTTTTAGTGCTAATGCATCTAAATCTAAGCAAGCCACTTCCCGTAAAAAATTATTAGATAAAATTGATT
TAGATAACATACAACCTTCTAGTAGAAAATATCCTTACATAGCCTTTAAACCCGAAAGAGAAGTTGGTAATGATATATTA
AGAGTAGAGGGTTTAACTAAAACTATAGACGGAACAAAAGTATTGGATAATATAAGCTTTATAATAGGTAAAGATGATAA
AATAGCTTTTGTAGGAGACGAATTATCTATAACTACTCTATTTAAAATAATATCTGGTGAACTAAAGCCAGATAGTGGTG
AATATAAATGGGGAATAACTATAACAAATGCTTATTTCCCAAAGGATAATTCCGAATACTTTAATGATGTAGATTTAAAT
TTAGTAGATTGGTTAAGACAATACTCCGAAGAAAAATCTGAAAGCTATCTACGTGGATTCCTAGGAAGAATGTTATTCTC
TGGTGAAGAGGCTTTAAAAGAGGTTAAAGTTCTATCTGGTGGAGAAAAAGTTAGATGTATGCTATCAAAAATGATGCTAA
ATAATGCTAATGTAATTATATTAGATCAACCAACTAACCACTTAGACCTAGAATCTATAACTGCACTAAATAATGGTTTA
ATGGACTATAAGAGTAACATATTATTTACTTCTCATGATCATCAATTTATACAAACTATAGCCAATAGAATTATAGAAGT
ATCTCCAACAAAATTTGTTGATAAAAAGGTTACTTATGATGAATATTTAGAAAGCAAATAA

Upstream 100 bases:

>100_bases
TTGAAAAGTTTGAAAGATTAACAAATACCTTCTTTTTAAATGGCTTATTTTATGGTATAATGTCGCGAGAACATAAATTT
TAGTAAAGGATGGTATAGAC

Downstream 100 bases:

>100_bases
AAAACTATTTTGAAAATAAAAATCATAAAATCTAGAATGTATAACTAAATATATGAAAAACACTATCAATTTATTAAAAT
TTGATAGTGTTTATTTTTAA

Product: putative drug resistance ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFP
VLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIRASELEGEFAELNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSE
KVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFAGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPEREVGNDIL
RVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTLFKIISGELKPDSGEYKWGITITNAYFPKDNSEYFNDVDLN
LVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
MDYKSNILFTSHDHQFIQTIANRIIEVSPTKFVDKKVTYDEYLESK

Sequences:

>Translated_526_residues
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFP
VLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIRASELEGEFAELNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSE
KVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFAGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPEREVGNDIL
RVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTLFKIISGELKPDSGEYKWGITITNAYFPKDNSEYFNDVDLN
LVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
MDYKSNILFTSHDHQFIQTIANRIIEVSPTKFVDKKVTYDEYLESK
>Mature_526_residues
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFP
VLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIRASELEGEFAELNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSE
KVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFAGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPEREVGNDIL
RVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTLFKIISGELKPDSGEYKWGITITNAYFPKDNSEYFNDVDLN
LVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
MDYKSNILFTSHDHQFIQTIANRIIEVSPTKFVDKKVTYDEYLESK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27881506, Length=538, Percent_Identity=31.2267657992565, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI148612853, Length=511, Percent_Identity=28.7671232876712, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI10947137, Length=538, Percent_Identity=31.2267657992565, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI10947135, Length=533, Percent_Identity=28.3302063789869, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI69354671, Length=533, Percent_Identity=28.3302063789869, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI105990541, Length=204, Percent_Identity=26.4705882352941, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1787041, Length=528, Percent_Identity=44.6969696969697, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1789751, Length=506, Percent_Identity=31.4229249011858, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI2367384, Length=522, Percent_Identity=30.2681992337165, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1787182, Length=505, Percent_Identity=29.9009900990099, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1787029, Length=246, Percent_Identity=24.390243902439, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786398, Length=238, Percent_Identity=25.2100840336134, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786872, Length=245, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=519, Percent_Identity=31.5992292870906, Blast_Score=224, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17555318, Length=511, Percent_Identity=25.8317025440313, Blast_Score=197, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17559834, Length=511, Percent_Identity=27.3972602739726, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17558664, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=520, Percent_Identity=31.7307692307692, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6321121, Length=530, Percent_Identity=29.2452830188679, Blast_Score=219, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6325030, Length=248, Percent_Identity=30.241935483871, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6324314, Length=373, Percent_Identity=26.5415549597855, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323278, Length=373, Percent_Identity=25.7372654155496, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24666836, Length=512, Percent_Identity=29.8828125, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24642252, Length=537, Percent_Identity=27.3743016759777, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI18859989, Length=537, Percent_Identity=27.3743016759777, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24641342, Length=518, Percent_Identity=29.3436293436293, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI221500365, Length=247, Percent_Identity=25.1012145748988, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007184, Length=247, Percent_Identity=25.1012145748988, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59461; Mature: 59461

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSI
CEEEEEEEEECCCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCEECCCCCEEE
QPGVRMSILKQDHFKYDEFPVLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIRASELE
CCCCEEEHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHCC
GEFAELNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSEKVKVLLAQALFGNPGVLILD
CCHHHCCCCCCHHHHHHHHHHCCCCCHHHHCCHHHCCCCHHHHHHHHHHHCCCCCEEEEC
EPTNHLDIKSVNWLEEFLINFAGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
CCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPS
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SRKYPYIAFKPEREVGNDILRVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTL
CCCCCEEEECCCHHHCCCEEEECCCCCCCCCHHHHCCCEEEEECCCEEEEECCCCHHHHH
FKIISGELKPDSGEYKWGITITNAYFPKDNSEYFNDVDLNLVDWLRQYSEEKSESYLRGF
HHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCC
MDYKSNILFTSHDHQFIQTIANRIIEVSPTKFVDKKVTYDEYLESK
HHHCCCEEEECCCHHHHHHHHHHHEECCCCHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSI
CEEEEEEEEECCCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCEECCCCCEEE
QPGVRMSILKQDHFKYDEFPVLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIRASELE
CCCCEEEHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHCC
GEFAELNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSEKVKVLLAQALFGNPGVLILD
CCHHHCCCCCCHHHHHHHHHHCCCCCHHHHCCHHHCCCCHHHHHHHHHHHCCCCCEEEEC
EPTNHLDIKSVNWLEEFLINFAGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFW
CCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPS
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SRKYPYIAFKPEREVGNDILRVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTL
CCCCCEEEECCCHHHCCCEEEECCCCCCCCCHHHHCCCEEEEECCCEEEEECCCCHHHHH
FKIISGELKPDSGEYKWGITITNAYFPKDNSEYFNDVDLNLVDWLRQYSEEKSESYLRGF
HHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGL
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCC
MDYKSNILFTSHDHQFIQTIANRIIEVSPTKFVDKKVTYDEYLESK
HHHCCCEEEECCCHHHHHHHHHHHEECCCCHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]