Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 226949000

GI number: 226949000

Start: 1964016

End: 1964837

Strand: Direct

Name: appC [H]

Synonym: CLM_1914

Alternate gene names: 226949000

Gene position: 1964016-1964837 (Clockwise)

Preceding gene: 226948999

Following gene: 226949001

Centisome position: 47.27

GC content: 30.05

Gene sequence:

>822_bases
ATGAAAAAGTATTGTAAAATTTTTAAAAAATGTTCTATTATAGGTAAATTATCTTTATTAGTAGCATTTGTTTTTATAAT
TGTAGCTATTTTATGTCCACTATTATGTAAACATCCTTATAATGTACCCAGTGGAGGTGCTTTAAATTCTCCATCTATGG
AACATATTCTAGGTACAGACGATTTAGGAATAGACCTATGGTCTCAGATTTGTTATGGTGGAAGGATAAGTATAACTTTA
GGTGTATCTATAGCTCTTTTAGCTGGTACTTTTGGTAGTTTTGTAGGAATAATTTCAGGTTATTATGGAGGTATAATTGA
CAAATTTCTAATGAGATTTACAGACTTGGTGCTAGTATTACCGCAGCTTCCTATTATGATAGTTCTTGCTGCTTTTTTGG
GGCCTAAATTAAAAAATGTAATAATAGTACTAAGCATATTTTCTTGGATAGAGCCTTCTAGAGTAATAAGATCCAAAGTT
ATGTCTATAAAAGATGAAAATTATATAAAAGCGGCTAAAAGTTATGGAGCAAGCTTTTTTCATATATTCAGCAAGCATAT
ATTGCCTCAAATTTTCCCACTAGTAAGCATTAGTATGGTAAAAATCATAAGTAAAGCAATAATAGCAGAATCCTCCCTAT
CTTTTTTAGGATTAGGAGATCCAGTATCTAAAAGCTGGGGAATGATCTTAAATCATGCTATAGATTTTGATGGGATATAC
TTTACAGATTATTGGAAATGGTGGATTACAGCACCTTTACTTTCTATTATTATTTTAGTATTATCCTTTGCTTTTATAGG
GAAAGAGATAGAAAGTTTTTAA

Upstream 100 bases:

>100_bases
TATACAGGGTATATTTTTAATAGTTACTTTTATGGTTATTTTTATGAATTTAATTTCAGATATGTTTTATAAAAAATTAG
ATCCAAGGGTGAGATAATAT

Downstream 100 bases:

>100_bases
TATATTACATATCAATTGGAGGGAATTTTATTGAAAGACTTGCTAATAGTAAGAGACTTATCTGTTTATTACGAAAATGA
AAAGTTATATAAAGCAGTAG

Product: peptide/opine/nickel uptake ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MKKYCKIFKKCSIIGKLSLLVAFVFIIVAILCPLLCKHPYNVPSGGALNSPSMEHILGTDDLGIDLWSQICYGGRISITL
GVSIALLAGTFGSFVGIISGYYGGIIDKFLMRFTDLVLVLPQLPIMIVLAAFLGPKLKNVIIVLSIFSWIEPSRVIRSKV
MSIKDENYIKAAKSYGASFFHIFSKHILPQIFPLVSISMVKIISKAIIAESSLSFLGLGDPVSKSWGMILNHAIDFDGIY
FTDYWKWWITAPLLSIIILVLSFAFIGKEIESF

Sequences:

>Translated_273_residues
MKKYCKIFKKCSIIGKLSLLVAFVFIIVAILCPLLCKHPYNVPSGGALNSPSMEHILGTDDLGIDLWSQICYGGRISITL
GVSIALLAGTFGSFVGIISGYYGGIIDKFLMRFTDLVLVLPQLPIMIVLAAFLGPKLKNVIIVLSIFSWIEPSRVIRSKV
MSIKDENYIKAAKSYGASFFHIFSKHILPQIFPLVSISMVKIISKAIIAESSLSFLGLGDPVSKSWGMILNHAIDFDGIY
FTDYWKWWITAPLLSIIILVLSFAFIGKEIESF
>Mature_273_residues
MKKYCKIFKKCSIIGKLSLLVAFVFIIVAILCPLLCKHPYNVPSGGALNSPSMEHILGTDDLGIDLWSQICYGGRISITL
GVSIALLAGTFGSFVGIISGYYGGIIDKFLMRFTDLVLVLPQLPIMIVLAAFLGPKLKNVIIVLSIFSWIEPSRVIRSKV
MSIKDENYIKAAKSYGASFFHIFSKHILPQIFPLVSISMVKIISKAIIAESSLSFLGLGDPVSKSWGMILNHAIDFDGIY
FTDYWKWWITAPLLSIIILVLSFAFIGKEIESF

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=237, Percent_Identity=32.0675105485232, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787760, Length=266, Percent_Identity=30.8270676691729, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787498, Length=260, Percent_Identity=32.3076923076923, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789964, Length=222, Percent_Identity=31.981981981982, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788505, Length=224, Percent_Identity=30.3571428571429, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789889, Length=233, Percent_Identity=28.755364806867, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787549, Length=220, Percent_Identity=29.0909090909091, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30210; Mature: 30210

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00443 GATASE_TYPE_II ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]